Strategies for clinical dose optimization of T cell-engaging therapies in oncology

por Ball, Kathryn, Dovedi, Simon J, Vajjah, Pavan, Phipps, Alex
Publicado 2023

A case report on a rare presentation of adrenal myelolipoma with low-impact traumatic haemorrhage and the challenges of conservative management

por Paice, Bronte, Oyebola, Taiwo, Ball, Kathryn, Alexander, Shaun, Sherwood, Benedict
Publicado 2022

Generation of a CHIP isogenic human iPSC-derived cortical neuron model for functional proteomics

por Dias, Catarina, Nita, Erisa, Faktor, Jakub, Hernychova, Lenka, Kunath, Tilo, Ball, Kathryn L.
Publicado 2022

Development of and insights from systems pharmacology models of antibody‐drug conjugates

por Lam, Inez, Pilla Reddy, Venkatesh, Ball, Kathryn, Arends, Rosalinda H., Mac Gabhann, Feilim
Publicado 2022

Rearrangement of mitochondrial pyruvate dehydrogenase subunit dihydrolipoamide dehydrogenase protein–protein interactions by the MDM2 ligand nutlin‐3

por Way, Luke, Faktor, Jakub, Dvorakova, Petra, Nicholson, Judith, Vojtesek, Borek, Graham, Duncan, Ball, Kathryn L., Hupp, Ted
Publicado 2016

Molecular dynamics simulations of site point mutations in the TPR domain of cyclophilin 40 identify conformational states with distinct dynamic and enzymatic properties

por Gur, Mert, Blackburn, Elizabeth A., Ning, Jia, Narayan, Vikram, Ball, Kathryn L., Walkinshaw, Malcolm D., Erman, Burak
Publicado 2018

Cyclophilin40 isomerase activity is regulated by a temperature-dependent allosteric interaction with Hsp90

por Blackburn, Elizabeth A., Wear, Martin A., Landré, Vivian, Narayan, Vikram, Ning, Jia, Erman, Burak, Ball, Kathryn L., Walkinshaw, Malcolm D.
Publicado 2015

Protein–Protein Interactions Modulate the Docking-Dependent E3-Ubiquitin Ligase Activity of Carboxy-Terminus of Hsc70-Interacting Protein (CHIP)

por Narayan, Vikram, Landré, Vivien, Ning, Jia, Hernychova, Lenka, Muller, Petr, Verma, Chandra, Walkinshaw, Malcolm D., Blackburn, Elizabeth A., Ball, Kathryn L.
Publicado 2015

CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity

por Dias, Catarina, Nita, Erisa, Faktor, Jakub, Tynan, Ailish C., Hernychova, Lenka, Vojtesek, Borivoj, Nylandsted, Jesper, Hupp, Ted R., Kunath, Tilo, Ball, Kathryn L.
Publicado 2021

CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity

por Dias, Catarina, Nita, Erisa, Faktor, Jakub, Tynan, Ailish C., Hernychova, Lenka, Vojtesek, Borivoj, Nylandsted, Jesper, Hupp, Ted R., Kunath, Tilo, Ball, Kathryn L.
Publicado 2022

The effects of IFITM1 and IFITM3 gene deletion on IFNγ stimulated protein synthesis

por Gómez-Herranz, Maria, Nekulova, Marta, Faktor, Jakub, Hernychova, Lenka, Kote, Sachin, Sinclair, Elizabeth H., Nenutil, Rudolf, Vojtesek, Borivoj, Ball, Kathryn L., Hupp, Ted R.
Publicado 2019

Emergent Role of IFITM1/3 towards Splicing Factor (SRSF1) and Antigen-Presenting Molecule (HLA-B) in Cervical Cancer

por Gómez-Herranz, Maria, Faktor, Jakub, Yébenes Mayordomo, Marcos, Pilch, Magdalena, Nekulova, Marta, Hernychova, Lenka, Ball, Kathryn L., Vojtesek, Borivoj, Hupp, Ted R., Kote, Sachin
Publicado 2022

Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans

por Goya, María Eugenia, Xue, Feng, Sampedro-Torres-Quevedo, Cristina, Arnaouteli, Sofia, Riquelme-Dominguez, Lourdes, Romanowski, Andrés, Brydon, Jack, Ball, Kathryn L., Stanley-Wall, Nicola R., Doitsidou, Maria
Publicado 2020

Multiplex Bioanalytical Methods for Comprehensive Characterization and Quantification of the Unique Complementarity-Determining-Region Deamidation of MEDI7247, an Anti-ASCT2 Pyrrol...

por Huang, Yue, Yuan, Jiaqi, Mu, Ruipeng, Kubiak, Robert J., Ball, Kathryn, Cao, Mingyan, Hussmann, G. Patrick, de Mel, Niluka, Liu, Dengfeng, Roskos, Lorin K., Liang, Meina, Rosenbaum, Anton I.
Publicado 2023

The MDM2 ligand Nutlin-3 differentially alters expression of the immune blockade receptors PD-L1 and CD276

por Li, Ruidong, Zatloukalova, Pavlina, Muller, Petr, Gil-Mir, Maria, Kote, Sachin, Wilkinson, Simon, Kemp, Alain J., Hernychova, Lenka, Wang, Yaxin, Ball, Kathryn L., Tao, Kaixiong, Hupp, Ted, Vojtesek, Borivoj
Publicado 2020

Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site

por Kalathiya, Umesh, Padariya, Monikaben, Mayordomo, Marcos, Lisowska, Małgorzata, Nicholson, Judith, Singh, Ashita, Baginski, Maciej, Fahraeus, Robin, Carragher, Neil, Ball, Kathryn, Haas, Juergen, Daniels, Alison, Hupp, Ted R., Alfaro, Javier Antonio
Publicado 2020

Identification of novel interferon responsive protein partners of human leukocyte antigen A (HLA-A) using cross-linking mass spectrometry (CLMS) approach

por Singh, Ashita, Padariya, Monikaben, Faktor, Jakub, Kote, Sachin, Mikac, Sara, Dziadosz, Alicja, Lam, Tak W., Brydon, Jack, Wear, Martin A., Ball, Kathryn L., Hupp, Ted, Sznarkowska, Alicja, Vojtesek, Borek, Kalathiya, Umesh
Publicado 2022

Kinomics platform using GBM tissue identifies BTK as being associated with higher patient survival

por Al Shboul, Sofian, Curran, Olimpia E, Alfaro, Javier A, Lickiss, Fiona, Nita, Erisa, Kowalski, Jacek, Naji, Faris, Nenutil, Rudolf, Ball, Kathryn L, Krejcir, Radovan, Vojtesek, Borivoj, Hupp, Ted R, Brennan, Paul M
Publicado 2021

Next-generation sequencing of a combinatorial peptide phage library screened against ubiquitin identifies peptide aptamers that can inhibit the in vitro ubiquitin transfer cascade

por Lisowska, Małgorzata, Lickiss, Fiona, Gil-Mir, Maria, Huart, Anne-Sophie, Trybala, Zuzanna, Way, Luke, Hernychova, Lenka, Krejci, Adam, Muller, Petr, Krejcir, Radovan, Zhukow, Igor, Jurczak, Przemyslaw, Rodziewicz-Motowidło, Sylwia, Ball, Kathryn, Vojtesek, Borivoj, Hupp, Ted, Kalathiya, Umesh
Publicado 2022

The Development of a Recombinant scFv Monoclonal Antibody Targeting Canine CD20 for Use in Comparative Medicine

por Jain, Saurabh, Aresu, Luca, Comazzi, Stefano, Shi, Jianguo, Worrall, Erin, Clayton, John, Humphries, William, Hemmington, Sandra, Davis, Paul, Murray, Euan, Limeneh, Asmare A., Ball, Kathryn, Ruckova, Eva, Muller, Petr, Vojtesek, Borek, Fahraeus, Robin, Argyle, David, Hupp, Ted R.
Publicado 2016