Seven Year Itch: Pan-Assay Interference Compounds (PAINS) in 2017—Utility and Limitations

por Baell, Jonathan B., Nissink, J. Willem M.
Publicado 2017

Strategies for the Development of Conotoxins as New Therapeutic Leads

por Brady, Ryan M., Baell, Jonathan B., Norton, Raymond S.
Publicado 2013

Novel Perspectives on the Design and Development of a Long-Acting Subcutaneous Raltegravir Injection for Treatment of HIV—In Vitro and In Vivo Evaluation

por Abd-Ellah, Heba S., Mudududdla, Ramesh, Carter, Glen P., Baell, Jonathan B.
Publicado 2023

Design, Development, and Optimisation of Smart Linker Chemistry for Targeted Colonic Delivery—In Vitro Evaluation

por Abd-Ellah, Heba S., Mudududdla, Ramesh, Carter, Glen P., Baell, Jonathan B.
Publicado 2023

FAF-Drugs3: a web server for compound property calculation and chemical library design

por Lagorce, David, Sperandio, Olivier, Baell, Jonathan B., Miteva, Maria A., Villoutreix, Bruno O.
Publicado 2015

Correspondence: Reply to ‘Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury’

por Qin, Cheng Xue, May, Lauren T., Sexton, Patrick M., DeBono, Aaron J., Baell, Jonathan B., Christopoulos, Arthur, Ritchie, Rebecca H.
Publicado 2018

Synthesis of 2-phenyl-5,6,7,8-tetrahydroquinoxaline derivatives and screening for P2X1-purinoceptor antagonist activity in isolated preparations of rat vas deferens, for translatio...

por Mathiew, Mitch, Dennis, Belinda M, Bennetts, Felix, Su, N N Eunice, Nguyen, Nghi, Botteon, Antony, Baell, Jonathan B, Ventura, Sabatino
Publicado 2020

Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign

por Sykes, Melissa L., Baell, Jonathan B., Kaiser, Marcel, Chatelain, Eric, Moawad, Sarah R., Ganame, Danny, Ioset, Jean-Robert, Avery, Vicky M.
Publicado 2012

Correction: Identification of Compounds with Anti-Proliferative Activity against Trypanosoma brucei brucei Strain 427 by a Whole Cell Viability Based HTS Campaign

por Sykes, Melissa L., Baell, Jonathan B., Kaiser, Marcel, Chatelain, Eric, Moawad, Sarah R., Ganame, Danny, Ioset, Jean-Robert, Avery, Vicky M.
Publicado 2013

Selective inhibition of apicoplast tryptophanyl-tRNA synthetase causes delayed death in Plasmodium falciparum

por Pasaje, Charisse Flerida A., Cheung, Vanessa, Kennedy, Kit, Lim, Erin E., Baell, Jonathan B., Griffin, Michael D. W., Ralph, Stuart A.
Publicado 2016

ω-Conotoxin GVIA Mimetics that Bind and Inhibit Neuronal Ca(v)2.2 Ion Channels

por Tranberg, Charlotte Elisabet, Yang, Aijun, Vette, Irina, McArthur, Jeffrey R., Baell, Jonathan B., Lewis, Richard J., Tuck, Kellie L., Duggan, Peter J.
Publicado 2012

Development of 1,2,4-Oxadiazole Antimicrobial Agents to Treat Enteric Pathogens within the Gastrointestinal Tract

por Pitcher, Noel P., Harjani, Jitendra R., Zhao, Yichao, Jin, Jianwen, Knight, Daniel R., Li, Lucy, Putsathit, Papanin, Riley, Thomas V., Carter, Glen P., Baell, Jonathan B.
Publicado 2022

A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity

por Liang, Shuwei, Tran, Eric, Du, Xin, Dong, Jiajun, Sudholz, Harrison, Chen, Hao, Qu, Zihan, Huntington, Nicholas D., Babon, Jeffrey J., Kershaw, Nadia J., Zhang, Zhong-Yin, Baell, Jonathan B., Wiede, Florian, Tiganis, Tony
Publicado 2023

