Inactivation of the lysine binding sites of human plasminogen (hPg) reveals novel structural requirements for the tight hPg conformation, M-protein binding, and rapid activation

por Ayinuola, Yetunde A., Castellino, Francis J.
Publicado 2023

Binding of the kringle‐2 domain of human plasminogen to streptococcal PAM‐type M‐protein causes dissociation of PAM dimers

por Ayinuola, Olawole, Ayinuola, Yetunde A., Qiu, Cunjia, Lee, Shaun W., Ploplis, Victoria A., Castellino, Francis J.
Publicado 2021

Evolution of Streptococcus pyogenes has maximized the efficiency of the Sortase A cleavage motif for cell wall transpeptidation

por Readnour, Bradley M., Ayinuola, Yetunde A., Russo, Brady T., Liang, Zhong, Lee, Shaun W., Ploplis, Victoria A., Fischetti, Vincent A., Castellino, Francis J.
Publicado 2022

Streptococcus co-opts a conformational lock in human plasminogen to facilitate streptokinase cleavage and bacterial virulence

por Ayinuola, Yetunde A., Brito-Robinson, Teresa, Ayinuola, Olawole, Beck, Julia E., Cruz-Topete, Diana, Lee, Shaun W., Ploplis, Victoria A., Castellino, Francis J.
Publicado 2020

Relationships Between Plasminogen-Binding M-Protein and Surface Enolase for Human Plasminogen Acquisition and Activation in Streptococcus pyogenes

por Ayinuola, Yetunde A., Tjia-Fleck, Sheiny, Readnour, Bradley M., Liang, Zhong, Ayinuola, Olawole, Paul, Lake N., Lee, Shaun W., Fischetti, Vincent A., Ploplis, Victoria A., Castellino, Francis J.
Publicado 2022

Group A Streptococcus-Induced Activation of Human Plasminogen Is Required for Keratinocyte Wound Retraction and Rapid Clot Dissolution

por Vu, Henry M., Hammers, Daniel E., Liang, Zhong, Nguyen, Gabrielle L., Benz, Mary E., Moran, Thomas E., Higashi, Dustin L., Park, Claudia J., Ayinuola, Yetunde A., Donahue, Deborah L., Flores-Mireles, Ana L., Ploplis, Victoria A., Castellino, Francis J., Lee, Shaun W.
Publicado 2021