Cervical Sympathetic Chain Schwannoma Masquerading as a Vagus Nerve Schwannoma Complicated by Postoperative Horner’s Syndrome and Facial Pain: A Case Report

por Baker, Austin T., Homewood, Tyler J., Baker, Terry R.
Publicado 2018

Improving B-cell epitope prediction and its application to global antibody-antigen docking

por Krawczyk, Konrad, Liu, Xiaofeng, Baker, Terry, Shi, Jiye, Deane, Charlotte M.
Publicado 2014

Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations

por Wong, Mabel T. Y., Kelm, Sebastian, Liu, Xiaofeng, Taylor, Richard D., Baker, Terry, Essex, Jonathan W.
Publicado 2022

Corrigendum: Higher Affinity Antibodies Bind With Lower Hydration and Flexibility in Large Scale Simulations

por Wong, Mabel T. Y., Kelm, Sebastian, Liu, Xiaofeng, Taylor, Richard D., Baker, Terry, Essex, Jonathan W.
Publicado 2022

Anti-AMPA Receptor Autoantibodies Reduce Excitatory Currents in Rat Hippocampal Neurons

por Day, Charlotte, Silva, John-Paul, Munro, Rebecca, Baker, Terry S., Wolff, Christian, Bithell, Angela, Stephens, Gary J.
Publicado 2023

SAbDab: the structural antibody database

por Dunbar, James, Krawczyk, Konrad, Leem, Jinwoo, Baker, Terry, Fuchs, Angelika, Georges, Guy, Shi, Jiye, Deane, Charlotte M.
Publicado 2014

Creation of a gated antibody as a conditionally functional synthetic protein

por Gunnoo, Smita B., Finney, Helene M., Baker, Terry S., Lawson, Alastair D., Anthony, Daniel C., Davis, Benjamin G.
Publicado 2014

Length-independent structural similarities enrich the antibody CDR canonical class model

por Nowak, Jaroslaw, Baker, Terry, Georges, Guy, Kelm, Sebastian, Klostermann, Stefan, Shi, Jiye, Sridharan, Sudharsan, Deane, Charlotte M.
Publicado 2016

High-resolution structural information of membrane-bound α-synuclein provides insight into the MoA of the anti-Parkinson drug UCB0599

por Schwarz, Thomas C., Beier, Andreas, Ledolter, Karin, Gossenreiter, Thomas, Höfurthner, Theresa, Hartl, Markus, Baker, Terry S., Taylor, Richard J., Konrat, Robert
Publicado 2023

Computational design of an epitope-specific Keap1 binding antibody using hotspot residues grafting and CDR loop swapping

por Liu, Xiaofeng, Taylor, Richard D., Griffin, Laura, Coker, Shu-Fen, Adams, Ralph, Ceska, Tom, Shi, Jiye, Lawson, Alastair D. G., Baker, Terry
Publicado 2017

Membrane Interactions of α-Synuclein Revealed by Multiscale Molecular Dynamics Simulations, Markov State Models, and NMR

por Amos, Sarah-Beth T. A., Schwarz, Thomas C., Shi, Jiye, Cossins, Benjamin P., Baker, Terry S., Taylor, Richard J., Konrat, Robert, Sansom, Mark S. P.
Publicado 2021

Engineering synucleinopathy‐resistant human dopaminergic neurons by CRISPR‐mediated deletion of the SNCA gene

por Chen, Yixi, Dolt, Karamjit Singh, Kriek, Marco, Baker, Terry, Downey, Patrick, Drummond, Nicola J., Canham, Maurice A., Natalwala, Ammar, Rosser, Susan, Kunath, Tilo
Publicado 2018

Bimekizumab, a Novel Humanized IgG1 Antibody That Neutralizes Both IL-17A and IL-17F

por Adams, Ralph, Maroof, Asher, Baker, Terry, Lawson, Alastair D. G., Oliver, Ruth, Paveley, Ross, Rapecki, Steve, Shaw, Stevan, Vajjah, Pavan, West, Shauna, Griffiths, Meryn
Publicado 2020

Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum hal...

por Adams, Ralph, Griffin, Laura, Compson, Joanne E., Jairaj, Mark, Baker, Terry, Ceska, Tom, West, Shauna, Zaccheo, Oliver, Davé, Emma, Lawson, Alastair DG., Humphreys, David P., Heywood, Sam
Publicado 2016

Discovery and characterization of olokizumab: A humanized antibody targeting interleukin-6 and neutralizing gp130-signaling

por Shaw, Stevan, Bourne, Tim, Meier, Chris, Carrington, Bruce, Gelinas, Rich, Henry, Alistair, Popplewell, Andrew, Adams, Ralph, Baker, Terry, Rapecki, Steve, Marshall, Diane, Moore, Adrian, Neale, Helen, Lawson, Alastair
Publicado 2014

Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F co...

por Glatt, Sophie, Baeten, Dominique, Baker, Terry, Griffiths, Meryn, Ionescu, Lucian, Lawson, Alastair D G, Maroof, Ash, Oliver, Ruth, Popa, Serghei, Strimenopoulou, Foteini, Vajjah, Pavan, Watling, Mark I L, Yeremenko, Nataliya, Miossec, Pierre, Shaw, Stevan
Publicado 2018

Epitope determines efficacy of therapeutic anti-Tau antibodies in a functional assay with human Alzheimer Tau

por Courade, Jean-Philippe, Angers, Rachel, Mairet-Coello, Georges, Pacico, Nathalie, Tyson, Kerry, Lightwood, Daniel, Munro, Rebecca, McMillan, David, Griffin, Robert, Baker, Terry, Starkie, Dale, Nan, Ruodan, Westwood, Marta, Mushikiwabo, Marie-Laetitia, Jung, Sophie, Odede, Geofrey, Sweeney, Berni, Popplewell, Andrew, Burgess, Gillian, Downey, Patrick, Citron, Martin
Publicado 2018

Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling

por Adams, Ralph, Burnley, Rebecca J., Valenzano, Chiara R., Qureshi, Omar, Doyle, Carl, Lumb, Simon, del Carmen Lopez, Maria, Griffin, Robert, McMillan, David, Taylor, Richard D., Meier, Chris, Mori, Prashant, Griffin, Laura M., Wernery, Ulrich, Kinne, Jörg, Rapecki, Stephen, Baker, Terry S., Lawson, Alastair D. G., Wright, Michael, Ettorre, Anna
Publicado 2017