Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin

por Lee, Young-Tae, Ayoub, Alex, Park, Sang-Ho, Sha, Liang, Xu, Jing, Mao, Fengbiao, Zheng, Wei, Zhang, Yang, Cho, Uhn-Soo, Dou, Yali
Publicado 2021

Cryo-EM structure of the human MLL1 core complex bound to the nucleosome

por Park, Sang Ho, Ayoub, Alex, Lee, Young-Tae, Xu, Jing, Kim, Hanseong, Zheng, Wei, Zhang, Biao, Sha, Liang, An, Sojin, Zhang, Yang, Cianfrocco, Michael A., Su, Min, Dou, Yali, Cho, Uhn-Soo
Publicado 2019

Publisher Correction: Cryo-EM structure of the human MLL1 core complex bound to the nucleosome

por Park, Sang Ho, Ayoub, Alex, Lee, Young-Tae, Xu, Jing, Kim, Hanseong, Zheng, Wei, Zhang, Biao, Sha, Liang, An, Sojin, Zhang, Yang, Cianfrocco, Michael A., Su, Min, Dou, Yali, Cho, Uhn-Soo
Publicado 2020

Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2′-Deoxyzebularine Analogues

por Kvach, Maksim V., Barzak, Fareeda M., Harjes, Stefan, Schares, Henry A. M., Jameson, Geoffrey B., Ayoub, Alex M., Moorthy, Ramkumar, Aihara, Hideki, Harris, Reuben S., Filichev, Vyacheslav V., Harki, Daniel A., Harjes, Elena
Publicado 2018

Illuminating protein space with a programmable generative model

por Ingraham, John B., Baranov, Max, Costello, Zak, Barber, Karl W., Wang, Wujie, Ismail, Ahmed, Frappier, Vincent, Lord, Dana M., Ng-Thow-Hing, Christopher, Van Vlack, Erik R., Tie, Shan, Xue, Vincent, Cowles, Sarah C., Leung, Alan, Rodrigues, João V., Morales-Perez, Claudio L., Ayoub, Alex M., Green, Robin, Puentes, Katherine, Oplinger, Frank, Panwar, Nishant V., Obermeyer, Fritz, Root, Adam R., Beam, Andrew L., Poelwijk, Frank J., Grigoryan, Gevorg
Publicado 2023