Therapeutic Approaches Targeting PAX3-FOXO1 and Its Regulatory and Transcriptional Pathways in Rhabdomyosarcoma

por Nguyen, Thanh Hung, Barr, Frederic G.
Publicado 2018

The paternally imprinted DLK1-GTL2 locus is differentially methylated in embryonal and alveolar rhabdomyosarcomas

por SCHNEIDER, GABRIELA, BOWSER, MARK J., SHIN, DONG-MYUNG, BARR, FREDERIC G., RATAJCZAK, MARIUSZ Z.
Publicado 2013

Human rhabdomyosarcoma cells express functional pituitary and gonadal sex hormone receptors: Therapeutic implications

por PONIEWIERSKA-BARAN, AGATA, SCHNEIDER, GABRIELA, SUN, WENYUE, ABDELBASET-ISMAIL, AHMED, BARR, FREDERIC G., RATAJCZAK, MARIUSZ Z.
Publicado 2016

Human Rhabdomyosarcoma Cell Lines for Rhabdomyosarcoma Research: Utility and Pitfalls

por Hinson, Ashley R. P., Jones, Rosanne, Crose, Lisa E. S., Belyea, Brian C., Barr, Frederic G., Linardic, Corinne M.
Publicado 2013

Human rhabdomyosarcoma cells express functional erythropoietin receptor: Potential therapeutic implications

por PONIEWIERSKA-BARAN, AGATA, SUSZYNSKA, MALWINA, SUN, WENYUE, ABDELBASET-ISMAIL, AHMED, SCHNEIDER, GABRIELA, BARR, FREDERIC G., RATAJCZAK, MARIUSZ Z.
Publicado 2015

NanoString Digital Molecular Profiling of Protein and microRNA in Rhabdomyosarcoma

por Ahmed, Atif A., Farooqi, Midhat S., Habeebu, Sultan S., Gonzalez, Elizabeth, Flatt, Terrie G., Wilson, Ashley L., Barr, Frederic G.
Publicado 2022

RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas

por TARNOWSKI, MACIEJ, SCHNEIDER, GABRIELA, AMANN, GABRIELE, CLARK, GEOFFREY, HOUGHTON, PETER, BARR, FREDERIC G., KENNER, LUKAS, RATAJCZAK, MARIUSZ Z., KUCIA, MAGDA
Publicado 2012

Evidence of pioneer factor activity of an oncogenic fusion transcription factor

por Sunkel, Benjamin D., Wang, Meng, LaHaye, Stephanie, Kelly, Benjamin J., Fitch, James R., Barr, Frederic G., White, Peter, Stanton, Benjamin Z.
Publicado 2021

Rhabdomyosarcomas are oncogene addicted to the activation of AVIL

por Xie, Zhongqiu, Janczyk, Pawel L., Shi, Xinrui, Wang, Qiong, Singh, Sandeep, Cornelison, Robert, Xu, Jingjing, Mandell, James W., Barr, Frederic G., Li, Hui
Publicado 2022

Clonality and Evolutionary History of Rhabdomyosarcoma

por Chen, Li, Shern, Jack F., Wei, Jun S., Yohe, Marielle E., Song, Young K., Hurd, Laura, Liao, Hongling, Catchpoole, Daniel, Skapek, Stephen X., Barr, Frederic G., Hawkins, Douglas S., Khan, Javed
Publicado 2015

Piperacetazine Directly Binds to the PAX3::FOXO1 Fusion Protein and Inhibits Its Transcriptional Activity

por Nakazawa, Kay, Shaw, Taryn, Song, Young K., Kouassi-Brou, Marilyn, Molotkova, Anna, Tiwari, Purushottam B., Chou, Hsien-Chao, Wen, Xinyu, Wei, Jun S., Deniz, Emre, Toretsky, Jeffrey A., Keller, Charles, Barr, Frederic G., Khan, Javed, Üren, Aykut
Publicado 2023

Refinement of risk stratification for childhood rhabdomyosarcoma using FOXO1 fusion status in addition to established clinical outcome predictors: A report from the Children's Onco...

por Hibbitts, Emily, Chi, Yueh‐Yun, Hawkins, Douglas S., Barr, Frederic G., Bradley, Julie A., Dasgupta, Roshni, Meyer, William H., Rodeberg, David A., Rudzinski, Erin R., Spunt, Sheri L., Skapek, Stephen X., Wolden, Suzanne L., Arndt, Carola A. S.
Publicado 2019

Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity

por Manzella, Gabriele, Schreck, Leonie D., Breunis, Willemijn B., Molenaar, Jan, Merks, Hans, Barr, Frederic G., Sun, Wenyue, Römmele, Michaela, Zhang, Luduo, Tchinda, Joelle, Ngo, Quy A., Bode, Peter, Delattre, Olivier, Surdez, Didier, Rekhi, Bharat, Niggli, Felix K., Schäfer, Beat W., Wachtel, Marco
Publicado 2020

Phase I Clinical Trial of an Autologous Dendritic Cell Vaccine Against HER2 Shows Safety and Preliminary Clinical Efficacy

por Maeng, Hoyoung M., Moore, Brittni N., Bagheri, Hadi, Steinberg, Seth M., Inglefield, Jon, Dunham, Kim, Wei, Wei-Zen, Morris, John C., Terabe, Masaki, England, Lee C., Roberson, Brenda, Rosing, Douglas, Sachdev, Vandana, Pack, Svetlana D., Miettinen, Markku M., Barr, Frederic G., Weiner, Louis M., Panch, Sandhya, Stroncek, David F., Wood, Lauren V., Berzofsky, Jay A.
Publicado 2021