Generation of a Novel High-Affinity Antibody Binding to PCSK9 Catalytic Domain with Slow Dissociation Rate by CDR-Grafting, Alanine Scanning and Saturated Site-Directed Mutagenesis...

por Bai, Zhengli, Xu, Menglong, Mei, Ying, Hu, Tuo, Zhang, Panpan, Chen, Manman, Lv, Wenxiu, Lu, Chenchen, Tan, Shuhua
Publicado 2021

A Novel Fully Human Agonistic Single Chain Fragment Variable Antibody Targeting Death Receptor 5 with Potent Antitumor Activity In Vitro and In Vivo

por Lei, Gaoxin, Xu, Menglong, Xu, Zhipan, Gu, Lili, Lu, Chenchen, Bai, Zhengli, Wang, Yue, Zhang, Yongbo, Hu, Huajing, Jiang, Yiwei, Zhao, Wenfeng, Tan, Shuhua
Publicado 2017

Development of a novel, fully human, anti-PCSK9 antibody with potent hypolipidemic activity by utilizing phage display-based strategy

por Xu, Menglong, Lei, Gaoxin, Chen, Manman, Wang, Ke, Lv, Wenxiu, Zhang, Panpan, Hu, Tuo, Gao, Jie, Lu, Chenchen, Mei, Ying, Xu, Zhipan, Bai, Zhengli, Hu, Huajing, Jiang, Yiwei, Tan, Shuhua
Publicado 2021