Acute inhibition of the CNS-specific kinase TTBK1 significantly lowers tau phosphorylation at several disease relevant sites

por Dillon, Gregory M., Henderson, Jaclyn L., Bao, Channa, Joyce, John A., Calhoun, Michael, Amaral, Brenda, King, Kristopher W., Bajrami, Bekim, Rabah, Dania
Publicado 2020

Phosphorylated Dihydroceramides from Common Human Bacteria Are Recovered in Human Tissues

por Nichols, Frank C., Yao, Xudong, Bajrami, Bekim, Downes, Julia, Finegold, Sydney M., Knee, Erica, Gallagher, James J., Housley, William J., Clark, Robert B.
Publicado 2011

Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain

por Burns, Jeremy Carlos, Cotleur, Bunny, Walther, Dirk M, Bajrami, Bekim, Rubino, Stephen J, Wei, Ru, Franchimont, Nathalie, Cotman, Susan L, Ransohoff, Richard M, Mingueneau, Michael
Publicado 2020

Antisense Oligonucleotide-Mediated Reduction of HDAC6 Does Not Reduce Tau Pathology in P301S Tau Transgenic Mice

por Valencia, Antonio, Bieber, Veronica L. Reinhart, Bajrami, Bekim, Marsh, Galina, Hamann, Stefan, Wei, Ru, Ling, Karen, Rigo, Frank, Arnold, H. Moore, Golonzhka, Olga, Hering, Heike
Publicado 2021

Targeted Proteomic Quantitation of the Absolute Expression and Turnover of Cystic Fibrosis Transmembrane Conductance Regulator in the Apical Plasma Membrane

por McShane, Adam J., Bajrami, Bekim, Ramos, Alex A., Diego-Limpin, Pamela A., Farrokhi, Vahid, Coutermarsh, Bonita A., Stanton, Bruce A., Jensen, Tim, Riordan, John R., Wetmore, Diana, Joseloff, Elizabeth, Yao, Xudong
Publicado 2014

Elucidation of the GSK3α Structure Informs the Design of Novel, Paralog-Selective Inhibitors

por Amaral, Brenda, Capacci, Andrew, Anderson, Trip, Tezer, Ceren, Bajrami, Bekim, Lulla, Mukesh, Lucas, Brian, Chodaparambil, Jayanth V., Marcotte, Douglas, Kumar, P. Rajesh, Murugan, Paramasivam, Spilker, Kerri, Cullivan, Mike, Wang, Ti, Peterson, Anton C., Enyedy, Istvan, Ma, Bin, Chen, TeYu, Yousaf, Zain, Calhoun, Michael, Golonzhka, Olga, Dillon, Gregory M., Koirala, Samir
Publicado 2023

Next‐generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells...

por Bame, Eris, Tang, Hao, Burns, Jeremy C, Arefayene, Million, Michelsen, Klaus, Ma, Bin, Marx, Isaac, Prince, Robin, Roach, Allie M, Poreci, Urjana, Donaldson, Douglas, Cullen, Patrick, Casey, Fergal, Zhu, Jing, Carlile, Thomas M, Sangurdekar, Dipen, Zhang, Baohong, Trapa, Patrick, Santoro, Joseph, Muragan, Param, Pellerin, Alex, Rubino, Stephen, Gianni, Davide, Bajrami, Bekim, Peng, Xiaomei, Coppell, Alex, Riester, Katherine, Belachew, Shibeshih, Mehta, Devangi, Palte, Mike, Hopkins, Brian T, Scaramozza, Matthew, Franchimont, Nathalie, Mingueneau, Michael
Publicado 2021