Domoic Acid-Induced Neurotoxicity Is Mainly Mediated by the AMPA/KA Receptor: Comparison between Immature and Mature Primary Cultures of Neurons and Glial Cells from Rat Cerebellum

por Hogberg, Helena T., Bal-Price, Anna K.
Publicado 2011

Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity

por Bal-Price, Anna, Meek, M.E. (Bette)
Publicado 2017

Development of the Adverse Outcome Pathway (AOP): Chronic binding of antagonist to N-methyl-d-aspartate receptors (NMDARs) during brain development induces impairment of learning a...

por Sachana, Magdalini, Rolaki, Alexandra, Bal-Price, Anna
Publicado 2018

The potential of mechanistic information organised within the AOP framework to increase regulatory uptake of the developmental neurotoxicity (DNT) in vitro battery of assays

por Sachana, Magdalini, Willett, Catherine, Pistollato, Francesca, Bal-Price, Anna
Publicado 2021

Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods

por Bal-Price, Anna, Pistollato, Francesca, Sachana, Magdalini, Bopp, Stephanie K., Munn, Sharon, Worth, Andrew
Publicado 2018

Integrating biokinetics and in vitro studies to evaluate developmental neurotoxicity induced by chlorpyrifos in human iPSC-derived neural stem cells undergoing differentiation towa...

por Di Consiglio, Emma, Pistollato, Francesca, Mendoza-De Gyves, Emilio, Bal-Price, Anna, Testai, Emanuela
Publicado 2020

Assessment of neurotransmitter release in human iPSC-derived neuronal/glial cells: a missing in vitro assay for regulatory developmental neurotoxicity testing

por Cervetto, Chiara, Pistollato, Francesca, Amato, Sarah, Mendoza-de Gyves, Emilio, Bal-Price, Anna, Maura, Guido, Marcoli, Manuela
Publicado 2023

An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition

por Terron, Andrea, Bal-Price, Anna, Paini, Alicia, Monnet-Tschudi, Florianne, Bennekou, Susanne Hougaard, Leist, Marcel, Schildknecht, Stefan
Publicado 2017

Assessment of developmental neurotoxicity induced by chemical mixtures using an adverse outcome pathway concept

por Pistollato, Francesca, de Gyves, Emilio Mendoza, Carpi, Donatella, Bopp, Stephanie K., Nunes, Carolina, Worth, Andrew, Bal-Price, Anna
Publicado 2020

Combining in vitro assays and mathematical modelling to study developmental neurotoxicity induced by chemical mixtures

por Pistollato, Francesca, Carpi, Donatella, Mendoza-de Gyves, Emilio, Paini, Alicia, Bopp, Stephanie K., Worth, Andrew, Bal-Price, Anna
Publicado 2021

Prediction of in vivo prenatal chlorpyrifos exposure leading to developmental neurotoxicity in humans based on in vitro toxicity data by quantitative in vitro–in vivo extrapolation...

por Algharably, Engi Abdelhady, Di Consiglio, Emma, Testai, Emanuela, Pistollato, Francesca, Bal-Price, Anna, Najjar, Abdulkarim, Kreutz, Reinhold, Gundert-Remy, Ursula
Publicado 2023

Genomic and Phenotypic Alterations of the Neuronal-Like Cells Derived from Human Embryonal Carcinoma Stem Cells (NT2) Caused by Exposure to Organophosphorus Compounds Paraoxon and...

por Pamies, David, Sogorb, Miguel A., Fabbri, Marco, Gribaldo, Laura, Collotta, Angelo, Scelfo, Bibiana, Vilanova, Eugenio, Harris, Georgina, Bal-Price, Anna
Publicado 2014

Exposure to human relevant mixtures of halogenated persistent organic pollutants (POPs) alters neurodevelopmental processes in human neural stem cells undergoing differentiation

por Davidsen, Nichlas, Lauvås, Anna Jacobsen, Myhre, Oddvar, Ropstad, Erik, Carpi, Donatella, Gyves, Emilio Mendoza-de, Berntsen, Hanne Friis, Dirven, Hubert, Paulsen, Ragnhild E, Bal-Price, Anna, Pistollato, Francesca
Publicado 2021

