Forkhead-Box-P3 Gene Transfer in Human CD4(+) T Conventional Cells for the Generation of Stable and Efficient Regulatory T Cells, Suitable for Immune Modulatory Therapy

por Passerini, Laura, Bacchetta, Rosa
Publicado 2017

Thymic origins of autoimmunity—lessons from inborn errors of immunity

por Bacchetta, Rosa, Weinberg, Kenneth
Publicado 2021

Editorial: IPEX 2020: An Expanding Disease Spectrum and Novel Precision Therapies

por Bacchetta, Rosa, Chatila, Talal
Publicado 2022

Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-Linked Syndrome: A Paradigm of Immunodeficiency with Autoimmunity

por Barzaghi, Federica, Passerini, Laura, Bacchetta, Rosa
Publicado 2012

Rare immune diseases paving the road for genome editing-based precision medicine

por Pavel-Dinu, Mara, Borna, Simon, Bacchetta, Rosa
Publicado 2023

Towards gene therapy for IPEX syndrome

por Borna, Simon, Lee, Esmond, Sato, Yohei, Bacchetta, Rosa
Publicado 2022

Type 1 regulatory T (Tr1) cells: from the bench to the bedside

por Gregori, Silvia, Bacchetta, Rosa, Battaglia, Manuela, Roncarolo, Maria Grazia
Publicado 2012

Analyses of thymocyte commitment to regulatory T cell lineage in thymus of healthy subjects and patients with 22q11.2 deletion syndrome

por Borna, Simon, Dejene, Beruh, Lakshmanan, Uma, Schulze, Janika, Weinberg, Kenneth, Bacchetta, Rosa
Publicado 2023

Gene/Cell Therapy Approaches for Immune Dysregulation Polyendocrinopathy Enteropathy X-Linked Syndrome

por Passerini, Laura, Santoni de Sio, Francesca R., Porteus, Matthew H., Bacchetta, Rosa
Publicado 2014

Case Study: Mechanism for Increased Follicular Helper T Cell Development in Activated PI3K Delta Syndrome

por Thauland, Timothy J., Pellerin, Laurence, Ohgami, Robert S., Bacchetta, Rosa, Butte, Manish J.
Publicado 2019

Co-Expression of FOXP3FL and FOXP3Δ2 Isoforms Is Required for Optimal Treg-Like Cell Phenotypes and Suppressive Function

por Sato, Yohei, Liu, Jessica, Lee, Esmond, Perriman, Rhonda, Roncarolo, Maria Grazia, Bacchetta, Rosa
Publicado 2021

APVO210: A Bispecific Anti-CD86-IL-10 Fusion Protein (ADAPTIR™) to Induce Antigen-Specific T Regulatory Type 1 Cells

por Pellerin, Laurence, Chen, Ping, Gregori, Silvia, Hernandez-Hoyos, Gabriela, Bacchetta, Rosa, Roncarolo, Maria Grazia
Publicado 2018

Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells

por Magnani, Chiara F, Alberigo, Giada, Bacchetta, Rosa, Serafini, Giorgia, Andreani, Marco, Roncarolo, Maria Grazia, Gregori, Silvia
Publicado 2011

Autoantibodies to Harmonin and Villin Are Diagnostic Markers in Children with IPEX Syndrome

por Lampasona, Vito, Passerini, Laura, Barzaghi, Federica, Lombardoni, Carlo, Bazzigaluppi, Elena, Brigatti, Cristina, Bacchetta, Rosa, Bosi, Emanuele
Publicado 2013

A novel FOXP3 knockout-humanized mouse model for pre-clinical safety and efficacy evaluation of Treg-like cell products

por Sato, Yohei, Nathan, Abinaya, Shipp, Suzette, Wright, John Fraser, Tate, Keri Marie, Wani, Prachi, Roncarolo, Maria-Grazia, Bacchetta, Rosa
Publicado 2023

Identification of STAT5A and STAT5B Target Genes in Human T Cells

por Kanai, Takahiro, Seki, Scott, Jenks, Jennifer A., Kohli, Arunima, Kawli, Trupti, Martin, Dorrelyn Patacsil, Snyder, Michael, Bacchetta, Rosa, Nadeau, Kari C.
Publicado 2014

Neutralizing Anti-Cytokine Autoantibodies Against Interferon-α in Immunodysregulation Polyendocrinopathy Enteropathy X-Linked

por Rosenberg, Jacob M., Maccari, Maria E., Barzaghi, Federica, Allenspach, Eric J., Pignata, Claudio, Weber, Giovanna, Torgerson, Troy R., Utz, Paul J., Bacchetta, Rosa
Publicado 2018

An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells

por Gregori, Silvia, Mangia, Patrizia, Bacchetta, Rosa, Tresoldi, Eleonora, Kolbinger, Frank, Traversari, Catia, Carballido, Josè M., de Vries, Jan E., Korthäuer, Ulf, Roncarolo, Maria-Grazia
Publicado 2005

Human‐engineered Treg‐like cells suppress FOXP3‐deficient T cells but preserve adaptive immune responses in vivo

por Sato, Yohei, Passerini, Laura, Piening, Brian D, Uyeda, Molly Javier, Goodwin, Marianne, Gregori, Silvia, Snyder, Michael P, Bertaina, Alice, Roncarolo, Maria‐Grazia, Bacchetta, Rosa
Publicado 2020

FOXP3 TSDR Measurement Could Assist Variant Classification and Diagnosis of IPEX Syndrome

por Wyatt, Rebecca C., Olek, Sven, De Franco, Elisa, Samans, Bjoern, Patel, Kashyap, Houghton, Jayne, Walter, Steffi, Schulze, Janika, Bacchetta, Rosa, Hattersley, Andrew T., Flanagan, Sarah E., Johnson, Matthew B.
Publicado 2023