The role of R-spondin proteins in cancer biology

por ter Steege, Eline J., Bakker, Elvira R. M.
Publicado 2021

IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation

por Ikink, Gerjon J., Boer, Mandy, Bakker, Elvira R. M., Hilkens, John
Publicado 2016

LGR6-dependent conditional inactivation of E-cadherin and p53 leads to invasive skin and mammary carcinomas in mice

por ter Steege, Eline J., Sijnesael, Thijmen, Enserink, Lotte, Klarenbeek, Sjoerd, Haakma, Wisse E., Bakker, Elvira R.M., Derksen, Patrick W.B.
Publicado 2022

Dichotomal effect of space flight-associated microgravity on stress-activated protein kinases in innate immunity

por Verhaar, Auke P., Hoekstra, Elmer, Tjon, Angela S. W., Utomo, Wesley K., Deuring, J. Jasper, Bakker, Elvira R. M., Muncan, Vanesa, Peppelenbosch, Maikel P.
Publicado 2014

Insertional mutagenesis in a HER2-positive breast cancer model reveals ERAS as a driver of cancer and therapy resistance

por Ikink, Gerjon J., Boer, Mandy, Bakker, Elvira R. M., Vendel-Zwaagstra, Annabel, Klijn, Chris, ten Hoeve, Jelle, Jonkers, Jos, Wessels, Lodewyk F., Hilkens, John
Publicado 2018

RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis

por Hilkens, John, Timmer, Nikki C, Boer, Mandy, Ikink, Gerjon J, Schewe, Matthias, Sacchetti, Andrea, Koppens, Martijn A J, Song, Ji-Ying, Bakker, Elvira R M
Publicado 2017

Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice

por Lyraki, Rodanthi, Grabek, Anaëlle, Tison, Amélie, Weerasinghe Arachchige, Lahiru Chamara, Peitzsch, Mirko, Bechmann, Nicole, Youssef, Sameh A., de Bruin, Alain, Bakker, Elvira R. M., Claessens, Frank, Chaboissier, Marie-Christine, Schedl, Andreas
Publicado 2023

Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation

por Koopmans, Tim, Hesse, Laura, Nawijn, Martijn C., Kumawat, Kuldeep, Menzen, Mark H., Sophie T. Bos, I., Smits, Ron, Bakker, Elvira R. M., van den Berge, Maarten, Koppelman, Gerard H., Guryev, Victor, Gosens, Reinoud
Publicado 2020

β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis

por van Veelen, Wendy, Le, Ngoc H, Helvensteijn, Werner, Blonden, Lau, Theeuwes, Myrte, Bakker, Elvira R M, Franken, Patrick F, van Gurp, Léon, Meijlink, Frits, van der Valk, Martin A, Kuipers, Ernst J, Fodde, Riccardo, Smits, Ron
Publicado 2011

Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer

por Rätze, Max A. K., Koorman, Thijs, Sijnesael, Thijmen, Bassey-Archibong, Blessing, van de Ven, Robert, Enserink, Lotte, Visser, Daan, Jaksani, Sridevi, Viciano, Ignacio, Bakker, Elvira R. M., Richard, François, Tutt, Andrew, O’Leary, Lynda, Fitzpatrick, Amanda, Roca-Cusachs, Pere, van Diest, Paul J., Desmedt, Christine, Daniel, Juliet M., Isacke, Clare M., Derksen, Patrick W. B.
Publicado 2022

Correction: Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer

por Rätze, Max A. K., Koorman, Thijs, Sijnesael, Thijmen, Bassey-Archibong, Blessing, van de Ven, Robert, Enserink, Lotte, Visser, Daan, Jaksani, Sridevi, Viciano, Ignacio, Bakker, Elvira R. M., Richard, François, Tutt, Andrew, O’Leary, Lynda, Fitzpatrick, Amanda, Roca-Cusachs, Pere, van Diest, Paul J., Desmedt, Christine, Daniel, Juliet M., Isacke, Clare M., Derksen, Patrick W. B.
Publicado 2022