Design of a pan-betacoronavirus vaccine candidate through a phylogenetically informed approach

por Lewitus, Eric, Bai, Hongjun, Rolland, Morgane
Publicado 2023

Finding multiple target optimal intervention in disease-related molecular network

por Yang, Kun, Bai, Hongjun, Ouyang, Qi, Lai, Luhua, Tang, Chao
Publicado 2008

Optimal sequence-based design for multi-antigen HIV-1 vaccines using minimally distant antigens

por Lewitus, Eric, Hoang, Jennifer, Li, Yifan, Bai, Hongjun, Rolland, Morgane
Publicado 2022

The breadth of HIV-1 neutralizing antibodies depends on the conservation of key sites in their epitopes

por Bai, Hongjun, Li, Yifan, Michael, Nelson L., Robb, Merlin L., Rolland, Morgane
Publicado 2019

A SARS-CoV-2 vaccine candidate would likely match all currently circulating variants

por Dearlove, Bethany, Lewitus, Eric, Bai, Hongjun, Li, Yifan, Reeves, Daniel B., Joyce, M. Gordon, Scott, Paul T., Amare, Mihret F., Vasan, Sandhya, Michael, Nelson L., Modjarrad, Kayvon, Rolland, Morgane
Publicado 2020

A Cryptic Site of Vulnerability on the Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein

por Joyce, M. Gordon, Sankhala, Rajeshwer S., Chen, Wei-Hung, Choe, Misook, Bai, Hongjun, Hajduczki, Agnes, Yan, Lianying, Sterling, Spencer L., Peterson, Caroline E., Green, Ethan C., Smith, Clayton, de Val, Natalia, Amare, Mihret, Scott, Paul, Laing, Eric D., Broder, Christopher C., Rolland, Morgane, Michael, Nelson L., Modjarrad, Kayvon
Publicado 2020

Limited Evidence for a Relationship between HIV-1 Glycan Shield Features in Early Infection and the Development of Neutralization Breadth

por Li, Yifan, Bai, Hongjun, Sanders-Buell, Eric, Dussupt, Vincent, Townsley, Samantha, Donofrio, Gina, Bose, Meera, O’Sullivan, Anne Marie, Kibuuka, Hannah, Maganga, Lucas, Nitayaphan, Sorachai, Kosgei, Josphat, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Eller, Leigh Anne, Michael, Nelson L., Robb, Merlin L., Ake, Julie, Vasan, Sandhya, Tovanabutra, Sodsai, Krebs, Shelly J., Rolland, Morgane
Publicado 2021

HIV-1 infections with multiple founders associate with the development of neutralization breadth

por Lewitus, Eric, Townsley, Samantha M., Li, Yifan, Donofrio, Gina C., Dearlove, Bethany L., Bai, Hongjun, Sanders-Buell, Eric, O’Sullivan, Anne Marie, Bose, Meera, Kibuuka, Hannah, Maganga, Lucas, Nitayaphan, Sorachai, Sawe, Fredrick K., Eller, Leigh Anne, Michael, Nelson L., Polonis, Victoria R., Ake, Julie A., Vasan, Sandhya, Robb, Merlin L., Tovanabutra, Sodsai, Krebs, Shelly J., Rolland, Morgane
Publicado 2022

Long-term antiretroviral therapy initiated in acute HIV infection prevents residual dysfunction of HIV-specific CD8(+) T cells

por Takata, Hiroshi, Kakazu, Juyeon C., Mitchell, Julie L., Kroon, Eugene, Colby, Donn J., Sacdalan, Carlo, Bai, Hongjun, Ehrenberg, Philip K., Geretz, Aviva, Buranapraditkun, Supranee, Pinyakorn, Suteeraporn, Intasan, Jintana, Tipsuk, Somporn, Suttichom, Duanghathai, Prueksakaew, Peeriya, Chalermchai, Thep, Chomchey, Nitiya, Phanuphak, Nittaya, de Souza, Mark, Michael, Nelson L., Robb, Merlin L., Haddad, Elias K., Crowell, Trevor A, Vasan, Sandhya, Valcour, Victor G., Douek, Daniel C., Thomas, Rasmi, Rolland, Morgane, Chomont, Nicolas, Ananworanich, Jintanat, Trautmann, Lydie
Publicado 2022

