Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles and Their Potential as Novel Immunomodulatory Therapeutic Agents

por Börger, Verena, Bremer, Michel, Ferrer-Tur, Rita, Gockeln, Lena, Stambouli, Oumaima, Becic, Amina, Giebel, Bernd
Publicado 2017

Immunomodulatory potential of mesenchymal stromal cell-derived extracellular vesicles in chondrocyte inflammation

por Ossendorff, Robert, Grad, Sibylle, Tertel, Tobias, Wirtz, Dieter C., Giebel, Bernd, Börger, Verena, Schildberg, Frank A.
Publicado 2023

Mesenchymal Stromal Cell-Derived Extracellular Vesicles Reduce Neuroinflammation, Promote Neural Cell Proliferation and Improve Oligodendrocyte Maturation in Neonatal Hypoxic-Ische...

por Kaminski, Nicole, Köster, Christian, Mouloud, Yanis, Börger, Verena, Felderhoff-Müser, Ursula, Bendix, Ivo, Giebel, Bernd, Herz, Josephine
Publicado 2020

Individual Immune-Modulatory Capabilities of MSC-Derived Extracellular Vesicle (EV) Preparations and Recipient-Dependent Responsiveness

por Kordelas, Lambros, Schwich, Esther, Dittrich, Robin, Horn, Peter A., Beelen, Dietrich W., Börger, Verena, Giebel, Bernd, Rebmann, Vera
Publicado 2019

Mesenchymal stromal cell-derived small extracellular vesicles promote neurological recovery and brain remodeling after distal middle cerebral artery occlusion in aged rats

por Dumbrava, Danut-Adrian, Surugiu, Roxana, Börger, Verena, Ruscu, Mihai, Tertel, Tobias, Giebel, Bernd, Hermann, Dirk M., Popa-Wagner, Aurel
Publicado 2021

The Employment of the Surface Plasmon Resonance (SPR) Microscopy Sensor for the Detection of Individual Extracellular Vesicles and Non-Biological Nanoparticles

por Sharar, Nour, Wüstefeld, Konstantin, Talukder, Rahat Morad, Skolnik, Julija, Kaufmann, Katharina, Giebel, Bernd, Börger, Verena, Nolte, Friedrich, Watzl, Carsten, Weichert, Frank, Hergenröder, Roland, Shpacovitch, Victoria
Publicado 2023

Single Extracellular Vesicle Analysis Performed by Imaging Flow Cytometry and Nanoparticle Tracking Analysis Evaluate the Accuracy of Urinary Extracellular Vesicle Preparation Tech...

por Droste, Marvin, Tertel, Tobias, Jeruschke, Stefanie, Dittrich, Robin, Kontopoulou, Evangelia, Walkenfort, Bernd, Börger, Verena, Hoyer, Peter F., Büscher, Anja K., Thakur, Basant K., Giebel, Bernd
Publicado 2021

Anti-Inflammatory Mesenchymal Stromal Cell-Derived Extracellular Vesicles Improve Pathology in Niemann–Pick Type C Disease

por Van Hoecke, Lien, Van Cauwenberghe, Caroline, Börger, Verena, Bruggeman, Arnout, Castelein, Jonas, Van Imschoot, Griet, Van Wonterghem, Elien, Dittrich, Robin, Claeys, Wouter, Xie, Junhua, Giebel, Bernd, Vandenbroucke, Roosmarijn E.
Publicado 2021

Postischemic Neuroprotection Associated With Anti-Inflammatory Effects by Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles in Aged Mice

por Wang, Chen, Börger, Verena, Mohamud Yusuf, Ayan, Tertel, Tobias, Stambouli, Oumaima, Murke, Florian, Freund, Nico, Kleinschnitz, Christoph, Herz, Josephine, Gunzer, Matthias, Popa-Wagner, Aurel, Doeppner, Thorsten R., Giebel, Bernd, Hermann, Dirk M.
Publicado 2021

