Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations

por Baell, Jonathan B., Nissink, J. Willem M.
Publicado 2017

Strategies for the Development of Conotoxins as New Therapeutic Leads

por Brady, Ryan M., Baell, Jonathan B., Norton, Raymond S.
Publicado 2013

Novel Perspectives on the Design and Development of a Long-Acting Subcutaneous Raltegravir Injection for Treatment of HIV—In Vitro and In Vivo Evaluation

por Abd-Ellah, Heba S., Mudududdla, Ramesh, Carter, Glen P., Baell, Jonathan B.
Publicado 2023

Design, Development, and Optimisation of Smart Linker Chemistry for Targeted Colonic Delivery—In Vitro Evaluation

por Abd-Ellah, Heba S., Mudududdla, Ramesh, Carter, Glen P., Baell, Jonathan B.
Publicado 2023

FAF-Drugs3: a web server for compound property calculation and chemical library design

por Lagorce, David, Sperandio, Olivier, Baell, Jonathan B., Miteva, Maria A., Villoutreix, Bruno O.
Publicado 2015

AMPK protects endothelial cells against HSV-1 replication via inhibition of mTORC1 and ACC1

por Doshi, Heena, Spengler, Katrin, Godbole, Amod, Gee, Yi Sing, Baell, Jonathan, Oakhill, Jonathan S., Henke, Andreas, Heller, Regine
Publicado 2023

Correspondence: Reply to ‘Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury’

por Qin, Cheng Xue, May, Lauren T., Sexton, Patrick M., DeBono, Aaron J., Baell, Jonathan B., Christopoulos, Arthur, Ritchie, Rebecca H.
Publicado 2018

Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoceptor antagonist activity in isolated preparations of rat vas deferens, for translatio...

por Mathiew, Mitch, Dennis, Belinda M, Bennetts, Felix, Su, N N Eunice, Nguyen, Nghi, Botteon, Antony, Baell, Jonathan B, Ventura, Sabatino
Publicado 2020

Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign

por Sykes, Melissa L., Baell, Jonathan B., Kaiser, Marcel, Chatelain, Eric, Moawad, Sarah R., Ganame, Danny, Ioset, Jean-Robert, Avery, Vicky M.
Publicado 2012

Correction: Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign

por Sykes, Melissa L., Baell, Jonathan B., Kaiser, Marcel, Chatelain, Eric, Moawad, Sarah R., Ganame, Danny, Ioset, Jean-Robert, Avery, Vicky M.
Publicado 2013

Selective inhibition of apicoplast tryptophanyl-tRNA synthetase causes delayed death in Plasmodium falciparum

por Pasaje, Charisse Flerida A., Cheung, Vanessa, Kennedy, Kit, Lim, Erin E., Baell, Jonathan B., Griffin, Michael D. W., Ralph, Stuart A.
Publicado 2016

Selenophene and thiophene-core estrogen receptor ligands that inhibit motility and development of parasitic stages of Haemonchus contortus

por Preston, Sarah, Luo, Junjie, Zhang, Yuezhou, Jabbar, Abdul, Crawford, Simon, Baell, Jonathan, Hofmann, Andreas, Hu, Min, Zhou, Hai-Bing, Gasser, Robin B.
Publicado 2016

ω-Conotoxin GVIA Mimetics that Bind and Inhibit Neuronal Ca(v)2.2 Ion Channels

por Tranberg, Charlotte Elisabet, Yang, Aijun, Vette, Irina, McArthur, Jeffrey R., Baell, Jonathan B., Lewis, Richard J., Tuck, Kellie L., Duggan, Peter J.
Publicado 2012

Development of 1,2,4-Oxadiazole Antimicrobial Agents to Treat Enteric Pathogens within the Gastrointestinal Tract

por Pitcher, Noel P., Harjani, Jitendra R., Zhao, Yichao, Jin, Jianwen, Knight, Daniel R., Li, Lucy, Putsathit, Papanin, Riley, Thomas V., Carter, Glen P., Baell, Jonathan B.
Publicado 2022

A practical Java tool for small-molecule compound appraisal

por Amani, Parisa, Sneyd, Todd, Preston, Sarah, Young, Neil D, Mason, Lyndel, Bailey, Ulla-Maja, Baell, Jonathan, Camp, David, Gasser, Robin B, Gorse, Alain-Dominique, Taylor, Paul, Hofmann, Andreas
Publicado 2015

Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations

por Choi, Jaesung P., Wang, Rui, Yang, Xi, Wang, Xian, Wang, Lu, Ting, Ka Ka, Foley, Matthew, Cogger, Victoria, Yang, Zhuo, Liu, Feng, Han, Zhiming, Liu, Renjing, Baell, Jonathan, Zheng, Xiangjian
Publicado 2018

A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity

por Liang, Shuwei, Tran, Eric, Du, Xin, Dong, Jiajun, Sudholz, Harrison, Chen, Hao, Qu, Zihan, Huntington, Nicholas D., Babon, Jeffrey J., Kershaw, Nadia J., Zhang, Zhong-Yin, Baell, Jonathan B., Wiede, Florian, Tiganis, Tony
Publicado 2023

A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner

por Sutton, Selina K., Carter, Daniel R., Kim, Patrick, Tan, Owen, Arndt, Greg M., Zhang, Xu Dong, Baell, Jonathan, Noll, Benjamin D., Wang, Shudong, Kumar, Naresh, McArthur, Grant A., Cheung, Belamy B., Marshall, Glenn M.
Publicado 2016

Screening of the ‘Open Scaffolds’ collection from Compounds Australia identifies a new chemical entity with anthelmintic activities against different developmental stages of the ba...

por Preston, Sarah, Jiao, Yaqing, Baell, Jonathan B., Keiser, Jennifer, Crawford, Simon, Koehler, Anson V., Wang, Tao, Simpson, Moana M., Kaplan, Ray M., Cowley, Karla J., Simpson, Kaylene J., Hofmann, Andreas, Jabbar, Abdul, Gasser, Robin B.
Publicado 2017

Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors

por Dahlin, Jayme L., Nelson, Kathryn M., Strasser, Jessica M., Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena M., Organ, Shawna, Cuellar, Matthew, Singh, Gurpreet, Shrimp, Jonathan H., Nguyen, Nghi, Meier, Jordan L., Arrowsmith, Cheryl H., Brown, Peter J., Baell, Jonathan B., Walters, Michael A.
Publicado 2017