Targeting the Spike Receptor Binding Domain Class V Cryptic Epitope by an Antibody with Pan-Sarbecovirus Activity

por Jensen, Jaime L., Sankhala, Rajeshwer S., Dussupt, Vincent, Bai, Hongjun, Hajduczki, Agnes, Lal, Kerri G., Chang, William C., Martinez, Elizabeth J., Peterson, Caroline E., Golub, Emily S., Rees, Phyllis A., Mendez-Rivera, Letzibeth, Zemil, Michelle, Kavusak, Erin, Mayer, Sandra V., Wieczorek, Lindsay, Kannan, Shruthi, Doranz, Benjamin J., Davidson, Edgar, Yang, Eun Sung, Zhang, Yi, Chen, Man, Choe, Misook, Wang, Lingshu, Gromowski, Gregory D., Koup, Richard A., Michael, Nelson L., Polonis, Victoria R., Rolland, Morgane, Modjarrad, Kayvon, Krebs, Shelly J., Joyce, M. Gordon
Publicado 2023

Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound

por Cale, Evan M., Bai, Hongjun, Bose, Meera, Messina, Michael A., Colby, Donn J., Sanders-Buell, Eric, Dearlove, Bethany, Li, Yifan, Engeman, Emily, Silas, Daniel, O’Sullivan, Anne Marie, Mann, Brendan, Pinyakorn, Suteeraporn, Intasan, Jintana, Benjapornpong, Khunthalee, Sacdalan, Carlo, Kroon, Eugène, Phanuphak, Nittaya, Gramzinski, Robert, Vasan, Sandhya, Robb, Merlin L., Michael, Nelson L., Lynch, Rebecca M., Bailer, Robert T., Pagliuzza, Amélie, Chomont, Nicolas, Pegu, Amarendra, Doria-Rose, Nicole A., Trautmann, Lydie, Crowell, Trevor A., Mascola, John R., Ananworanich, Jintanat, Tovanabutra, Sodsai, Rolland, Morgane
Publicado 2020

Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features

por Magaret, Craig, Li, Li, deCamp, Allan, Rolland, Morgane, Juraska, Michal, Williamson, Brian, Ludwig, James, Molitor, Cindy, Benkeser, David, Luedtke, Alex, Simpkins, Brian, Carpp, Lindsay, Bai, Hongjun, Deariove, Bethany, Greninger, Alexander, Roychoudhury, Pavitra, Sadoff, Jerald, Gray, Glenda, Roels, Sanne, Vandebosch, An, Stieh, Daniel, Le Gars, Mathieu, Vingerhoets, Johan, Grinsztejn, Beatriz, Goepfert, Paul, Truyers, Carla, Van Dromme, Ilse, Swann, Edith, Marovich, Mary, Follmann, Dean, Neuzil, Kathleen, Corey, Lawrence, Hyrien, Ollivier, Paiva de Sousa, Leonardo, Casapia, Martin, Losso, Marcelo, Little, Susan, Gaur, Aditya, Bekker, Linda-Gail, Garrett, Nigel, Heng, Fei, Sun, Yanqing, Gilbert, Peter
Publicado 2023

RV144 vaccine imprinting constrained HIV-1 evolution following breakthrough infection

por Lewitus, Eric, Sanders-Buell, Eric, Bose, Meera, O’Sullivan, Anne Marie, Poltavee, Kultida, Li, Yifan, Bai, Hongjun, Mdluli, Thembi, Donofrio, Gina, Slike, Bonnie, Zhao, Hong, Wong, Kim, Chen, Lennie, Miller, Shana, Lee, Jenica, Ahani, Bahar, Lepore, Steven, Muhammad, Sevan, Grande, Rebecca, Tran, Ursula, Dussupt, Vincent, Mendez-Rivera, Letzibeth, Nitayaphan, Sorachai, Kaewkungwal, Jaranit, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, O’Connell, Robert J, Janes, Holly, Gilbert, Peter B, Gramzinski, Robert, Vasan, Sandhya, Robb, Merlin L, Michael, Nelson L, Krebs, Shelly J, Herbeck, Joshua T, Edlefsen, Paul T, Mullins, James I, Kim, Jerome H, Tovanabutra, Sodsai, Rolland, Morgane
Publicado 2021

Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity

por Chen, Wei-Hung, Hajduczki, Agnes, Martinez, Elizabeth J., Bai, Hongjun, Matz, Hanover, Hill, Thomas M., Lewitus, Eric, Chang, William C., Dawit, Layla, Peterson, Caroline E., Rees, Phyllis A., Ajayi, Adelola B., Golub, Emily S., Swafford, Isabella, Dussupt, Vincent, David, Sapna, Mayer, Sandra V., Soman, Sandrine, Kuklis, Caitlin, Corbitt, Courtney, King, Jocelyn, Choe, Misook, Sankhala, Rajeshwer S., Thomas, Paul V., Zemil, Michelle, Wieczorek, Lindsay, Hart, Tricia, Duso, Debora, Kummer, Larry, Yan, Lianying, Sterling, Spencer L., Laing, Eric D., Broder, Christopher C., Williams, Jazmean K., Davidson, Edgar, Doranz, Benjamin J., Krebs, Shelly J., Polonis, Victoria R., Paquin-Proulx, Dominic, Rolland, Morgane, Reiley, William W., Gromowski, Gregory D., Modjarrad, Kayvon, Dooley, Helen, Joyce, M. Gordon
Publicado 2023

Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the CD4 binding site of Env-gp120

por deCamp, Allan C., Rolland, Morgane, Edlefsen, Paul T., Sanders-Buell, Eric, Hall, Breana, Magaret, Craig A., Fiore-Gartland, Andrew J., Juraska, Michal, Carpp, Lindsay N., Karuna, Shelly T., Bose, Meera, LePore, Steven, Miller, Shana, O'Sullivan, Annemarie, Poltavee, Kultida, Bai, Hongjun, Dommaraju, Kalpana, Zhao, Hong, Wong, Kim, Chen, Lennie, Ahmed, Hasan, Goodman, Derrick, Tay, Matthew Z., Gottardo, Raphael, Koup, Richard A., Bailer, Robert, Mascola, John R., Graham, Barney S., Roederer, Mario, O’Connell, Robert J., Michael, Nelson L., Robb, Merlin L., Adams, Elizabeth, D’Souza, Patricia, Kublin, James, Corey, Lawrence, Geraghty, Daniel E., Frahm, Nicole, Tomaras, Georgia D., McElrath, M. Juliana, Frenkel, Lisa, Styrchak, Sheila, Tovanabutra, Sodsai, Sobieszczyk, Magdalena E., Hammer, Scott M., Kim, Jerome H., Mullins, James I., Gilbert, Peter B.
Publicado 2017

Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor

por Dussupt, Vincent, Sankhala, Rajeshwer S., Gromowski, Gregory D., Donofrio, Gina, De La Barrera, Rafael A., Larocca, Rafael A., Zaky, Weam, Mendez-Rivera, Letzibeth, Choe, Misook, Davidson, Edgar, McCracken, Michael K., Brien, James D., Abbink, Peter, Bai, Hongjun, Bryan, Aubrey L., Bias, Candace Hope, Berry, Irina Maljkovic, Botero, Nubia, Cook, Tanya, Doria-Rose, Nicole A., Escuer, Ariadna Grinyo i, Frimpong, Justice Akuoku, Geretz, Aviva, Hernandez, Mayda, Hollidge, Bradley S., Jian, Ningbo, Kabra, Kareem, Leggat, David J., Liu, Jinyan, Pinto, Amelia K., Rutvisuttinunt, Wiriya, Setliff, Ian, Tran, Ursula, Townsley, Samantha, Doranz, Benjamin J., Rolland, Morgane, McDermott, Adrian B., Georgiev, Ivelin S., Thomas, Rasmi, Robb, Merlin L., Eckels, Kenneth H., Barranco, Elizabeth, Koren, Michael, Smith, Darci R., Jarman, Richard G., George, Sarah L., Stephenson, Kathryn E., Barouch, Dan H., Modjarrad, Kayvon, Michael, Nelson L., Joyce, M. Gordon, Krebs, Shelly J.
Publicado 2020