Lipotoxicity as a Barrier for T Cell-Based Therapies

por Böttcher-Loschinski, Romy, Rial Saborido, Judit, Böttcher, Martin, Kahlfuss, Sascha, Mougiakakos, Dimitrios
Publicado 2022

IL‐3 is essential for ICOS‐L stabilization on mast cells, and sustains the IL‐33‐induced RORγt(+) T(reg) generation via enhanced IL‐6 induction

por Drube, Sebastian, Müller, Sylvia, Weber, Franziska, Wegner, Philine, Böttcher‐Loschinski, Romy, Gaestel, Matthias, Hutloff, Andreas, Kamradt, Thomas, Andreas, Nico
Publicado 2021

TIGIT signaling and its influence on T cell metabolism and immune cell function in the tumor microenvironment

por Jantz-Naeem, Nouria, Böttcher-Loschinski, Romy, Borucki, Katrin, Mitchell-Flack, Marisa, Böttcher, Martin, Schraven, Burkhart, Mougiakakos, Dimitrios, Kahlfuss, Sascha
Publicado 2023

Synergistic lethality in chronic myeloid leukemia – targeting oxidative phosphorylation and unfolded protein response effectively complements tyrosine kinase inhibitor treatment

por Häselbarth, Lukas, Gamali, Sara, Saul, Domenica, Krumbholz, Manuela, Böttcher-Loschinski, Romy, Böttcher, Martin, Zou, Deyu, Metzler, Markus, Karow, Axel, Mougiakakos, Dimitrios
Publicado 2023

CLL-Derived Extracellular Vesicles Impair T-Cell Activation and Foster T-Cell Exhaustion via Multiple Immunological Checkpoints

por Böttcher, Martin, Böttcher-Loschinski, Romy, Kahlfuss, Sascha, Aigner, Michael, Gießl, Andreas, Mackensen, Andreas, Schlötzer-Schrehardt, Ursula, Tüting, Thomas, Bruns, Heiko, Mougiakakos, Dimitrios
Publicado 2022

Accumulation of T-cell-suppressive PD-L1(high) extracellular vesicles is associated with GvHD and might impact GvL efficacy

por Baur, Rebecca, Karl, Franziska, Böttcher-Loschinski, Romy, Stoll, Andrej, Völkl, Simon, Gießl, Andreas, Flamann, Cindy, Bruns, Heiko, Schlötzer-Schrehardt, Ursula, Böttcher, Martin, Schewe, Denis M, Fischer, Thomas, Jitschin, Regina, Mackensen, Andreas, Mougiakakos, Dimitrios
Publicado 2023