Pore loops of the AAA+ ClpX machine grip substrates to drive translocation and unfolding

por Martin, Andreas, Baker, Tania A., Sauer, Robert T.
Publicado 2008

Interactions between a subset of substrate side chains and AAA+ motor pore loops determine grip during protein unfolding

por Bell, Tristan A, Baker, Tania A, Sauer, Robert T
Publicado 2019

Modular and coordinated activity of AAA+ active sites in the double-ring ClpA unfoldase of the ClpAP protease

por Zuromski, Kristin L., Sauer, Robert T., Baker, Tania A.
Publicado 2020

FtsH degrades dihydrofolate reductase by recognizing a partially folded species

por Morehouse, Juhee P., Baker, Tania A., Sauer, Robert T.
Publicado 2022

AAA+ protease-adaptor structures reveal altered conformations and ring specialization

por Kim, Sora, Fei, Xue, Sauer, Robert T., Baker, Tania A.
Publicado 2022

Coordinated gripping of substrate by subunits of a AAA+ proteolytic machine

por Iosefson, Ohad, Nager, Andrew R., Baker, Tania A., Sauer, Robert T.
Publicado 2015

Division of labor between the pore-1 loops of the D1 and D2 AAA+ rings coordinates substrate selectivity of the ClpAP protease

por Zuromski, Kristin L., Kim, Sora, Sauer, Robert T., Baker, Tania A.
Publicado 2021

Dynamic and static components power unfolding in topologically closed rings of a AAA+ proteolytic machine

por Glynn, Steven E., Nager, Andrew R., Baker, Tania A., Sauer, Robert T.
Publicado 2012

Segregation of molecules at cell division reveals native protein localization

por Landgraf, Dirk, Okumus, Burak, Chien, Peter, Baker, Tania A., Paulsson, Johan
Publicado 2012

FtsH degrades kinetically stable dimers of cyclopropane fatty acid synthase via an internal degron

por Hari, Sanjay B., Morehouse, Juhee P., Baker, Tania A., Sauer, Robert T.
Publicado 2022

Mitochondrial ClpX activates an essential biosynthetic enzyme through partial unfolding

por Kardon, Julia R, Moroco, Jamie A, Engen, John R, Baker, Tania A
Publicado 2020

Regulation of Antimycin Biosynthesis Is Controlled by the ClpXP Protease

por Bilyk, Bohdan, Kim, Sora, Fazal, Asif, Baker, Tania A., Seipke, Ryan F.
Publicado 2020

The SspB adaptor drives structural changes in the AAA+ ClpXP protease during ssrA-tagged substrate delivery

por Ghanbarpour, Alireza, Fei, Xue, Baker, Tania A., Davis, Joseph H., Sauer, Robert T.
Publicado 2023

Mechanochemical basis of protein degradation by a double-ring AAA+ machine

por Olivares, Adrian O., Nager, Andrew R., Iosefson, Ohad, Sauer, Robert T., Baker, Tania A.
Publicado 2014

Subunit asymmetry and roles of conformational switching in the hexameric AAA+ ring of ClpX

por Stinson, Benjamin M., Baytshtok, Vladimir, Schmitz, Karl R., Baker, Tania A., Sauer, Robert T.
Publicado 2015

Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates

por Fei, Xue, Bell, Tristan A, Barkow, Sarah R, Baker, Tania A, Sauer, Robert T
Publicado 2020

ClpAP proteolysis does not require rotation of the ClpA unfoldase relative to ClpP

por Kim, Sora, Zuromski, Kristin L, Bell, Tristan A, Sauer, Robert T, Baker, Tania A
Publicado 2020

NOA1, a Novel ClpXP Substrate, Takes an Unexpected Nuclear Detour Prior to Mitochondrial Import

por Al-Furoukh, Natalie, Kardon, Julia R., Krüger, Marcus, Szibor, Marten, Baker, Tania A., Braun, Thomas
Publicado 2014

Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate

por Fei, Xue, Bell, Tristan A, Jenni, Simon, Stinson, Benjamin M, Baker, Tania A, Harrison, Stephen C, Sauer, Robert T
Publicado 2020

Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug

por Baytshtok, Vladimir, Fei, Xue, Shih, Tsai-Ting, Grant, Robert A., Santos, Justin C., Baker, Tania A., Sauer, Robert T.
Publicado 2021