Screening of the ‘Open Scaffolds’ collection from Compounds Australia identifies a new chemical entity with anthelmintic activities against different developmental stages of the ba...

por Preston, Sarah, Jiao, Yaqing, Baell, Jonathan B., Keiser, Jennifer, Crawford, Simon, Koehler, Anson V., Wang, Tao, Simpson, Moana M., Kaplan, Ray M., Cowley, Karla J., Simpson, Kaylene J., Hofmann, Andreas, Jabbar, Abdul, Gasser, Robin B.
Publicado 2017

Assay interference and off-target liabilities of reported histone acetyltransferase inhibitors

por Dahlin, Jayme L., Nelson, Kathryn M., Strasser, Jessica M., Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena M., Organ, Shawna, Cuellar, Matthew, Singh, Gurpreet, Shrimp, Jonathan H., Nguyen, Nghi, Meier, Jordan L., Arrowsmith, Cheryl H., Brown, Peter J., Baell, Jonathan B., Walters, Michael A.
Publicado 2017

Tetrahydroquinoxalines induce a lethal evisceration phenotype in Haemonchus contortus in vitro

por Jiao, Yaqing, Preston, Sarah, Garcia-Bustos, Jose F., Baell, Jonathan B., Ventura, Sabatino, Le, Thuy, McNamara, Nicole, Nguyen, Nghi, Botteon, Antony, Skinner, Cameron, Danne, Jill, Ellis, Sarah, Koehler, Anson V., Wang, Tao, Chang, Bill C.H., Hofmann, Andreas, Jabbar, Abdul, Gasser, Robin B.
Publicado 2018

Crystal structure of the M(5) muscarinic acetylcholine receptor

por Vuckovic, Ziva, Gentry, Patrick R., Berizzi, Alice E., Hirata, Kunio, Varghese, Swapna, Thompson, Geoff, van der Westhuizen, Emma T., Burger, Wessel A. C., Rahmani, Raphaël, Valant, Celine, Langmead, Christopher J., Lindsley, Craig W., Baell, Jonathan B., Tobin, Andrew B., Sexton, Patrick M., Christopoulos, Arthur, Thal, David M.
Publicado 2019

GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity

por Menon, Deepthi, Innes, Ashlee, Oakley, Aaron J., Dahlstrom, Jane E., Jensen, Lora M., Brüstle, Anne, Tummala, Padmaja, Rooke, Melissa, Casarotto, Marco G., Baell, Jonathan B., Nguyen, Nghi, Xie, Yiyue, Cuellar, Matthew, Strasser, Jessica, Dahlin, Jayme L., Walters, Michael A., Burgio, Gaetan, O’Neill, Luke A. J., Board, Philip G.
Publicado 2017

Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator

por Ovens, Ashley J., Gee, Yi Sing, Ling, Naomi X.Y., Yu, Dingyi, Hardee, Justin P., Chung, Jin D., Ngoei, Kevin R.W., Waters, Nicholas J., Hoffman, Nolan J., Scott, John W., Loh, Kim, Spengler, Katrin, Heller, Regine, Parker, Michael W., Lynch, Gordon S., Huang, Fei, Galic, Sandra, Kemp, Bruce E., Baell, Jonathan B., Oakhill, Jonathan S., Langendorf, Christopher G.
Publicado 2022

Reference compounds for characterizing cellular injury in high-content cellular morphology assays

por Dahlin, Jayme L., Hua, Bruce K., Zucconi, Beth E., Nelson, Shawn D., Singh, Shantanu, Carpenter, Anne E., Shrimp, Jonathan H., Lima-Fernandes, Evelyne, Wawer, Mathias J., Chung, Lawrence P. W., Agrawal, Ayushi, O’Reilly, Mary, Barsyte-Lovejoy, Dalia, Szewczyk, Magdalena, Li, Fengling, Lak, Parnian, Cuellar, Matthew, Cole, Philip A., Meier, Jordan L., Thomas, Tim, Baell, Jonathan B., Brown, Peter J., Walters, Michael A., Clemons, Paul A., Schreiber, Stuart L., Wagner, Bridget K.
Publicado 2023