Pathophysiological consequences and benefits of HFE mutations: 20 years of research

por Hollerer, Ina, Bachmann, André, Muckenthaler, Martina U.
Publicado 2017

On the role of the MAGUK proteins encoded by Drosophila varicose during embryonic and postembryonic development

por Bachmann, André, Draga, Margarete, Grawe, Ferdi, Knust, Elisabeth
Publicado 2008

Withaferin A Inhibits STAT3 and Induces Tumor Cell Death in Neuroblastoma and Multiple Myeloma

por Yco, Lisette P, Mocz, Gabor, Opoku-Ansah, John, Bachmann, André S
Publicado 2014

Harmine, a dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) inhibitor induces caspase-mediated apoptosis in neuroblastoma

por Uhl, Katie L., Schultz, Chad R., Geerts, Dirk, Bachmann, André S.
Publicado 2018

Effect of sulfasalazine on human neuroblastoma: analysis of sepiapterin reductase (SPR) as a new therapeutic target

por Yco, Lisette P., Geerts, Dirk, Mocz, Gabor, Koster, Jan, Bachmann, André S.
Publicado 2015

Polyamine Biosynthetic Pathway as a Drug Target for Osteosarcoma Therapy

por Weicht, Rebecca R., Schultz, Chad R., Geerts, Dirk, Uhl, Katie L., Bachmann, André S.
Publicado 2018

DFMO/eflornithine inhibits migration and invasion downstream of MYCN and involves p27(Kip1) activity in neuroblastoma

por KOOMOA, DANA-LYNN T., GEERTS, DIRK, LANGE, INGO, KOSTER, JAN, PEGG, ANTHONY E., FEITH, DAVID J., BACHMANN, ANDRÉ S.
Publicado 2013

New K50R mutant mouse models reveal impaired hypusination of eif5a2 with alterations in cell metabolite landscape

por Schultz, Chad R., Sheldon, Ryan D., Xie, Huirong, Demireva, Elena Y., Uhl, Katie L., Agnew, Dalen W., Geerts, Dirk, Bachmann, André S.
Publicado 2023

Structure and Enzymatic Activity of an Intellectual Disability-Associated Ornithine Decarboxylase Variant, G84R

por Zhou, X. Edward, Schultz, Chad R., Suino Powell, Kelly, Henrickson, Amy, Lamp, Jared, Brunzelle, Joseph S., Demeler, Borries, Vega, Irving E., Bachmann, André S., Melcher, Karsten
Publicado 2022

Combined Plasma and Urinary Metabolomics Uncover Metabolic Perturbations Associated with Severe Respiratory Syncytial Viral Infection and Future Development of Asthma in Infant Pat...

por Teoh, Shao Thing, Leimanis-Laurens, Mara L., Comstock, Sarah S., Winters, John W., Vandenbosch, Nikita L., Prokop, Jeremy W., Bachmann, André S., Lunt, Sophia Y., Rajasekaran, Surender
Publicado 2022

Ornithine decarboxylase as a therapeutic target for endometrial cancer

por Kim, Hong Im, Schultz, Chad R., Buras, Andrea L., Friedman, Elizabeth, Fedorko, Alyssa, Seamon, Leigh, Chandramouli, Gadisetti V. R., Maxwell, G. Larry, Bachmann, André S., Risinger, John I.
Publicado 2017

Gene expression signatures identify paediatric patients with multiple organ dysfunction who require advanced life support in the intensive care unit

por Shankar, Rama, Leimanis, Mara L., Newbury, Patrick A., Liu, Ke, Xing, Jing, Nedveck, Derek, Kort, Eric J., Prokop, Jeremy W, Zhou, Guoli, Bachmann, André S, Chen, Bin, Rajasekaran, Surender
Publicado 2020

Expanding the phenotype: Four new cases and hope for treatment in Bachmann‐Bupp syndrome

por VanSickle, Elizabeth A., Michael, Julianne, Bachmann, André S., Rajasekaran, Surender, Prokop, Jeremy W., Kuzniecky, Ruben, Hofstede, Floris C., Steindl, Katharina, Rauch, Anita, Lipson, Mark H., Bupp, Caleb P.
Publicado 2021

Emerging Role of ODC1 in Neurodevelopmental Disorders and Brain Development

por Prokop, Jeremy W., Bupp, Caleb P., Frisch, Austin, Bilinovich, Stephanie M., Campbell, Daniel B., Vogt, Daniel, Schultz, Chad R., Uhl, Katie L., VanSickle, Elizabeth, Rajasekaran, Surender, Bachmann, André S.
Publicado 2021

Selective targeting of CD38 hydrolase and cyclase activity as an approach to immunostimulation

por Benton, Thomas Z., Mills, Catherine M., Turner, Jonathan M., Francis, Megan J., Solomon, Dalan J., Burger, Pieter B., Peterson, Yuri K., Dolloff, Nathan G., Bachmann, André S., Woster, Patrick M.
Publicado 2021

Repurposing eflornithine to treat a patient with a rare ODC1 gain-of-function variant disease

por Rajasekaran, Surender, Bupp, Caleb P, Leimanis-Laurens, Mara, Shukla, Ankit, Russell, Christopher, Junewick, Joseph, Gleason, Emily, VanSickle, Elizabeth A, Edgerly, Yvonne, Wittmann, Bryan M, Prokop, Jeremy W, Bachmann, André S
Publicado 2021

Two New Cases of Bachmann–Bupp Syndrome Identified through the International Center for Polyamine Disorders

por Michael, Julianne, VanSickle, Elizabeth, Vipond, Marlie, Dalman, Abby, Prokop, Jeremy, Schwartz, Charles E., Rajasekaran, Surender, Bachmann, André S., Barth, Magalie, Prouteau, Clément, Almagor, Yotam, Berkun, Lina, Alterescu, Gheona, Bupp, Caleb P.
Publicado 2023

A Phase I Trial of DFMO Targeting Polyamine Addiction in Patients with Relapsed/Refractory Neuroblastoma

por Saulnier Sholler, Giselle L., Gerner, Eugene W., Bergendahl, Genevieve, MacArthur, Robert B., VanderWerff, Alyssa, Ashikaga, Takamaru, Bond, Jeffrey P., Ferguson, William, Roberts, William, Wada, Randal K., Eslin, Don, Kraveka, Jacqueline M., Kaplan, Joel, Mitchell, Deanna, Parikh, Nehal S., Neville, Kathleen, Sender, Leonard, Higgins, Timothy, Kawakita, Masao, Hiramatsu, Kyoko, Moriya, Shun-suke, Bachmann, André S.
Publicado 2015