Gene therapy for neovascular age-related macular degeneration: rationale, clinical trials and future directions

por de Guimaraes, Thales Antonio Cabral, Georgiou, Michalis, Bainbridge, James W B, Michaelides, Michel
Publicado 2021

Severe Loss of Tritan Color Discrimination in RPE65 Associated Leber Congenital Amaurosis

por Kumaran, Neruban, Ripamonti, Caterina, Kalitzeos, Angelos, Rubin, Gary S., Bainbridge, James W. B., Michaelides, Michel
Publicado 2018

Validation of a Vision-Guided Mobility Assessment for RPE65-Associated Retinal Dystrophy

por Kumaran, Neruban, Ali, Robin R., Tyler, Nick A., Bainbridge, James W. B., Michaelides, Michel, Rubin, Gary S.
Publicado 2020

A Cross-Sectional and Longitudinal Study of Retinal Sensitivity in RPE65-Associated Leber Congenital Amaurosis

por Kumaran, Neruban, Rubin, Gary S., Kalitzeos, Angelos, Fujinami, Kaoru, Bainbridge, James W. B., Weleber, Richard G., Michaelides, Michel
Publicado 2018

Assessment and In Vivo Scoring of Murine Experimental Autoimmune Uveoretinitis Using Optical Coherence Tomography

por Chu, Colin J., Herrmann, Philipp, Carvalho, Livia S., Liyanage, Sidath E., Bainbridge, James W. B., Ali, Robin R., Dick, Andrew D., Luhmann, Ulrich F. O.
Publicado 2013

Accelerated oxygen-induced retinopathy is a reliable model of ischemia-induced retinal neovascularization

por Villacampa, Pilar, Menger, Katja E., Abelleira, Laura, Ribeiro, Joana, Duran, Yanai, Smith, Alexander J., Ali, Robin R., Luhmann, Ulrich F., Bainbridge, James W. B.
Publicado 2017

Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration

por Luhmann, Ulrich F.O., Carvalho, Livia S., Robbie, Scott J., Cowing, Jill A., Duran, Yanai, Munro, Peter M.G., Bainbridge, James W.B., Ali, Robin R.
Publicado 2013

Isolation of Human Photoreceptor Precursors via a Cell Surface Marker Panel from Stem Cell‐Derived Retinal Organoids and Fetal Retinae

por Lakowski, Jörn, Welby, Emily, Budinger, Dimitri, Di Marco, Fabiana, Di Foggia, Valentina, Bainbridge, James W.B., Wallace, Kyle, Gamm, David M., Ali, Robin R., Sowden, Jane C.
Publicado 2018

Facedown Positioning Following Surgery for Large Full-Thickness Macular Hole: A Multicenter Randomized Clinical Trial

por Pasu, Saruban, Bell, Lauren, Zenasni, Zohra, Lanz, Doris, Simmonds, Irene A, Thompson, Ann, Yorston, David, Laidlaw, D. Alistair H., Bunce, Catey, Hooper, Richard, Bainbridge, James W. B.
Publicado 2020

Retinal Structure in RPE65-Associated Retinal Dystrophy

por Kumaran, Neruban, Georgiou, Michalis, Bainbridge, James W. B., Bertelsen, Mette, Larsen, Michael, Blanco-Kelly, Fiona, Ayuso, Carmen, Tran, Hoai Viet, Munier, Francis L., Kalitzeos, Angelos, Michaelides, Michel
Publicado 2020

HIF-1alpha and HIF-2alpha Are Differentially Activated in Distinct Cell Populations in Retinal Ischaemia

por Mowat, Freya M., Luhmann, Ulrich F. O., Smith, Alexander J., Lange, Clemens, Duran, Yanai, Harten, Sarah, Shukla, Deepa, Maxwell, Patrick H., Ali, Robin R., Bainbridge, James W. B.
Publicado 2010

