Gene therapy enters the pharma market: The short story of a long journey

por Büning, Hildegard
Publicado 2013

Adeno-Associated Viral Vectors at the Frontier between Tolerance and Immunity

por Mingozzi, Federico, Büning, Hildegard
Publicado 2015

Capsid Modifications for Targeting and Improving the Efficacy of AAV Vectors

por Büning, Hildegard, Srivastava, Arun
Publicado 2019

Skeletal muscle-directed gene therapy: hijacking the fusogenic properties of muscle cells

por Büning, Hildegard, Morgan, Michael, Schambach, Axel
Publicado 2023

Enhancing the Clinical Potential of AAV Vectors by Capsid Engineering to Evade Pre-Existing Immunity

por Bartel, Melissa, Schaffer, David, Büning, Hildegard
Publicado 2011

Rational Design of Gene Therapy Vectors

por Pan, Dao, Büning, Hildegard, Ling, Chen
Publicado 2019

Light at the end of the tunnel of Corti

por Hanlon, Kilian, Büning, Hildegard, Géléoc, Gwenaëlle S.G.
Publicado 2023

Analyzing the Genotoxicity of Retroviral Vectors in Hematopoietic Cell Gene Therapy

por Biasco, Luca, Rothe, Michael, Büning, Hildegard, Schambach, Axel
Publicado 2017

Use of Cell and Genome Modification Technologies to Generate Improved “Off-the-Shelf” CAR T and CAR NK Cells

por Morgan, Michael A., Büning, Hildegard, Sauer, Martin, Schambach, Axel
Publicado 2020

Towards Clinical Implementation of Adeno-Associated Virus (AAV) Vectors for Cancer Gene Therapy: Current Status and Future Perspectives

por Hacker, Ulrich T., Bentler, Martin, Kaniowska, Dorota, Morgan, Michael, Büning, Hildegard
Publicado 2020

Pyroptotic and Necroptotic Cell Death in the Tumor Microenvironment and Their Potential to Stimulate Anti-Tumor Immune Responses

por Scarpitta, Allan, Hacker, Ulrich T., Büning, Hildegard, Boyer, Olivier, Adriouch, Sahil
Publicado 2021

Gene therapy on the move

por Kaufmann, Kerstin B, Büning, Hildegard, Galy, Anne, Schambach, Axel, Grez, Manuel
Publicado 2013

The Hard Way towards an Antibody-Based HIV-1 Env Vaccine: Lessons from Other Viruses

por Ringel, Oliver, Vieillard, Vincent, Debré, Patrice, Eichler, Jutta, Büning, Hildegard, Dietrich, Ursula
Publicado 2018

Immunogenicity of Novel AAV Capsids for Retinal Gene Therapy

por Gehrke, Miranda, Diedrichs-Möhring, Maria, Bogedein, Jacqueline, Büning, Hildegard, Michalakis, Stylianos, Wildner, Gerhild
Publicado 2022

Characterization of a Novel Third-Generation Anti-CD24-CAR against Ovarian Cancer

por Klapdor, Rüdiger, Wang, Shuo, Morgan, Michael, Dörk, Thilo, Hacker, Ulrich, Hillemanns, Peter, Büning, Hildegard, Schambach, Axel
Publicado 2019

NK Cell-Mediated Eradication of Ovarian Cancer Cells with a Novel Chimeric Antigen Receptor Directed against CD44

por Klapdor, Rüdiger, Wang, Shuo, Morgan, Michael A., Zimmermann, Katharina, Hachenberg, Jens, Büning, Hildegard, Dörk, Thilo, Hillemanns, Peter, Schambach, Axel
Publicado 2021

Vector uncoating limits adeno-associated viral vector-mediated transduction of human dendritic cells and vector immunogenicity

por Rossi, Axel, Dupaty, Léa, Aillot, Ludovic, Zhang, Liang, Gallien, Célia, Hallek, Michael, Odenthal, Margarete, Adriouch, Sahil, Salvetti, Anna, Büning, Hildegard
Publicado 2019

Gene Editing for the Efficient Correction of a Recurrent COL7A1 Mutation in Recessive Dystrophic Epidermolysis Bullosa Keratinocytes

por Chamorro, Cristina, Mencía, Angeles, Almarza, David, Duarte, Blanca, Büning, Hildegard, Sallach, Jessica, Hausser, Ingrid, Del Río, Marcela, Larcher, Fernando, Murillas, Rodolfo
Publicado 2016

DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations

por Schnödt, Maria, Schmeer, Marco, Kracher, Barbara, Krüsemann, Christa, Espinosa, Laura Escalona, Grünert, Anja, Fuchsluger, Thomas, Rischmüller, Anja, Schleef, Martin, Büning, Hildegard
Publicado 2016

Adeno-associated virus type 2 (AAV2) uncoating is a stepwise process and is linked to structural reorganization of the nucleolus

por Sutter, Sereina O., Lkharrazi, Anouk, Schraner, Elisabeth M., Michaelsen, Kevin, Meier, Anita Felicitas, Marx, Jennifer, Vogt, Bernd, Büning, Hildegard, Fraefel, Cornel
Publicado 2022