Current EU regulatory requirements for the assessment of chemicals and cosmetic products: challenges and opportunities for introducing new approach methodologies

por Pistollato, Francesca, Madia, Federica, Corvi, Raffaella, Munn, Sharon, Grignard, Elise, Paini, Alicia, Worth, Andrew, Bal-Price, Anna, Prieto, Pilar, Casati, Silvia, Berggren, Elisabet, Bopp, Stephanie K, Zuang, Valérie
Publicado 2021

Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network

por Spînu, Nicoleta, Cronin, Mark T.D., Lao, Junpeng, Bal-Price, Anna, Campia, Ivana, Enoch, Steven J., Madden, Judith C., Mora Lagares, Liadys, Novič, Marjana, Pamies, David, Scholz, Stefan, Villeneuve, Daniel L., Worth, Andrew P.
Publicado 2022

Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use

por Aschner, Michael, Ceccatelli, Sandra, Daneshian, Mardas, Fritsche, Ellen, Hasiwa, Nina, Hartung, Thomas, Hogberg, Helena T., Leist, Marcel, Li, Abby, Mundy, William R., Padilla, Stephanie, Piersma, Aldert H., Bal-Price, Anna, Seiler, Andrea, Westerink, Remco H., Zimmer, Bastian, Lein, Pamela J.
Publicado 2016

The Adverse Outcome Pathway Framework Applied to Neurological Symptoms of COVID-19

por Hogberg, Helena T., Lam, Ann, Ohayon, Elan, Shahbaz, Muhammad Ali, Clerbaux, Laure-Alix, Bal-Price, Anna, Coecke, Sandra, Concha, Rachel, De Bernardi, Francesca, Edrosa, Eizleayne, Hargreaves, Alan J., Kanninen, Katja M., Munoz, Amalia, Pistollato, Francesca, Saravanan, Surat, Garcia-Reyero, Natàlia, Wittwehr, Clemens, Sachana, Magdalini
Publicado 2022

Workgroup Report: Incorporating In Vitro Alternative Methods for Developmental Neurotoxicity into International Hazard and Risk Assessment Strategies

por Coecke, Sandra, Goldberg, Alan M, Allen, Sandra, Buzanska, Leonora, Calamandrei, Gemma, Crofton, Kevin, Hareng, Lars, Hartung, Thomas, Knaut, Holger, Honegger, Paul, Jacobs, Miriam, Lein, Pamela, Li, Abby, Mundy, William, Owen, David, Schneider, Steffen, Silbergeld, Ellen, Reum, Torsten, Trnovec, Tomas, Monnet-Tschudi, Florianne, Bal-Price, Anna
Publicado 2007

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

por Fritsche, Ellen, Grandjean, Philippe, Crofton, Kevin M., Aschner, Michael, Goldberg, Alan, Heinonen, Tuula, Hessel, Ellen V.S., Hogberg, Helena T., Bennekou, Susanne Hougaard, Lein, Pamela J., Leist, Marcel, Mundy, William R., Paparella, Martin, Piersma, Aldert H., Sachana, Magdalini, Schmuck, Gabriele, Solecki, Roland, Terron, Andrea, Monnet-Tschudi, Florianne, Wilks, Martin F., Witters, Hilda, Zurich, Marie-Gabrielle, Bal-Price, Anna
Publicado 2018

International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes

por Bal-Price, Anna, Crofton, Kevin M., Leist, Marcel, Allen, Sandra, Arand, Michael, Buetler, Timo, Delrue, Nathalie, FitzGerald, Rex E., Hartung, Thomas, Heinonen, Tuula, Hogberg, Helena, Bennekou, Susanne Hougaard, Lichtensteiger, Walter, Oggier, Daniela, Paparella, Martin, Axelstad, Marta, Piersma, Aldert, Rached, Eva, Schilter, Benoît, Schmuck, Gabriele, Stoppini, Luc, Tongiorgi, Enrico, Tiramani, Manuela, Monnet-Tschudi, Florianne, Wilks, Martin F., Ylikomi, Timo, Fritsche, Ellen
Publicado 2015