The Tight Junction Associated Signalling Proteins ZO-1 and ZONAB Regulate Retinal Pigment Epithelium Homeostasis in Mice

por Georgiadis, Anastasios, Tschernutter, Marion, Bainbridge, James W. B., Balaggan, Kamaljit S., Mowat, Freya, West, Emma L., Munro, Peter M. G., Thrasher, Adrian J., Matter, Karl, Balda, Maria S., Ali, Robin R.
Publicado 2010

Intravitreal Pharmacokinetic Study of the Antiangiogenic Glycoprotein Opticin

por del Amo, Eva M., Griffiths, John R., Klaska, Izabela P., Hoke, Justin, White, Anne, Aarons, Leon, Cooper, Garth J. S., Bainbridge, James W. B., Bishop, Paul N., Unwin, Richard D.
Publicado 2020

Subretinal delivery of adeno-associated virus serotype 2 results in minimal immune responses that allow repeat vector administration in immunocompetent mice

por Barker, Susie E, Broderick, Cathryn A, Robbie, Scott J, Duran, Yanai, Natkunarajah, Mythili, Buch, Prateek, Balaggan, Kamaljit S, MacLaren, Robert E, Bainbridge, James W B, Smith, Alexander J, Ali, Robin R
Publicado 2009

Transplantation of Photoreceptor Precursors Isolated via a Cell Surface Biomarker Panel From Embryonic Stem Cell‐Derived Self‐Forming Retina

por Lakowski, Jorn, Gonzalez‐Cordero, Anai, West, Emma L., Han, Ya‐Ting, Welby, Emily, Naeem, Arifa, Blackford, Samuel J. I., Bainbridge, James W. B., Pearson, Rachael A., Ali, Robin R., Sowden, Jane C.
Publicado 2015

Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179

por Nishiguchi, Koji M., Carvalho, Livia S., Rizzi, Matteo, Powell, Kate, Holthaus, Sophia-Martha kleine, Azam, Selina A., Duran, Yanai, Ribeiro, Joana, Luhmann, Ulrich F. O., Bainbridge, James W. B., Smith, Alexander J., Ali, Robin R.
Publicado 2015

Spatiotemporal control of actomyosin contractility by MRCKβ signaling drives phagocytosis

por Zihni, Ceniz, Georgiadis, Anastasios, Ramsden, Conor M., Sanchez-Heras, Elena, Haas, Alexis J., Nommiste, Britta, Semenyuk, Olha, Bainbridge, James W.B., Coffey, Peter J., Smith, Alexander J., Ali, Robin R., Balda, Maria S., Matter, Karl
Publicado 2022

The severity of retinal pathology in homozygous Crb1(rd8/rd8) mice is dependent on additional genetic factors

por Luhmann, Ulrich F.O., Carvalho, Livia S., Holthaus, Sophia-Martha kleine, Cowing, Jill A., Greenaway, Simon, Chu, Colin J., Herrmann, Philipp, Smith, Alexander J., Munro, Peter M.G., Potter, Paul, Bainbridge, James W.B., Ali, Robin R.
Publicado 2015

A simple method for in vivo labelling of infiltrating leukocytes in the mouse retina using indocyanine green dye

por Sim, Dawn A., Chu, Colin J., Selvam, Senthil, Powner, Michael B., Liyanage, Sidath, Copland, David A., Keane, Pearse A., Tufail, Adnan, Egan, Catherine A., Bainbridge, James W. B., Lee, Richard W., Dick, Andrew D., Fruttiger, Marcus
Publicado 2015

Stabilization of myeloid-derived HIFs promotes vascular regeneration in retinal ischemia

por Villacampa, Pilar, Liyanage, Sidath E., Klaska, Izabela P., Cristante, Enrico, Menger, Katja E., Sampson, Robert D., Barlow, Maeve, Abelleira-Hervas, Laura, Duran, Yanai, Smith, Alexander J., Ali, Robin R., Luhmann, Ulrich F. O., Bainbridge, James W. B.
Publicado 2019