Intra- and inter-molecular recombination of mitochondrial DNA after in vivo induction of multiple double-strand breaks

por Bacman, Sandra R., Williams, Sion L., Moraes, Carlos T.
Publicado 2009

Organ-specific shifts in mtDNA heteroplasmy following systemic delivery of a mitochondria-targeted restriction endonuclease

por Bacman, Sandra R., Williams, Sion L., Garcia, Sofia, Moraes, Carlos T.
Publicado 2010

Manipulation of mtDNA heteroplasmy in all striated muscles of newborn mice by AAV9-mediated delivery of a mitochondria targeted restriction endonuclease

por Bacman, Sandra R., Williams, Sion L., Duan, Dongsheng, Moraes, Carlos T.
Publicado 2011

The mitochondrial DNA polymerase gamma degrades linear DNA fragments precluding the formation of deletions

por Nissanka, Nadee, Bacman, Sandra R., Plastini, Melanie J., Moraes, Carlos T.
Publicado 2018

Precise and simultaneous quantification of mitochondrial DNA heteroplasmy and copy number by digital PCR

por Shoop, Wendy K., Gorsuch, Cassandra L., Bacman, Sandra R., Moraes, Carlos T.
Publicado 2022

Specific elimination of mutant mitochondrial genomes in patient–derived cells by mitoTALENs

por Bacman, Sandra R., Williams, Siôn L., Pinto, Milena, Peralta, Susana, Moraes, Carlos T.
Publicado 2013

Myopathy reversion in mice after restauration of mitochondrial complex I

por Pereira, Claudia V, Peralta, Susana, Arguello, Tania, Bacman, Sandra R, Diaz, Francisca, Moraes, Carlos T
Publicado 2020

mitoTev‐TALE: a monomeric DNA editing enzyme to reduce mutant mitochondrial DNA levels

por Pereira, Claudia V, Bacman, Sandra R, Arguello, Tania, Zekonyte, Ugne, Williams, Sion L, Edgell, David R, Moraes, Carlos T
Publicado 2018

Mitochondrial targeted meganuclease as a platform to eliminate mutant mtDNA in vivo

por Zekonyte, Ugne, Bacman, Sandra R., Smith, Jeff, Shoop, Wendy, Pereira, Claudia V., Tomberlin, Ginger, Stewart, James, Jantz, Derek, Moraes, Carlos T.
Publicado 2021