Virus-mediated EpoR76E gene therapy preserves vision in a glaucoma model by modulating neuroinflammation and decreasing oxidative stress

por Hines-Beard, Jessica, Bond, Wesley S., Backstrom, Jon R., Rex, Tonia S.
Publicado 2016

Retinal oxidative stress activates the NRF2/ARE pathway: An early endogenous protective response to ocular hypertension

por Naguib, Sarah, Backstrom, Jon R., Gil, Melanie, Calkins, David J., Rex, Tonia S.
Publicado 2021

Optimization of S. aureus dCas9 and CRISPRi Elements for a Single Adeno-Associated Virus that Targets an Endogenous Gene

por Backstrom, Jon R., Sheng, Jinsong, Wang, Michael C., Bernardo-Colón, Alexandra, Rex, Tonia S.
Publicado 2020

NRF2/ARE mediated antioxidant response to glaucoma: role of glia and retinal ganglion cells

por Naguib, Sarah, Backstrom, Jon R., Artis, Elisabeth, Ghose, Purnima, Stahl, Amy, Hardin, Rachael, Haider, Ameer A., Ang, John, Calkins, David J., Rex, Tonia S.
Publicado 2023

Intraocular Sustained Release of EPO-R76E Mitigates Glaucoma Pathogenesis by Activating the NRF2/ARE Pathway

por Naguib, Sarah, DeJulius, Carlisle R., Backstrom, Jon R., Haider, Ameer A., Ang, John M., Boal, Andrew M., Calkins, David J., Duvall, Craig L., Rex, Tonia S.
Publicado 2023