Using Global Analysis to Extend the Accuracy and Precision of Binding Measurements with T cell Receptors and Their Peptide/MHC Ligands

por Blevins, Sydney J., Baker, Brian M.
Publicado 2017

Conformational changes and flexibility in T-cell receptor recognition of peptide–MHC complexes

por Armstrong, Kathryn M., Piepenbrink, Kurt H., Baker, Brian M.
Publicado 2008

Peptide and Peptide-Dependent Motions in MHC Proteins: Immunological Implications and Biophysical Underpinnings

por Ayres, Cory M., Corcelli, Steven A., Baker, Brian M.
Publicado 2017

Physicochemical Heuristics for Identifying High Fidelity, Near-Native Structural Models of Peptide/MHC Complexes

por Keller, Grant L. J., Weiss, Laura I., Baker, Brian M.
Publicado 2022

2064: Deconstructing the peptide specificity of TCR recognition

por Riley, Timothy P., Mendoza, Juan, Garcia, K. C., Baker, Brian M.
Publicado 2018

The basis for limited specificity and MHC restriction in a T cell receptor interface

por Piepenbrink, Kurt H., Blevins, Sydney J., Scott, Daniel R., Baker, Brian M.
Publicado 2013

Differential utilization of binding loop flexibility in T cell receptor ligand selection and cross-reactivity

por Ayres, Cory M., Scott, Daniel R., Corcelli, Steven A., Baker, Brian M.
Publicado 2016

Advanced Genomics-Based Approaches for Defining Allograft Rejection With Single Cell Resolution

por Shi, Tiffany, Roskin, Krishna, Baker, Brian M., Woodle, E. Steve, Hildeman, David
Publicado 2021

Dynamic allostery controls the peptide sensitivity of the Ly49C natural killer receptor

por Ma, Jiaqi, Ayres, Cory M., Hellman, Lance M., Devlin, Jason R., Baker, Brian M.
Publicado 2021

Identification of a Crucial Energetic Footprint on the α1 Helix of Human Histocompatibility Leukocyte Antigen (Hla)-A2 That Provides Functional Interactions for Recognition by Tax...

por Baker, Brian M., Turner, Richard V., Gagnon, Susan J., Wiley, Don C., Biddison, William E.
Publicado 2001

Changing the peptide specificity of a human T cell receptor by directed evolution

por Smith, Sheena N., Wang, Yuhang, Baylon, Javier L., Singh, Nishant K., Baker, Brian M., Tajkhorshid, Emad, Kranz, David M.
Publicado 2014

Computational Design of the Affinity and Specificity of a Therapeutic T Cell Receptor

por Pierce, Brian G., Hellman, Lance M., Hossain, Moushumi, Singh, Nishant K., Vander Kooi, Craig W., Weng, Zhiping, Baker, Brian M.
Publicado 2014

Dynamically Driven Allostery in MHC Proteins: Peptide-Dependent Tuning of Class I MHC Global Flexibility

por Ayres, Cory M., Abualrous, Esam T., Bailey, Alistair, Abraham, Christian, Hellman, Lance M., Corcelli, Steven A., Noé, Frank, Elliott, Tim, Baker, Brian M.
Publicado 2019

Structure Based Prediction of Neoantigen Immunogenicity

por Riley, Timothy P., Keller, Grant L. J., Smith, Angela R., Davancaze, Lauren M., Arbuiso, Alyssa G., Devlin, Jason R., Baker, Brian M.
Publicado 2019

Structural interplay between germline and adaptive recognition determines TCR-peptide-MHC cross-reactivity

por Adams, Jarrett J., Narayanan, Samanthi, Birnbaum, Michael E., Sidhu, Sachdev S., Blevins, Sydney J., Gee, Marvin H., Sibener, Leah V., Baker, Brian M., Kranz, David M., Garcia, K. Christopher
Publicado 2015

Increased Peptide Contacts Govern High Affinity Binding of a Modified TCR Whilst Maintaining a Native pMHC Docking Mode

por Cole, David K., Sami, Malkit, Scott, Daniel R., Rizkallah, Pierre J., Borbulevych, Oleg Y., Todorov, Penio T., Moysey, Ruth K., Jakobsen, Bent K., Boulter, Jonathan M., Baker, Brian M., Yi Li
Publicado 2013

T cell receptor cross-reactivity expanded by dramatic peptide/MHC adaptability

por Riley, Timothy P., Hellman, Lance M., Gee, Marvin H., Mendoza, Juan L., Alonso, Jesus A., Foley, Kendra C., Nishimura, Michael. I., Vander Kooi, Craig W., Garcia, K. Christopher, Baker, Brian M.
Publicado 2018

Mass spectrometry–driven exploration reveals nuances of neoepitope-driven tumor rejection

por Ebrahimi-Nik, Hakimeh, Michaux, Justine, Corwin, William L., Keller, Grant L.J., Shcheglova, Tatiana, Pak, HuiSong, Coukos, George, Baker, Brian M., Mandoiu, Ion I., Bassani-Sternberg, Michal, Srivastava, Pramod K.
Publicado 2019

Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity

por Duan, Fei, Duitama, Jorge, Al Seesi, Sahar, Ayres, Cory M., Corcelli, Steven A., Pawashe, Arpita P., Blanchard, Tatiana, McMahon, David, Sidney, John, Sette, Alessandro, Baker, Brian M., Mandoiu, Ion I., Srivastava, Pramod K.
Publicado 2014

An unbiased approach to defining bona fide cancer neoepitopes that elicit immune-mediated cancer rejection

por Brennick, Cory A., George, Mariam M., Moussa, Marmar M., Hagymasi, Adam T., Seesi, Sahar Al, Shcheglova, Tatiana V., Englander, Ryan P., Keller, Grant L.J., Balsbaugh, Jeremy L., Baker, Brian M., Schietinger, Andrea, Mandoiu, Ion I., Srivastava, Pramod K.
Publicado 2021