Trastuzumab Induces an Immediate, Transient Volume Increase in Humans: A Randomised Placebo-Controlled Trial

por Reijers, Joannes A.A., Burggraaf, Jacobus
Publicado 2015

Under‐representation of elderly in clinical trials: An analysis of the initial approval documents in the Food and Drug Administration database

por Ruiter, Rikje, Burggraaf, Jacobus, Rissmann, Robert
Publicado 2019

Remarkable Pharmacokinetics of Monoclonal Antibodies: A Quest for an Explanation

por Reijers, Joannes A. A., Moerland, Matthijs, Burggraaf, Jacobus
Publicado 2016

Gender differences in clinical registration trials: is there a real problem?

por Labots, Geert, Jones, Aubrey, de Visser, Saco J., Rissmann, Robert, Burggraaf, Jacobus
Publicado 2018

Effect of short‐term fasting on electrocardiographic parameters

por van der Stuijt, Willeke, Gal, Pim, Kemme, Michiel J. B., Burggraaf, Jacobus
Publicado 2019

A two-step deconvolution-analysis-informed population pharmacodynamic modeling approach for drugs targeting pulsatile endogenous compounds

por van Esdonk, Michiel J., Burggraaf, Jacobus, van der Graaf, Piet H., Stevens, Jasper
Publicado 2017

Model informed quantification of the feed‐forward stimulation of growth hormone by growth hormone‐releasing hormone

por van Esdonk, Michiel J., Burggraaf, Jacobus, van der Graaf, Piet H., Stevens, Jasper
Publicado 2020

An exploratory study with an adaptive continuous intravenous furosemide regimen in neonates treated with extracorporeal membrane oxygenation

por van der Vorst, Maria MJ, den Hartigh, Jan, Wildschut, Enno, Tibboel, Dick, Burggraaf, Jacobus
Publicado 2007

The effect of repeated methotrexate injections on the quality of life of children with rheumatic diseases

por Jacobse, Justin, ten Voorde, Wouter, Rissmann, Robert, Burggraaf, Jacobus, ten Cate, Rebecca, Schrier, Lenneke
Publicado 2018

Novel SGLT2 inhibitor: first‐in‐man studies of antisense compound is associated with unexpected renal effects

por van Meer, Leonie, van Dongen, Marloes, Moerland, Matthijs, de Kam, Marieke, Cohen, Adam, Burggraaf, Jacobus
Publicado 2017

Quantification of the endogenous growth hormone and prolactin lowering effects of a somatostatin-dopamine chimera using population PK/PD modeling

por van Esdonk, Michiel J., Burggraaf, Jacobus, Dehez, Marion, van der Graaf, Piet H., Stevens, Jasper
Publicado 2020

Stability analysis of clustering of Norris’ visual analogue scale: Applying the consensus clustering approach

por Guan, Zheng, Chen, X. Gregory, Hay, Justin, van Gerven, Joop, Burggraaf, Jacobus, de Kam, Marieke
Publicado 2021

Potential Influence of Endothelial Adsorption on the Delayed Time to Maximum Concentration of Biopharmaceuticals

por Reijers, Joannes A. A., Dane, Martijn J. C., van Zonneveld, Anton Jan, Burggraaf, Jacobus, Moerland, Matthijs
Publicado 2017

Adverse immunostimulation caused by impurities: The dark side of biopharmaceuticals

por Reijers, Joannes A. A., Malone, Karen E., Bajramovic, Jeffrey J., Verbeek, Richard, Burggraaf, Jacobus, Moerland, Matthijs
Publicado 2019

PK/PD modeling of 5‐hydroxytryptophan (5‐HTP) challenge test with cortisol measurement in serum and saliva

por Guan, Zheng, Jacobs, Gabriel, van Pelt, Hans, Van Gerven, Joop M.A., Burggraaf, Jacobus, Zhao, Wei
Publicado 2020

The effect of food and formulation on the population pharmacokinetics of cholesteryl ester transferase protein inhibitor DRL‐17822 in healthy male volunteers

por Goulooze, Sebastiaan C., Kruithof, Annelieke C., Alikunju, Shanavas, Gautam, Anirudh, Burggraaf, Jacobus, Kamerling, Ingrid M.C., Stevens, Jasper
Publicado 2020

Stimulation programs for pediatric drug research – do children really benefit?

por Boots, Isabelle, Sukhai, Rám N., Klein, Richard H., Holl, Robert A., Wit, Jan M., Cohen, Adam F., Burggraaf, Jacobus
Publicado 2007

The Oral Pheneticillin Absorption Test: An Accurate Method to Identify Patients with Inadequate Oral Pheneticillin Absorption

por Dijkmans, Anneke C., Kweekel, Dinemarie M., van Dissel, Jaap T., van Esdonk, Michiel J., Kamerling, Ingrid M. C., Burggraaf, Jacobus
Publicado 2019

The Effect of a 13-Valent Conjugate Pneumococcal Vaccine on Circulating Antibodies Against Oxidized LDL and Phosphorylcholine in Man, A Randomized Placebo-Controlled Clinical Trial

por Grievink, Hendrika W., Gal, Pim, Ozsvar Kozma, Maria, Klaassen, Erica S., Kuiper, Johan, Burggraaf, Jacobus, Binder, Christoph J., Moerland, Matthijs
Publicado 2020

Dose escalations in phase I studies: Feasibility of interpreting blinded pharmacodynamic data

por Hassing, Gerardus J., van Esdonk, Michiel J., van Westen, Gerard J. P., Cohen, Adam F., Burggraaf, Jacobus, Gal, Pim
Publicado 2022