PRDM9 binding organizes hotspot nucleosomes and limits Holliday junction migration

por Baker, Christopher L., Walker, Michael, Kajita, Shimpei, Petkov, Petko M., Paigen, Kenneth
Publicado 2014

DNA binding specificities of the long zinc-finger recombination protein PRDM9

por Billings, Timothy, Parvanov, Emil D, Baker, Christopher L, Walker, Michael, Paigen, Kenneth, Petkov, Petko M
Publicado 2013

The Meiotic Recombination Activator PRDM9 Trimethylates Both H3K36 and H3K4 at Recombination Hotspots In Vivo

por Powers, Natalie R., Parvanov, Emil D., Baker, Christopher L., Walker, Michael, Petkov, Petko M., Paigen, Kenneth
Publicado 2016

PRD-2 directly regulates casein kinase I and counteracts nonsense-mediated decay in the Neurospora circadian clock

por Kelliher, Christina M, Lambreghts, Randy, Xiang, Qijun, Baker, Christopher L, Loros, Jennifer J, Dunlap, Jay C
Publicado 2020

Multimer Formation Explains Allelic Suppression of PRDM9 Recombination Hotspots

por Baker, Christopher L., Petkova, Pavlina, Walker, Michael, Flachs, Petr, Mihola, Ondrej, Trachtulec, Zdenek, Petkov, Petko M., Paigen, Kenneth
Publicado 2015

HELLS and PRDM9 form a pioneer complex to open chromatin at meiotic recombination hot spots

por Spruce, Catrina, Dlamini, Sibongakonke, Ananda, Guruprasad, Bronkema, Naomi, Tian, Hui, Paigen, Kenneth, Carter, Gregory W., Baker, Christopher L.
Publicado 2020

PRDM9 Drives Evolutionary Erosion of Hotspots in Mus musculus through Haplotype-Specific Initiation of Meiotic Recombination

por Baker, Christopher L., Kajita, Shimpei, Walker, Michael, Saxl, Ruth L., Raghupathy, Narayanan, Choi, Kwangbom, Petkov, Petko M., Paigen, Kenneth
Publicado 2015

GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance

por Taher, Jennifer, Baker, Christopher L., Cuizon, Carmelle, Masoudpour, Hassan, Zhang, Rianna, Farr, Sarah, Naples, Mark, Bourdon, Celine, Pausova, Zdenka, Adeli, Khosrow
Publicado 2014

Enhlink infers distal and context-specific enhancer-promoter linkages

por Poirion, Olivier B., Zuo, Wulin, Spruce, Catrina, Daigle, Sandra L., Olson, Ashley, Skelly, Daniel A., Chesler, Elissa J., Baker, Christopher L., White, Brian S.
Publicado 2023

Histone methyltransferase PRDM9 is not essential for meiosis in male mice

por Mihola, Ondrej, Pratto, Florencia, Brick, Kevin, Linhartova, Eliska, Kobets, Tatyana, Flachs, Petr, Baker, Christopher L., Sedlacek, Radislav, Paigen, Kenneth, Petkov, Petko M., Camerini-Otero, R. Daniel, Trachtulec, Zdenek
Publicado 2019

Affinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage

por Walker, Michael, Billings, Timothy, Baker, Christopher L., Powers, Natalie, Tian, Hui, Saxl, Ruth L., Choi, Kwangbom, Hibbs, Matthew A., Carter, Gregory W., Handel, Mary Ann, Paigen, Kenneth, Petkov, Petko M.
Publicado 2015

LCL161 enhances expansion and survival of engineered anti-tumor T cells but is restricted by death signaling

por Afsahi, Arya, Silvestri, Christopher M., Moore, Allyson E., Graham, Carly F., Bacchiochi, Kaylyn, St-Jean, Martine, Baker, Christopher L., Korneluk, Robert G., Beug, Shawn T., LaCasse, Eric C., Bramson, Jonathan L.
Publicado 2023

Naive Pluripotent Stem Cells Exhibit Phenotypic Variability that Is Driven by Genetic Variation

por Ortmann, Daniel, Brown, Stephanie, Czechanski, Anne, Aydin, Selcan, Muraro, Daniele, Huang, Yuanhua, Tomaz, Rute A., Osnato, Anna, Canu, Giovanni, Wesley, Brandon T., Skelly, Daniel A., Stegle, Oliver, Choi, Ted, Churchill, Gary A., Baker, Christopher L., Rugg-Gunn, Peter J., Munger, Steven C., Reinholdt, Laura G., Vallier, Ludovic
Publicado 2020

Variation in histone configurations correlates with gene expression across nine inbred strains of mice

por Tyler, Anna L., Spruce, Catrina, Kursawe, Romy, Haber, Annat, Ball, Robyn L., Pitman, Wendy A., Fine, Alexander D., Raghupathy, Narayanan, Walker, Michael, Philip, Vivek M., Baker, Christopher L., Mahoney, J. Matthew, Churchill, Gary A., Trowbridge, Jennifer J., Stitzel, Michael L., Paigen, Kenneth, Petkov, Petko M., Carter, Gregory W.
Publicado 2023

Unique properties of a subset of human pluripotent stem cells with high capacity for self-renewal

por Lau, Kevin X., Mason, Elizabeth A., Kie, Joshua, De Souza, David P., Kloehn, Joachim, Tull, Dedreia, McConville, Malcolm J., Keniry, Andrew, Beck, Tamara, Blewitt, Marnie E., Ritchie, Matthew E., Naik, Shalin H., Zalcenstein, Daniela, Korn, Othmar, Su, Shian, Romero, Irene Gallego, Spruce, Catrina, Baker, Christopher L., McGarr, Tracy C., Wells, Christine A., Pera, Martin F.
Publicado 2020