Development of Chemical Proteomics for the Folateome and Analysis of the Kinetoplastid Folateome

por Webster, Lauren A., Thomas, Michael, Urbaniak, Michael, Wyllie, Susan, Ong, Han, Tinti, Michele, Fairlamb, Alan H., Boesche, Markus, Ghidelli-Disse, Sonja, Drewes, Gerard, Gilbert, Ian H.
Publicado 2018

Loss of N-Glycanase 1 Alters Transcriptional and Translational Regulation in K562 Cell Lines

por Mueller, William F., Jakob, Petra, Sun, Han, Clauder-Münster, Sandra, Ghidelli-Disse, Sonja, Ordonez, Diana, Boesche, Markus, Bantscheff, Marcus, Collier, Paul, Haase, Bettina, Benes, Vladimir, Paulsen, Malte, Sehr, Peter, Lewis, Joe, Drewes, Gerard, Steinmetz, Lars M.
Publicado 2020

Development of Chemical Entities Endowed with Potent Fast-Killing Properties against Plasmodium falciparum Malaria Parasites

por Matralis, Alexios N., Malik, Adnan, Penzo, Maria, Moreno, Inmaculada, Almela, Maria J., Camino, Isabel, Crespo, Benigno, Saadeddin, Anas, Ghidelli-Disse, Sonja, Rueda, Lourdes, Calderon, Felix, Osborne, Simon A., Drewes, Gerard, Böesche, Markus, Fernández-Álvaro, Elena, Martin Hernando, Jose Ignacio, Baker, David A.
Publicado 2019

Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds

por Crowther, Gregory J., Hillesland, Heidi K., Keyloun, Katelyn R., Reid, Molly C., Lafuente-Monasterio, Maria Jose, Ghidelli-Disse, Sonja, Leonard, Stephen E., He, Panqing, Jones, Jackson C., Krahn, Mallory M., Mo, Jack S., Dasari, Kartheek S., Fox, Anna M. W., Boesche, Markus, El Bakkouri, Majida, Rivas, Kasey L., Leroy, Didier, Hui, Raymond, Drewes, Gerard, Maly, Dustin J., Van Voorhis, Wesley C., Ojo, Kayode K.
Publicado 2016

Cyclin-dependent kinase 12, a novel drug target for visceral leishmaniasis

por Wyllie, Susan, Thomas, Michael, Patterson, Stephen, Crouch, Sabrinia, De Rycker, Manu, Lowe, Rhiannon, Gresham, Stephanie, Urbaniak, Michael D., Otto, Thomas D., Stojanovski, Laste, Simeons, Frederick, Manthri, Sujatha, MacLean, Lorna M., Zuccotto, Fabio, Homeyer, Nadine, Pflaumer, Hannah, Boesche, Markus, Sastry, Lalitha, Connolly, Paul, Albrecht, Sebastian, Berriman, Matt, Drewes, Gerard, Gray, David W., Ghidelli-Disse, Sonja, Dixon, Susan, Fiandor, Jose M., Wyatt, Paul G., Ferguson, Michael A. J., Fairlamb, Alan H., Miles, Timothy J., Read, Kevin D., Gilbert, Ian H.
Publicado 2018

Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure–Activity Relationship and Target I...

por Wilson, Colin R., Gessner, Richard K., Moosa, Atica, Seldon, Ronnett, Warner, Digby F., Mizrahi, Valerie, Soares de Melo, Candice, Simelane, Sandile B., Nchinda, Aloysius, Abay, Efrem, Taylor, Dale, Njoroge, Mathew, Brunschwig, Christel, Lawrence, Nina, Boshoff, Helena I. M., Barry, Clifton E., Sirgel, Frederick A., van Helden, Paul, Harris, C. John, Gordon, Richard, Ghidelli-Disse, Sonja, Pflaumer, Hannah, Boesche, Markus, Drewes, Gerard, Sanz, Olalla, Santos, Gracia, Rebollo-Lopez, Maria José, Urones, Beatriz, Selenski, Carolyn, Lafuente-Monasterio, Maria Jose, Axtman, Matthew, Lelièvre, Joël, Ballell, Lluis, Mueller, Rudolf, Street, Leslie J., Ghorpade, Sandeep R., Chibale, Kelly
Publicado 2017

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

por Thomas, Michael G., De Rycker, Manu, Ajakane, Myriam, Albrecht, Sébastian, Álvarez-Pedraglio, Ana Isabel, Boesche, Markus, Brand, Stephen, Campbell, Lorna, Cantizani-Perez, Juan, Cleghorn, Laura A.T., Copley, Royston C.B., Crouch, Sabrinia D., Daugan, Alain, Drewes, Gerard, Ferrer, Santiago, Ghidelli-Disse, Sonja, Gonzalez, Silvia, Gresham, Stephanie L., Hill, Alan P., Hindley, Sean J., Lowe, Rhiannon M., MacKenzie, Claire J., MacLean, Lorna, Manthri, Sujatha, Martin, Franck, Miguel-Siles, Juan, Nguyen, Van Loc, Norval, Suzanne, Osuna-Cabello, Maria, Woodland, Andrew, Patterson, Stephen, Pena, Imanol, Quesada-Campos, Maria Teresa, Reid, Iain H., Revill, Charlotte, Riley, Jennifer, Ruiz-Gomez, Jose Ramon, Shishikura, Yoko, Simeons, Frederick R.C., Smith, Alasdair, Smith, Victoria C., Spinks, Daniel, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Underwood, Tim, Gray, David W., Fiandor, Jose M., Gilbert, Ian H., Wyatt, Paul G., Read, Kevin D., Miles, Timothy J.
Publicado 2018