Heterocycle-Based Multicomponent Reactions in Drug Discovery: From Hit Finding to Rational Design

por Nadal Rodríguez, Pau, Ghashghaei, Ouldouz, Bagán, Andrea, Escolano, Carmen, Lavilla, Rodolfo
Publicado 2022

Amelioration of BPSD-Like Phenotype and Cognitive Decline in SAMP8 Mice Model Accompanied by Molecular Changes after Treatment with I(2)-Imidazoline Receptor Ligand MCR5

por Vasilopoulou, Foteini, Bagan, Andrea, Rodriguez-Arevalo, Sergio, Escolano, Carmen, Griñán-Ferré, Christian, Pallàs, Mercè
Publicado 2020

Design and Synthesis of AMPK Activators and GDF15 Inducers

por Zhang, Meijian, Bagán, Andrea, Martínez, Donna, Barroso, Emma, Palomer, Xavier, Vázquez, Santiago, Escolano, Carmen, Vázquez-Carrera, Manuel
Publicado 2023

An Imidazoline 2 Receptor Ligand Relaxes Mouse Aorta via Off-Target Mechanisms Resistant to Aging

por Jiménez-Altayó, Francesc, Cabrera, Anna, Bagán, Andrea, Giménez-Llort, Lydia, D’Ocon, Pilar, Pérez, Belén, Pallàs, Mercè, Escolano, Carmen
Publicado 2022

Insights into the Pharmacokinetics and In Vitro Cell-Based Studies of the Imidazoline I(2) Receptor Ligand B06

por Bagán, Andrea, Morales-García, José A., Griñán-Ferré, Christian, Díaz, Caridad, Pérez del Palacio, José, Ramos, Maria C., Vicente, Francisca, Pérez, Belén, Brea, José, Loza, María Isabel, Pallàs, Mercè, Escolano, Carmen
Publicado 2022

Preclinical Evaluation of an Imidazole-Linked Heterocycle for Alzheimer’s Disease

por Bagán, Andrea, Rodriguez-Arévalo, Sergio, Taboada-Jara, Teresa, Griñán-Ferré, Christian, Pallàs, Mercè, Brocos-Mosquera, Iria, Callado, Luis F., Morales-García, José A., Pérez, Belén, Diaz, Caridad, Fernández-Godino, Rosario, Genilloud, Olga, Beljkas, Milan, Oljacic, Slavica, Nikolic, Katarina, Escolano, Carmen
Publicado 2023