Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent

por Ball, Daniel P., Lewis, Andrew M., Williams, Declan, Resetca, Diana, Wilson, Derek J., Gunning, Patrick T.
Publicado 2016

DPP8/9 inhibitors are universal activators of functional NLRP1 alleles

por Gai, Kuo, Okondo, Marian C., Rao, Sahana D., Chui, Ashley J., Ball, Daniel P., Johnson, Darren C., Bachovchin, Daniel A.
Publicado 2019

DPP9’s Enzymatic Activity and Not Its Binding to CARD8 Inhibits Inflammasome Activation

por Griswold, Andrew R., Ball, Daniel P., Bhattacharjee, Abir, Chui, Ashley J., Rao, Sahana D., Taabazuing, Cornelius Y., Bachovchin, Daniel A.
Publicado 2019

DPP8/9 inhibitors activate the CARD8 inflammasome in resting lymphocytes

por Johnson, Darren C., Okondo, Marian C., Orth, Elizabeth L., Rao, Sahana D., Huang, Hsin-Che, Ball, Daniel P., Bachovchin, Daniel A.
Publicado 2020

Activation of the CARD8 Inflammasome Requires a Disordered Region

por Chui, Ashley J., Griswold, Andrew R., Taabazuing, Cornelius Y., Orth, Elizabeth L., Gai, Kuo, Rao, Sahana D., Ball, Daniel P., Hsiao, Jeffrey C., Bachovchin, Daniel A.
Publicado 2020

The NLRP1 and CARD8 inflammasomes detect reductive stress

por Wang, Qinghui, Hsiao, Jeffrey C., Yardeny, Noah, Huang, Hsin-Che, O’Mara, Claire M., Orth-He, Elizabeth L., Ball, Daniel P., Zhang, Ze, Bachovchin, Daniel A.
Publicado 2023

Caspase-1 interdomain linker cleavage is required for pyroptosis

por Ball, Daniel P, Taabazuing, Cornelius Y, Griswold, Andrew R, Orth, Elizabeth L, Rao, Sahana D, Kotliar, Ilana B, Vostal, Lauren E, Johnson, Darren C, Bachovchin, Daniel A
Publicado 2020

A ubiquitin-independent proteasome pathway controls activation of the CARD8 inflammasome

por Hsiao, Jeffrey C., Neugroschl, Atara R., Chui, Ashley J., Taabazuing, Cornelius Y., Griswold, Andrew R., Wang, Qinghui, Huang, Hsin-Che, Orth-He, Elizabeth L., Ball, Daniel P., Hiotis, Giorgos, Bachovchin, Daniel A.
Publicado 2022