Species-specific differences in NPC1 protein trafficking govern therapeutic response in Niemann-Pick type C disease

por Schultz, Mark L., Schache, Kylie J., Azaria, Ruth D., Kuiper, Esmée Q., Erwood, Steven, Ivakine, Evgueni A., Farhat, Nicole Y., Porter, Forbes D., Pathmasiri, Koralege C., Cologna, Stephanie M., Uhler, Michael D., Lieberman, Andrew P.
Publicado 2022

Enrichment of NPC1-deficient cells with the lipid LBPA stimulates autophagy, improves lysosomal function, and reduces cholesterol storage

por Ilnytska, Olga, Lai, Kimberly, Gorshkov, Kirill, Schultz, Mark L., Tran, Bruce Nguyen, Jeziorek, Maciej, Kunkel, Thaddeus J., Azaria, Ruth D., McLoughlin, Hayley S., Waghalter, Miriam, Xu, Yang, Schlame, Michael, Altan-Bonnet, Nihal, Zheng, Wei, Lieberman, Andrew P., Dobrowolski, Radek, Storch, Judith
Publicado 2021

Adipocyte-Specific Deletion of Lamin A/C Largely Models Human Familial Partial Lipodystrophy Type 2

por Corsa, Callie A.S., Walsh, Carolyn M., Bagchi, Devika P., Foss Freitas, Maria C., Li, Ziru, Hardij, Julie, Granger, Katrina, Mori, Hiroyuki, Schill, Rebecca L., Lewis, Kenneth T., Maung, Jessica N., Azaria, Ruth D., Rothberg, Amy E., Oral, Elif A., MacDougald, Ormond A.
Publicado 2021

Estrogen receptor inhibition mediates radiosensitization of ER-positive breast cancer models

por Michmerhuizen, Anna R., Lerner, Lynn M., Pesch, Andrea M., Ward, Connor, Schwartz, Rachel, Wilder-Romans, Kari, Liu, Meilan, Nino, Charles, Jungles, Kassidy, Azaria, Ruth, Jelley, Alexa, Zambrana Garcia, Nicole, Harold, Alexis, Zhang, Amanda, Wharram, Bryan, Hayes, Daniel F., Rae, James M., Pierce, Lori J., Speers, Corey W.
Publicado 2022

Publisher Correction: Estrogen receptor inhibition mediates radiosensitization of ER-positive breast cancer models

por Michmerhuizen, Anna R., Lerner, Lynn M., Pesch, Andrea M., Ward, Connor, Schwartz, Rachel, Wilder-Romans, Kari, Liu, Meilan, Nino, Charles, Jungles, Kassidy, Azaria, Ruth, Jelley, Alexa, Zambrana Garcia, Nicole, Harold, Alexis, Zhang, Amanda, Wharram, Bryan, Hayes, Daniel F., Rae, James M., Pierce, Lori J., Speers, Corey W.
Publicado 2022

Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann–Pick diseases

por Schultz, Mark L., Fawaz, Maria V., Azaria, Ruth D., Hollon, Todd C., Liu, Elaine A., Kunkel, Thaddeus J., Halseth, Troy A., Krus, Kelsey L., Ming, Ran, Morin, Emily E., McLoughlin, Hayley S., Bushart, David D., Paulson, Henry L., Shakkottai, Vikram G., Orringer, Daniel A., Schwendeman, Anna S., Lieberman, Andrew P.
Publicado 2019