An Overview of Biological and Computational Methods for Designing Mechanism-Informed Anti-biofilm Agents

por An, Andy Y., Choi, Ka-Yee Grace, Baghela, Arjun S., Hancock, Robert E. W.
Publicado 2021

Facilitating systems-level analyses of all-cause and Covid-mediated sepsis through SeptiSearch, a manually-curated compendium of dysregulated gene sets

por Baghela, Arjun S., Tam, Jasmine, Blimkie, Travis M., Dhillon, Bhavjinder K., Hancock, Robert E.W.
Publicado 2023

NtrBC Regulates Invasiveness and Virulence of Pseudomonas aeruginosa During High-Density Infection

por Alford, Morgan A., Baghela, Arjun, Yeung, Amy T. Y., Pletzer, Daniel, Hancock, Robert E. W.
Publicado 2020

Systems Biology Approaches to Understanding the Human Immune System

por Dhillon, Bhavjinder K., Smith, Maren, Baghela, Arjun, Lee, Amy H. Y., Hancock, Robert E. W.
Publicado 2020

The Stringent Stress Response Controls Proteases and Global Regulators under Optimal Growth Conditions in Pseudomonas aeruginosa

por Pletzer, Daniel, Blimkie, Travis M., Wolfmeier, Heidi, Li, Yicong, Baghela, Arjun, Lee, Amy H. Y., Falsafi, Reza, Hancock, Robert E. W.
Publicado 2020

Severe COVID-19 and non-COVID-19 severe sepsis converge transcriptionally after a week in the intensive care unit, indicating common disease mechanisms

por An, Andy Y., Baghela, Arjun, Zhang, Peter, Falsafi, Reza, Lee, Amy H., Trahtemberg, Uriel, Baker, Andrew J., dos Santos, Claudia C., Hancock, Robert E. W.
Publicado 2023

Persistence is key: unresolved immune dysfunction is lethal in both COVID-19 and non-COVID-19 sepsis

por An, Andy Y., Baghela, Arjun, Zhang, Peter, Falsafi, Reza, Lee, Amy H., Trahtemberg, Uriel, Baker, Andrew J., dos Santos, Claudia C., Hancock, Robert E. W.
Publicado 2023

Post-COVID symptoms are associated with endotypes reflecting poor inflammatory and hemostatic modulation

por An, Andy Yi, Baghela, Arjun, Zhang, Peter G. Y., Blimkie, Travis M., Gauthier, Jeff, Kaufmann, Daniel Elias, Acton, Erica, Lee, Amy H. Y., Levesque, Roger C., Hancock, Robert E. W.
Publicado 2023

Predicting severity in COVID-19 disease using sepsis blood gene expression signatures

por Baghela, Arjun, An, Andy, Zhang, Peter, Acton, Erica, Gauthier, Jeff, Brunet-Ratnasingham, Elsa, Blimkie, Travis, Freue, Gabriela Cohen, Kaufmann, Daniel, Lee, Amy H. Y., Levesque, Roger C., Hancock, Robert E. W.
Publicado 2023

Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures

por Baghela, Arjun, Pena, Olga M., Lee, Amy H., Baquir, Beverlie, Falsafi, Reza, An, Andy, Farmer, Susan W., Hurlburt, Andrew, Mondragon-Cardona, Alvaro, Rivera, Juan Diego, Baker, Andrew, Trahtemberg, Uriel, Shojaei, Maryam, Jimenez-Canizales, Carlos Eduardo, dos Santos, Claudia C., Tang, Benjamin, Bouma, Hjalmar R., Cohen Freue, Gabriela V., Hancock, Robert E.W.
Publicado 2022