Implications of HIV-1 Nef for “Shock and Kill” Strategies to Eliminate Latent Viral Reservoirs

por Kuang, Xiaomei T., Brockman, Mark A.
Publicado 2018

Challenges and Opportunities for T-Cell-Mediated Strategies to Eliminate HIV Reservoirs

por Brockman, Mark A., Jones, R. Brad, Brumme, Zabrina L.
Publicado 2015

Brockman, M.A., et al., Human Leukocyte Antigen (HLA) Class I Down-Regulation by Human Immunodeficiency Virus Type 1 Negative Factor (HIV-1 Nef): What Might We Learn From Natural S...

por Mwimanzi, Philip, Markle, Tristan J., Ueno, Takamasa, Brockman, Mark A.
Publicado 2012

Human Leukocyte Antigen (HLA) Class I Down-Regulation by Human Immunodeficiency Virus Type 1 Negative Factor (HIV-1 Nef): What Might We Learn From Natural Sequence Variants?

por Mwimanzi, Philip, Markle, Tristan J., Ueno, Takamasa, Brockman, Mark A.
Publicado 2012

Diagnostic Accuracy of the HemoCue Hb 301, STAT-Site M(Hgb) and URIT-12 Point-of-Care Hemoglobin Meters in a Central Laboratory and a Community Based Clinic in Durban, South Africa

por Jaggernath, Manjeetha, Naicker, Rumallen, Madurai, Savathree, Brockman, Mark A., Ndung’u, Thumbi, Gelderblom, Huub C.
Publicado 2016

Quantitative Effect of Suboptimal Codon Usage on Translational Efficiency of mRNA Encoding HIV-1 gag in Intact T Cells

por Ngumbela, Kholiswa C., Ryan, Kieran P., Sivamurthy, Rohini, Brockman, Mark A., Gandhi, Rajesh T., Bhardwaj, Nina, Kavanagh, Daniel G.
Publicado 2008

Identification of Novel HIV-1 Latency-Reversing Agents from a Library of Marine Natural Products

por Richard, Khumoekae, Williams, David E., de Silva, E. Dilip, Brockman, Mark A., Brumme, Zabrina L., Andersen, Raymond J., Tietjen, Ian
Publicado 2018

HIV-1 subtype C Nef-mediated SERINC5 down-regulation significantly contributes to overall Nef activity

por Naicker, Delon, Sonela, Nelson, Jin, Steven W., Mulaudzi, Takalani, Ojwach, Doty, Reddy, Tarylee, Brockman, Mark A., Brumme, Zabrina L., Ndung’u, Thumbi, Mann, Jaclyn K.
Publicado 2023

Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences

por Mahiti, Macdonald, Toyoda, Mako, Jia, Xiaofei, Kuang, Xiaomei T., Mwimanzi, Francis, Mwimanzi, Philip, Walker, Bruce D., Xiong, Yong, Brumme, Zabrina L., Brockman, Mark A., Ueno, Takamasa
Publicado 2016

Longitudinal within-host evolution of HIV Nef-mediated CD4, HLA and SERINC5 downregulation activity: a case study

por Sudderuddin, Hanwei, Kinloch, Natalie N., Jin, Steven W., Miller, Rachel L., Jones, Bradley R., Brumme, Chanson J., Joy, Jeffrey B., Brockman, Mark A., Brumme, Zabrina L.
Publicado 2020

Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity

por Jin, Steven W., Alsahafi, Nirmin, Kuang, Xiaomei T., Swann, Shayda A., Toyoda, Mako, Göttlinger, Heinrich, Walker, Bruce D., Ueno, Takamasa, Finzi, Andrés, Brumme, Zabrina L., Brockman, Mark A.
Publicado 2019

African-led health research and capacity building- is it working?

por Kasprowicz, Victoria O., Chopera, Denis, Waddilove, Kim Darley, Brockman, Mark A., Gilmour, Jill, Hunter, Eric, Kilembe, William, Karita, Etienne, Gaseitsiwe, Simani, Sanders, Eduard J., Ndung’u, Thumbi
Publicado 2020

Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants

por Ogunshola, Funsho, Anmole, Gursev, Miller, Rachel L., Goering, Emily, Nkosi, Thandeka, Muema, Daniel, Mann, Jaclyn, Ismail, Nasreen, Chopera, Denis, Ndung’u, Thumbi, Brockman, Mark A., Ndhlovu, Zaza M
Publicado 2018

Attenuation of multiple Nef functions in HIV-1 elite controllers

por Mwimanzi, Philip, Markle, Tristan J, Martin, Eric, Ogata, Yoko, Kuang, Xiaomei T, Tokunaga, Michiyo, Mahiti, Macdonald, Pereyra, Florencia, Miura, Toshiyuki, Walker, Bruce D, Brumme, Zabrina L, Brockman, Mark A, Ueno, Takamasa
Publicado 2013

Phylogenetic approach to recover integration dates of latent HIV sequences within-host

por Jones, Bradley R., Kinloch, Natalie N., Horacsek, Joshua, Ganase, Bruce, Harris, Marianne, Harrigan, P. Richard, Jones, R. Brad, Brockman, Mark A., Joy, Jeffrey B., Poon, Art F. Y., Brumme, Zabrina L.
Publicado 2018

High Levels of Dual-Class Drug Resistance in HIV-Infected Children Failing First-Line Antiretroviral Therapy in Southern Ethiopia

por Tadesse, Birkneh Tilahun, Kinloch, Natalie N., Baraki, Bemuluyigza, Lapointe, Hope R., Cobarrubias, Kyle D., Brockman, Mark A., Brumme, Chanson J., Foster, Byron A., Jerene, Degu, Makonnen, Eyasu, Aklillu, Eleni, Brumme, Zabrina L.
Publicado 2018

HIV and HCV Cooperatively Promote Hepatic Fibrogenesis via Induction of Reactive Oxygen Species and NFκB

por Lin, Wenyu, Wu, Guoyang, Li, Shaoyong, Weinberg, Ethan M., Kumthip, Kattareeya, Peng, Lee F., Méndez-Navarro, Jorge, Chen, Wen-Chi, Jilg, Nikolaus, Zhao, Hong, Goto, Kaku, Zhang, Leiliang, Brockman, Mark A., Schuppan, Detlef, Chung, Raymond T.
Publicado 2011

Viral adaptation to immune selection pressure by HLA class I–restricted CTL responses targeting epitopes in HIV frameshift sequences

por Berger, Christoph T., Carlson, Jonathan M., Brumme, Chanson J., Hartman, Kari L., Brumme, Zabrina L., Henry, Leah M., Rosato, Pamela C., Piechocka-Trocha, Alicja, Brockman, Mark A., Harrigan, P. Richard, Heckerman, David, Kaufmann, Daniel E., Brander, Christian
Publicado 2010

Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5

por Jin, Steven W., Mwimanzi, Francis M., Mann, Jaclyn K., Bwana, Mwebesa Bosco, Lee, Guinevere Q., Brumme, Chanson J., Hunt, Peter W., Martin, Jeff N., Bangsberg, David R., Ndung’u, Thumbi, Brumme, Zabrina L., Brockman, Mark A.
Publicado 2020

No Evidence for Selection of HIV-1 with Enhanced Gag-Protease or Nef Function among Breakthrough Infections in the CAPRISA 004 Tenofovir Microbicide Trial

por Chopera, Denis R., Mann, Jaclyn K., Mwimanzi, Philip, Omarjee, Saleha, Kuang, Xiaomei T., Ndabambi, Nonkululeko, Goodier, Sarah, Martin, Eric, Naranbhai, Vivek, Karim, Salim Abdool, Karim, Quarraisha Abdool, Brumme, Zabrina L., Ndung'u, Thumbi, Williamson, Carolyn, Brockman, Mark A.
Publicado 2013