Development of potent in vivo mutagenesis plasmids with broad mutational spectra

por Badran, Ahmed H., Liu, David R.
Publicado 2015

Continuous bioactivity-dependent evolution of an antibiotic biosynthetic pathway

por Johnston, Chad W., Badran, Ahmed H., Collins, James J.
Publicado 2020

A system for the continuous directed evolution of proteases rapidly reveals drug-resistance mutations

por Dickinson, Bryan C., Packer, Michael S., Badran, Ahmed H., Liu, David R.
Publicado 2014

Continuous directed evolution of proteins with improved soluble expression

por Wang, Tina, Badran, Ahmed H., Huang, Tony P., Liu, David R.
Publicado 2018

Orthogonal translation enables heterologous ribosome engineering in E. coli

por Kolber, Natalie S., Fattal, Ranan, Bratulic, Sinisa, Carver, Gavriela D., Badran, Ahmed H.
Publicado 2021

Directed evolution of rRNA improves translation kinetics and recombinant protein yield

por Liu, Fan, Bratulić, Siniša, Costello, Alan, Miettinen, Teemu P., Badran, Ahmed H.
Publicado 2021

Negative selection and stringency modulation in phage-assisted constinuous evolution

por Carlson, Jacob C., Badran, Ahmed H., Guggiana-Nilo, Drago A., Liu, David R.
Publicado 2014

Multiplex suppression of four quadruplet codons via tRNA directed evolution

por DeBenedictis, Erika A., Carver, Gavriela D., Chung, Christina Z., Söll, Dieter, Badran, Ahmed H.
Publicado 2021

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

por Gaudelli, Nicole M., Komor, Alexis C., Rees, Holly A., Packer, Michael S., Badran, Ahmed H., Bryson, David I., Liu, David R.
Publicado 2017

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity

por Komor, Alexis C., Zhao, Kevin T., Packer, Michael S., Gaudelli, Nicole M., Waterbury, Amanda L., Koblan, Luke W., Kim, Y. Bill, Badran, Ahmed H., Liu, David R.
Publicado 2017

Continuous directed evolution of DNA-binding proteins to improve TALEN specificity

por Hubbard, Basil P., Badran, Ahmed H., Zuris, John A., Guilinger, John P., Davis, Kevin M., Chen, Liwei, Tsai, Shengdar Q., Sander, Jeffry D., Joung, J. Keith, Liu, David R.
Publicado 2015

Continuous evolution of B. thuringiensis toxins overcomes insect resistance

por Badran, Ahmed H., Guzov, Victor M., Huai, Qing, Kemp, Melissa M., Vishwanath, Prashanth, Kain, Wendy, Nance, Autumn M., Evdokimov, Artem, Moshiri, Farhad, Turner, Keith H., Wang, Ping, Malvar, Thomas, Liu, David R.
Publicado 2016