Interleukin-1 receptor–associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling

por De Nardo, Dominic, Balka, Katherine R., Cardona Gloria, Yamel, Rao, Vikram R., Latz, Eicke, Masters, Seth L.
Publicado 2018

Genistein Targets STING-Driven Antiviral Responses

por Ullah, Tomalika R., Balka, Katherine R., Ambrose, Rebecca L., Pépin, Geneviève, Wilce, Matthew C. J., Wilce, Jacqueline A., Thomas, Belinda J., De Nardo, Dominic, Williams, Bryan R. G., Gantier, Michael P.
Publicado 2022

A Mutation Outside the Dimerization Domain Causing Atypical STING-Associated Vasculopathy With Onset in Infancy

por Saldanha, Rohit G., Balka, Katherine R., Davidson, Sophia, Wainstein, Brynn K., Wong, Melanie, Macintosh, Rebecca, Loo, Christine K. C., Weber, Martin A., Kamath, Vasanth, Moghaddas, Fiona, De Nardo, Dominic, Gray, Paul Edgar, Masters, Seth Lucian
Publicado 2018

Termination of STING responses is mediated via ESCRT‐dependent degradation

por Balka, Katherine R, Venkatraman, Rajan, Saunders, Tahnee L, Shoppee, Angus, Pang, Ee Shan, Magill, Zoe, Homman‐Ludiye, Jihane, Huang, Cheng, Lane, Rachael M, York, Harrison M, Tan, Peck, Schittenhelm, Ralf B, Arumugam, Senthil, Kile, Benjamin T, O'Keeffe, Meredith, De Nardo, Dominic
Publicado 2023

Connexin-Dependent Transfer of cGAMP to Phagocytes Modulates Antiviral Responses

por Pépin, Geneviève, De Nardo, Dominic, Rootes, Christina L., Ullah, Tomalika R., Al-Asmari, Sumaiah S., Balka, Katherine R., Li, Hong-Mei, Quinn, Kylie M., Moghaddas, Fiona, Chappaz, Stephane, Kile, Benjamin T., Morand, Eric F., Masters, Seth L., Stewart, Cameron R., Williams, Bryan R. G., Gantier, Michael P.
Publicado 2020

Discordance in STING-Induced Activation and Cell Death Between Mouse and Human Dendritic Cell Populations

por Pang, Ee Shan, Daraj, Ghazal, Balka, Katherine R., De Nardo, Dominic, Macri, Christophe, Hochrein, Hubertus, Masterman, Kelly-Anne, Tan, Peck S., Shoppee, Angus, Magill, Zoe, Jahan, Nazneen, Bafit, Mariam, Zhan, Yifan, Kile, Benjamin T., Lawlor, Kate E., Radford, Kristen J., Wright, Mark D., O’Keeffe, Meredith
Publicado 2022

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

por Yu, Chien-Hsiung, Davidson, Sophia, Harapas, Cassandra R., Hilton, James B., Mlodzianoski, Michael J., Laohamonthonkul, Pawat, Louis, Cynthia, Low, Ronnie Ren Jie, Moecking, Jonas, De Nardo, Dominic, Balka, Katherine R., Calleja, Dale J., Moghaddas, Fiona, Ni, Erya, McLean, Catriona A., Samson, Andre L., Tyebji, Shiraz, Tonkin, Christopher J., Bye, Christopher R., Turner, Bradley J., Pepin, Genevieve, Gantier, Michael P., Rogers, Kelly L., McArthur, Kate, Crouch, Peter J., Masters, Seth L.
Publicado 2020

Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection

por Ullah, Tomalika R., Johansen, Matt D., Balka, Katherine R., Ambrose, Rebecca L., Gearing, Linden J., Roest, James, Vivian, Julian P., Sapkota, Sunil, Jayasekara, W. Samantha N., Wenholz, Daniel S., Aldilla, Vina R., Zeng, Jun, Miemczyk, Stefan, Nguyen, Duc H., Hansbro, Nicole G., Venkatraman, Rajan, Kang, Jung Hee, Pang, Ee Shan, Thomas, Belinda J., Alharbi, Arwaf S., Rezwan, Refaya, O’Keeffe, Meredith, Donald, William A., Ellyard, Julia I., Wong, Wilson, Kumar, Naresh, Kile, Benjamin T., Vinuesa, Carola G., Kelly, Graham E., Laczka, Olivier F., Hansbro, Philip M., De Nardo, Dominic, Gantier, Michael P.
Publicado 2023