GABA(A) receptors as targets for anaesthetics and analgesics and promising candidates to help treat coronavirus infections: A mini‐review

por Luo, Yujia, Balle, Thomas
Publicado 2022

Computer-Aided Drug Design towards New Psychotropic and Neurological Drugs

por Dorahy, Georgia, Chen, Jake Zheng, Balle, Thomas
Publicado 2023

CardioTox net: a robust predictor for hERG channel blockade based on deep learning meta-feature ensembles

por Karim, Abdul, Lee, Matthew, Balle, Thomas, Sattar, Abdul
Publicado 2021

Concatenated nicotinic acetylcholine receptors: A gift or a curse?

por Ahring, Philip Kiær, Liao, Vivian Wan Yu, Balle, Thomas
Publicado 2018

A Unified Model of the GABA(A) Receptor Comprising Agonist and Benzodiazepine Binding Sites

por Bergmann, Rikke, Kongsbak, Kristine, Sørensen, Pernille Louise, Sander, Tommy, Balle, Thomas
Publicado 2013

Molecular Recognition of the Neurotransmitter Acetylcholine by an Acetylcholine Binding Protein Reveals Determinants of Binding to Nicotinic Acetylcholine Receptors

por Olsen, Jeppe A., Balle, Thomas, Gajhede, Michael, Ahring, Philip K., Kastrup, Jette S.
Publicado 2014

Innate Immunity and Inflammation Post-Stroke: An α7-Nicotinic Agonist Perspective

por Neumann, Silke, Shields, Nicholas J., Balle, Thomas, Chebib, Mary, Clarkson, Andrew N.
Publicado 2015

Structure-Based Discovery of Dual-Target Hits for Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptors: In Silico Studies and In Vitro Confirmation

por Oddsson, Sebastian, Kowal, Natalia M., Ahring, Philip K., Olafsdottir, Elin S., Balle, Thomas
Publicado 2020

Binding and Dynamics Demonstrate the Destabilization of Ligand Binding for the S688Y Mutation in the NMDA Receptor GluN1 Subunit

por Chen, Jake Zheng, Church, William Bret, Bastard, Karine, Duff, Anthony P., Balle, Thomas
Publicado 2023

Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHβE Suggests a Unique Mode of Antagonism

por Shahsavar, Azadeh, Kastrup, Jette S., Nielsen, Elsebet Ø., Kristensen, Jesper L., Gajhede, Michael, Balle, Thomas
Publicado 2012

Novel Approach for the Search for Chemical Scaffolds with Activity at Both Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptor: A Perspective on Scaffolds with Dual Ac...

por Kowal, Natalia M., Indurthi, Dinesh C., Ahring, Philip K., Chebib, Mary, Olafsdottir, Elin S., Balle, Thomas
Publicado 2019

Combination of High-Resolution Structures for the B Cell Receptor and Co-Receptors Provides an Understanding of Their Interactions with Therapeutic Antibodies

por Bhattacharyya, Puja, Christopherson, Richard I., Skarratt, Kristen K., Chen, Jake Z., Balle, Thomas, Fuller, Stephen J.
Publicado 2023

Ligand Binding at the α4-α4 Agonist-Binding Site of the α4β2 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State

por Indurthi, Dinesh C., Lewis, Trevor M., Ahring, Philip K., Balle, Thomas, Chebib, Mary, Absalom, Nathan L.
Publicado 2016

Quantitative Toxicity Prediction via Meta Ensembling of Multitask Deep Learning Models

por Karim, Abdul, Riahi, Vahid, Mishra, Avinash, Newton, M. A. Hakim, Dehzangi, Abdollah, Balle, Thomas, Sattar, Abdul
Publicado 2021

Concatenated γ-aminobutyric acid type A receptors revisited: Finding order in chaos

por Liao, Vivian Wan Yu, Chua, Han Chow, Kowal, Natalia Magdalena, Chebib, Mary, Balle, Thomas, Ahring, Philip Kiær
Publicado 2019

Alternatively Spliced Isoforms of the P2X7 Receptor: Structure, Function and Disease Associations

por De Salis, Sophie K. F., Li, Lanxin, Chen, Zheng, Lam, Kam Wa, Skarratt, Kristen K., Balle, Thomas, Fuller, Stephen J.
Publicado 2022