Targeting Energy Metabolism in Mycobacterium tuberculosis, a New Paradigm in Antimycobacterial Drug Discovery

por Bald, Dirk, Villellas, Cristina, Lu, Ping, Koul, Anil
Publicado 2017

Probing the Interaction of the Diarylquinoline TMC207 with Its Target Mycobacterial ATP Synthase

por Haagsma, Anna C., Podasca, Ioana, Koul, Anil, Andries, Koen, Guillemont, Jerome, Lill, Holger, Bald, Dirk
Publicado 2011

The anti-mycobacterial activity of the cytochrome bcc inhibitor Q203 can be enhanced by small-molecule inhibition of cytochrome bd

por Lu, Ping, Asseri, Amer H., Kremer, Martijn, Maaskant, Janneke, Ummels, Roy, Lill, Holger, Bald, Dirk
Publicado 2018

Two-stimuli manipulation of a biological motor

por Ristic, Zorica, Vitali, Marco, Duci, Alessandro, Goetze, Christian, Kemnitz, Klaus, Zuschratter, Werner, Lill, Holger, Bald, Dirk
Publicado 2009

Cytochrome bd Displays Significant Quinol Peroxidase Activity

por Al-Attar, Sinan, Yu, Yuanjie, Pinkse, Martijn, Hoeser, Jo, Friedrich, Thorsten, Bald, Dirk, de Vries, Simon
Publicado 2016

The cytochrome bd-type quinol oxidase is important for survival of Mycobacterium smegmatis under peroxide and antibiotic-induced stress

por Lu, Ping, Heineke, Marieke H., Koul, Anil, Andries, Koen, Cook, Gregory M., Lill, Holger, van Spanning, Rob, Bald, Dirk
Publicado 2015

Direct quantitative detection of Doc2b-induced hemifusion in optically trapped membranes

por Brouwer, Ineke, Giniatullina, Asiya, Laurens, Niels, van Weering, Jan R. T., Bald, Dirk, Wuite, Gijs J. L., Groffen, Alexander J.
Publicado 2015

A fluorescence-based reporter for monitoring expression of mycobacterial cytochrome bd in response to antibacterials and during infection

por Boot, Maikel, Jim, Kin Ki, Liu, Ting, Commandeur, Susanna, Lu, Ping, Verboom, Theo, Lill, Holger, Bitter, Wilbert, Bald, Dirk
Publicado 2017

Cardiolipin enhances the enzymatic activity of cytochrome bd and cytochrome bo(3) solubilized in dodecyl-maltoside

por Asseri, Amer H., Godoy-Hernandez, Albert, Goojani, Hojjat Ghasemi, Lill, Holger, Sakamoto, Junshi, McMillan, Duncan G. G., Bald, Dirk
Publicado 2021

Response of Mycobacterium smegmatis to the Cytochrome bcc Inhibitor Q203

por Chauhan, Priyanka, van der Meulen, Santhe Amber, Simões Caetano, João Miguel, Goojani, Hojjat Ghasemi, Botman, Dennis, van Spanning, Rob, Lill, Holger, Bald, Dirk
Publicado 2022

Rapid and Highly Stable Membrane Reconstitution by LAiR Enables the Study of Physiological Integral Membrane Protein Functions

por Godoy-Hernandez, Albert, Asseri, Amer H., Purugganan, Aiden J., Jiko, Chimari, de Ram, Carol, Lill, Holger, Pabst, Martin, Mitsuoka, Kaoru, Gerle, Christoph, Bald, Dirk, McMillan, Duncan G. G.
Publicado 2023

Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism

por Koul, Anil, Vranckx, Luc, Dhar, Neeraj, Göhlmann, Hinrich W.H., Özdemir, Emre, Neefs, Jean-Marc, Schulz, Melanie, Lu, Ping, Mørtz, Ejvind, McKinney, John D., Andries, Koen, Bald, Dirk
Publicado 2014

Dissecting the conformational complexity and mechanism of a bacterial heme transporter

por Wu, Di, Mehdipour, Ahmad R., Finke, Franziska, Goojani, Hojjat G., Groh, Roan R., Grund, Tamara N., Reichhart, Thomas M. B., Zimmermann, Rita, Welsch, Sonja, Bald, Dirk, Shepherd, Mark, Hummer, Gerhard, Safarian, Schara
Publicado 2023

Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II oxidases

por Radloff, Melanie, Elamri, Isam, Grund, Tamara N., Witte, Luca F., Hohmann, Katharina F., Nakagaki, Sayaka, Goojani, Hojjat G., Nasiri, Hamid, Hideto Miyoshi, Bald, Dirk, Xie, Hao, Sakamoto, Junshi, Schwalbe, Harald, Safarian, Schara
Publicado 2021