New insights into the phosphorylation of the threonine motif of the β1 integrin cytoplasmic domain

por Böttcher, Ralph T, Strohmeyer, Nico, Aretz, Jonas, Fässler, Reinhard
Publicado 2022

Quantitative single-protein imaging reveals molecular complex formation of integrin, talin, and kindlin during cell adhesion

por Fischer, Lisa S., Klingner, Christoph, Schlichthaerle, Thomas, Strauss, Maximilian T., Böttcher, Ralph, Fässler, Reinhard, Jungmann, Ralf, Grashoff, Carsten
Publicado 2021

Molecular-scale visualization of sarcomere contraction within native cardiomyocytes

por Burbaum, Laura, Schneider, Jonathan, Scholze, Sarah, Böttcher, Ralph T., Baumeister, Wolfgang, Schwille, Petra, Plitzko, Jürgen M., Jasnin, Marion
Publicado 2021

Unc5B Interacts with FLRT3 and Rnd1 to Modulate Cell Adhesion in Xenopus Embryos

por Karaulanov, Emil, Böttcher, Ralph T., Stannek, Peter, Wu, Wei, Rau, Marlene, Ogata, Souichi, Cho, Ken W. Y., Niehrs, Christof
Publicado 2009

Preserved Morphology and Physiology of Excitatory Synapses in Profilin1-Deficient Mice

por Görlich, Andreas, Zimmermann, Anika-Maria, Schober, Doreen, Böttcher, Ralph T., Sassoè-Pognetto, Marco, Friauf, Eckhard, Witke, Walter, Rust, Marco B.
Publicado 2012

Molecular determinants of αVβ5 localization in flat clathrin lattices – role of αVβ5 in cell adhesion and proliferation

por Zuidema, Alba, Wang, Wei, Kreft, Maaike, Bleijerveld, Onno B., Hoekman, Liesbeth, Aretz, Jonas, Böttcher, Ralph T., Fässler, Reinhard, Sonnenberg, Arnoud
Publicado 2022

Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading

por Böttcher, Ralph T., Veelders, Maik, Rombaut, Pascaline, Faix, Jan, Theodosiou, Marina, Stradal, Theresa E., Rottner, Klemens, Zent, Roy, Herzog, Franz, Fässler, Reinhard
Publicado 2017

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

por Theodosiou, Marina, Widmaier, Moritz, Böttcher, Ralph T, Rognoni, Emanuel, Veelders, Maik, Bharadwaj, Mitasha, Lambacher, Armin, Austen, Katharina, Müller, Daniel J, Zent, Roy, Fässler, Reinhard
Publicado 2016

More Is Not Always Better—the Double-Headed Role of Fibronectin in Staphylococcus aureus Host Cell Invasion

por Niemann, Silke, Nguyen, Minh-Thu, Eble, Johannes A., Chasan, Achmet I., Mrakovcic, Maria, Böttcher, Ralph T., Preissner, Klaus T., Roßlenbroich, Steffen, Peters, Georg, Herrmann, Mathias
Publicado 2021

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous epithelial stem cell proliferation

por Rognoni, Emanuel, Widmaier, Moritz, Jakobson, Madis, Ruppert, Raphael, Ussar, Siegfried, Katsougkri, Despoina, Böttcher, Ralph T., Lai-Cheong, Joey E., Rifkin, Daniel B., McGrath, John A., Fässler, Reinhard
Publicado 2014

FAK auto-phosphorylation site tyrosine 397 is required for development but dispensable for normal skin homeostasis

por Heim, Joel B., McDonald, Cera A., Wyles, Saranya P., Sominidi-Damodaran, Sindhuja, Squirewell, Edwin J., Li, Ming, Motsonelidze, Catherine, Böttcher, Ralph T., van Deursen, Jan, Meves, Alexander
Publicado 2018

Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions

por Orré, Thomas, Joly, Adrien, Karatas, Zeynep, Kastberger, Birgit, Cabriel, Clément, Böttcher, Ralph T., Lévêque-Fort, Sandrine, Sibarita, Jean-Baptiste, Fässler, Reinhard, Wehrle-Haller, Bernhard, Rossier, Olivier, Giannone, Grégory
Publicado 2021

PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis

por Mana, Giulia, Clapero, Fabiana, Panieri, Emiliano, Panero, Valentina, Böttcher, Ralph T., Tseng, Hui-Yuan, Saltarin, Federico, Astanina, Elena, Wolanska, Katarzyna I., Morgan, Mark R., Humphries, Martin J., Santoro, Massimo M., Serini, Guido, Valdembri, Donatella
Publicado 2016

Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt

por Yazlovitskaya, Eugenia M., Tseng, Hui-Yuan, Viquez, Olga, Tu, Tianxiang, Mernaugh, Glenda, McKee, Karen K., Riggins, Karen, Quaranta, Vito, Pathak, Amrita, Carter, Bruce D., Yurchenco, Peter, Sonnenberg, Arnoud, Böttcher, Ralph T., Pozzi, Ambra, Zent, Roy
Publicado 2015

The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 Activation

por Borza, Corina M., Bolas, Gema, Zhang, Xiuqi, Browning Monroe, Mary Beth, Zhang, Ming-Zhi, Meiler, Jens, Skwark, Marcin J., Harris, Raymond C., Lapierre, Lynne A., Goldenring, James R., Hook, Magnus, Rivera, Jose, Brown, Kyle L., Leitinger, Birgit, Tyska, Matthew J., Moser, Markus, Böttcher, Ralph T., Zent, Roy, Pozzi, Ambra
Publicado 2022