Network neighbors of viral targets and differentially expressed genes in COVID-19 are drug target candidates

por Zambrana, Carme, Xenos, Alexandros, Böttcher, René, Malod-Dognin, Noël, Pržulj, Nataša
Publicado 2021

Gene-expression analysis of gleason grade 3 tumor glands embedded in low- and high-risk prostate cancer

por Hoogland, A. Marije, Böttcher, René, Verhoef, Esther, Jenster, Guido, van Leenders, Geert J.L.H.
Publicado 2016

A mononucleotide repeat in PRRT2 is an important, frequent target of mismatch repair deficiency in cancer

por Alves, Inês Teles, Cano, David, Böttcher, René, van der Korput, Hetty, Dinjens, Winand, Jenster, Guido, Trapman, Jan
Publicado 2016

Regulation of transcription elongation in response to osmostress

por Silva, Andrea, Cavero, Santiago, Begley, Victoria, Solé, Carme, Böttcher, René, Chávez, Sebastián, Posas, Francesc, de Nadal, Eulàlia
Publicado 2017

CHIKV infection reprograms codon optimality to favor viral RNA translation by altering the tRNA epitranscriptome

por Jungfleisch, Jennifer, Böttcher, René, Talló-Parra, Marc, Pérez-Vilaró, Gemma, Merits, Andres, Novoa, Eva Maria, Díez, Juana
Publicado 2022

Using a priori knowledge to align sequencing reads to their exact genomic position

por Böttcher, René, Amberg, Ronny, Ruzius, F. P., Guryev, V., Verhaegh, Wim F. J., Beyerlein, Peter, van der Zaag, P. J.
Publicado 2012

Rapid reversible changes in compartments and local chromatin organization revealed by hyperosmotic shock

por Amat, Ramon, Böttcher, René, Le Dily, François, Vidal, Enrique, Quilez, Javier, Cuartero, Yasmina, Beato, Miguel, de Nadal, Eulàlia, Posas, Francesc
Publicado 2019

Data-driven identification of inherent features of eukaryotic stress-responsive genes

por Latorre, Pablo, Böttcher, René, Nadal-Ribelles, Mariona, Li, Constance H, Solé, Carme, Martínez-Cebrián, Gerard, Boutros, Paul C, Posas, Francesc, de Nadal, Eulàlia
Publicado 2022

Functional Network Analysis Reveals the Relevance of SKIIP in the Regulation of Alternative Splicing by p38 SAPK

por Carbonell, Caterina, Ulsamer, Arnau, Vivori, Claudia, Papasaikas, Panagiotis, Böttcher, René, Joaquin, Manel, Miñana, Belén, Tejedor, Juan Ramón, de Nadal, Eulàlia, Valcárcel, Juan, Posas, Francesc
Publicado 2019

Host-derived circular RNAs display proviral activities in Hepatitis C virus-infected cells

por Chen, Tzu-Chun, Tallo-Parra, Marc, Cao, Qian M., Kadener, Sebastian, Böttcher, René, Pérez-Vilaró, Gemma, Boonchuen, Pakpoom, Somboonwiwat, Kunlaya, Díez, Juana, Sarnow, Peter
Publicado 2020

Novel long non-coding RNAs are specific diagnostic and prognostic markers for prostate cancer

por Böttcher, René, Hoogland, A. Marije, Dits, Natasja, Verhoef, Esther I., Kweldam, Charlotte, Waranecki, Piotr, Bangma, Chris H., van Leenders, Geert J.L.H., Jenster, Guido
Publicado 2015

A genetic analysis reveals novel histone residues required for transcriptional reprogramming upon stress

por Viéitez, Cristina, Martínez-Cebrián, Gerard, Solé, Carme, Böttcher, René, Potel, Clement M, Savitski, Mikhail M, Onnebo, Sara, Fabregat, Marc, Shilatifard, Ali, Posas, Francesc, de Nadal, Eulàlia
Publicado 2020

Human PDE4D isoform composition is deregulated in primary prostate cancer and indicative for disease progression and development of distant metastases

por Böttcher, René, Dulla, Kalyan, van Strijp, Dianne, Dits, Natasja, Verhoef, Esther I., Baillie, George S., van Leenders, Geert J.L.H., Houslay, Miles D., Jenster, Guido, Hoffmann, Ralf
Publicado 2016

LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions

por Serra, Selma A., Stojakovic, Predrag, Amat, Ramon, Rubio-Moscardo, Fanny, Latorre, Pablo, Seisenbacher, Gerhard, Canadell, David, Böttcher, René, Aregger, Michael, Moffat, Jason, de Nadal, Eulàlia, Valverde, Miguel A., Posas, Francesc
Publicado 2021

Loss of SLCO1B3 drives taxane resistance in prostate cancer

por de Morrée, Ellen S, Böttcher, René, van Soest, Robert J, Aghai, Ashraf, de Ridder, Corrina M, Gibson, Alice A, Mathijssen, Ron HJ, Burger, Herman, Wiemer, Erik AC, Sparreboom, Alex, de Wit, Ronald, van Weerden, Wytske M
Publicado 2016

The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins

por Blasco-Moreno, Bernat, de Campos-Mata, Leire, Böttcher, René, García-Martínez, José, Jungfleisch, Jennifer, Nedialkova, Danny D., Chattopadhyay, Shiladitya, Gas, María-Eugenia, Oliva, Baldomero, Pérez-Ortín, José E., Leidel, Sebastian A., Choder, Mordechai, Díez, Juana
Publicado 2019

Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations

por Böttcher, René, Kweldam, Charlotte F., Livingstone, Julie, Lalonde, Emilie, Yamaguchi, Takafumi N., Huang, Vincent, Yousif, Fouad, Fraser, Michael, Bristow, Robert G., van der Kwast, Theodorus, Boutros, Paul C., Jenster, Guido, van Leenders, Geert J. L. H.
Publicado 2018

Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+ T cells

por Kobayashi-Ishihara, Mie, Frazão Smutná, Katarína, Alonso, Florencia E., Argilaguet, Jordi, Esteve-Codina, Anna, Geiger, Kerstin, Genescà, Meritxell, Grau-Expósito, Judith, Duran-Castells, Clara, Rogenmoser, Selina, Böttcher, René, Jungfleisch, Jennifer, Oliva, Baldomero, Martinez, Javier P., Li, Manqing, David, Michael, Yamagishi, Makoto, Ruiz-Riol, Marta, Brander, Christian, Tsunetsugu-Yokota, Yasuko, Buzon, Maria J., Díez, Juana, Meyerhans, Andreas
Publicado 2023

Fusion transcripts and their genomic breakpoints in polyadenylated and ribosomal RNA–minus RNA sequencing data

por Hoogstrate, Youri, Komor, Malgorzata A, Böttcher, René, van Riet, Job, van de Werken, Harmen J G, van Lieshout, Stef, Hoffmann, Ralf, van den Broek, Evert, Bolijn, Anne S, Dits, Natasja, Sie, Daoud, van der Meer, David, Pepers, Floor, Bangma, Chris H, van Leenders, Geert J L H, Smid, Marcel, French, Pim J, Martens, John W M, van Workum, Wilbert, van der Spek, Peter J, Janssen, Bart, Caldenhoven, Eric, Rausch, Christian, de Jong, Mark, Stubbs, Andrew P, Meijer, Gerrit A, Fijneman, Remond J A, Jenster, Guido W
Publicado 2021