Acid sphingomyelinase deactivation post-ischemia promotes brain angiogenesis and remodeling by small extracellular vesicles

por Mohamud Yusuf, Ayan, Hagemann, Nina, Zhang, Xiaoni, Zafar, Maria, Hussner, Tanja, Bromkamp, Carolin, Martiny, Carlotta, Tertel, Tobias, Börger, Verena, Schumacher, Fabian, Solari, Fiorella A., Hasenberg, Mike, Kleinschnitz, Christoph, Doeppner, Thorsten R., Kleuser, Burkhard, Sickmann, Albert, Gunzer, Matthias, Giebel, Bernd, Kolesnick, Richard, Gulbins, Erich, Hermann, Dirk M.
Publicado 2022

Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recov...

por Gregorius, Jonas, Wang, Chen, Stambouli, Oumaima, Hussner, Tanja, Qi, Yachao, Tertel, Tobias, Börger, Verena, Mohamud Yusuf, Ayan, Hagemann, Nina, Yin, Dongpei, Dittrich, Robin, Mouloud, Yanis, Mairinger, Fabian D., Magraoui, Fouzi El, Popa-Wagner, Aurel, Kleinschnitz, Christoph, Doeppner, Thorsten R., Gunzer, Matthias, Meyer, Helmut E., Giebel, Bernd, Hermann, Dirk M.
Publicado 2021

Precipitation with polyethylene glycol followed by washing and pelleting by ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small and large...

por Ludwig, Anna-Kristin, De Miroschedji, Kyra, Doeppner, Thorsten R., Börger, Verena, Ruesing, Johannes, Rebmann, Vera, Durst, Stephan, Jansen, Sören, Bremer, Michel, Behrmann, Elmar, Singer, Bernhard B., Jastrow, Holger, Kuhlmann, Jan Dominik, El Magraoui, Fouzi, Meyer, Helmut E., Hermann, Dirk M., Opalka, Bertram, Raunser, Stefan, Epple, Matthias, Horn, Peter A., Giebel, Bernd
Publicado 2018

International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other ce...

por Börger, Verena, Weiss, Daniel J., Anderson, Johnathon D., Borràs, Francesc E., Bussolati, Benedetta, Carter, David R.F., Dominici, Massimo, Falcón-Pérez, Juan M., Gimona, Mario, Hill, Andrew F., Hoffman, Andrew M., de Kleijn, Dominique, Levine, Bruce L., Lim, Rebecca, Lötvall, Jan, Mitsialis, S. Alex, Monguió-Tortajada, Marta, Muraca, Maurizio, Nieuwland, Rienk, Nowocin, Anna, O'Driscoll, Lorraine, Ortiz, Luis A., Phinney, Donald G, Reischl, Ilona, Rohde, Eva, Sanzenbacher, Ralf, Théry, Clotilde, Toh, Wei Seong, Witwer, Kenneth W., Lim, Sai Kiang, Giebel, Bernd
Publicado 2020

Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper

por Lener, Thomas, Gimona, Mario, Aigner, Ludwig, Börger, Verena, Buzas, Edit, Camussi, Giovanni, Chaput, Nathalie, Chatterjee, Devasis, Court, Felipe A., del Portillo, Hernando A., O'Driscoll, Lorraine, Fais, Stefano, Falcon-Perez, Juan M., Felderhoff-Mueser, Ursula, Fraile, Lorenzo, Gho, Yong Song, Görgens, André, Gupta, Ramesh C., Hendrix, An, Hermann, Dirk M., Hill, Andrew F., Hochberg, Fred, Horn, Peter A., de Kleijn, Dominique, Kordelas, Lambros, Kramer, Boris W., Krämer-Albers, Eva-Maria, Laner-Plamberger, Sandra, Laitinen, Saara, Leonardi, Tommaso, Lorenowicz, Magdalena J., Lim, Sai Kiang, Lötvall, Jan, Maguire, Casey A., Marcilla, Antonio, Nazarenko, Irina, Ochiya, Takahiro, Patel, Tushar, Pedersen, Shona, Pocsfalvi, Gabriella, Pluchino, Stefano, Quesenberry, Peter, Reischl, Ilona G., Rivera, Francisco J., Sanzenbacher, Ralf, Schallmoser, Katharina, Slaper-Cortenbach, Ineke, Strunk, Dirk, Tonn, Torsten, Vader, Pieter, van Balkom, Bas W. M., Wauben, Marca, Andaloussi, Samir El, Théry, Clotilde, Rohde, Eva, Giebel, Bernd
Publicado 2015