RAS MAPK inhibitors deregulation in leukemia

por Pasmant, Eric, Vidaud, Dominique, Ballerini, Paola
Publicado 2015

Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

por Clappier, Emmanuelle, Gerby, Bastien, Sigaux, François, Delord, Marc, Touzri, Farah, Hernandez, Lucie, Ballerini, Paola, Baruchel, André, Pflumio, Françoise, Soulier, Jean
Publicado 2011

Germline RUNX1 variants in paediatric patients in a French specialised centre

por Liu, Cécile, Ballerini, Paola, Nguyen, Guillaume, Mincheva, Zoia, Copin, Bruno, Bouslama, Boutheina, Leverger, Guy, Petit, Arnaud, Favier, Rémi, Lapillonne, Hélène, Boutroux, Hélène
Publicado 2022

NKX3.1 is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia

por Kusy, Sophie, Gerby, Bastien, Goardon, Nicolas, Gault, Nathalie, Ferri, Federica, Gérard, Delphine, Armstrong, Florence, Ballerini, Paola, Cayuela, Jean-Michel, Baruchel, André, Pflumio, Françoise, Roméo, Paul-Henri
Publicado 2010

Speed of leukemia development and genetic diversity in xenograft models of T cell acute lymphoblastic leukemia

por Poglio, Sandrine, Lewandowski, Daniel, Calvo, Julien, Caye, Aurélie, Gros, Audrey, Laharanne, Elodie, Leblanc, Thierry, Landman-Parker, Judith, Baruchel, André, Soulier, Jean, Ballerini, Paola, Clappier, Emmanuelle, Pflumio, Françoise
Publicado 2016

TIM3, a human acute myeloid leukemia stem cell marker, does not enrich for leukemia-initiating stem cells in B-cell acute lymphoblastic leukemia

por Bueno, Clara, Martínez, Alba, Romecin, Paola Alejandra, Zanetti, Samanta Romina, Tirtakusuma, Ricky, Genesca, Eulalia, Camós, Mireia, Ramírez-Orellana, Manuel, Anguita, Eduardo, Ballerini, Paola, Locatelli, Franco, Fuster, José Luis, Menéndez, Pablo
Publicado 2023

HSP90 inhibitor NVP-BEP800 affects stability of SRC kinases and growth of T-cell and B-cell acute lymphoblastic leukemias

por Mshaik, Rony, Simonet, John, Georgievski, Aleksandra, Jamal, Layla, Bechoua, Shaliha, Ballerini, Paola, Bellaye, Pierre-Simon, Mlamla, Zandile, Pais de Barros, Jean-Paul, Geissler, Audrey, Francin, Pierre-Jean, Girodon, François, Garrido, Carmen, Quéré, Ronan
Publicado 2021

Prognostic impact of RUNX1 mutations and deletions in pediatric acute myeloid leukemia: results from the French ELAM02 study group

por Lew-Derivry, Lucille, Marceau-Renaut, Alice, Fenwarth, Laurène, Cuccuini, Wendy, Ballerini, Paola, Ferreboeuf, Maxime, Guilmatre, Audrey, Petit, Arnaud, Gandemer, Virginie, Rialland, Fanny, Schneider, Pascale, Michel, Gérard, Bertrand, Yves, Baruchel, Andre, Preudhomme, Claude, Leverger, Guy, Lapillonne, Hélène
Publicado 2023

NG2 antigen is a therapeutic target for MLL-rearranged B-cell acute lymphoblastic leukemia

por Lopez-Millan, Belen, Sanchéz-Martínez, Diego, Roca-Ho, Heleia, Gutiérrez-Agüera, Francisco, Molina, Oscar, Diaz de la Guardia, Rafael, Torres-Ruiz, Raúl, Fuster, Jose Luís, Ballerini, Paola, Suessbier, Ute, Nombela-Arrieta, Cesar, Bueno, Clara, Menéndez, Pablo
Publicado 2019

Efficient elimination of primary B-ALL cells in vitro and in vivo using a novel 4-1BB-based CAR targeting a membrane-distal CD22 epitope

por Velasco-Hernandez, Talia, Zanetti, Samanta Romina, Roca-Ho, Heleia, Gutierrez-Aguera, Francisco, Petazzi, Paolo, Sánchez-Martínez, Diego, Molina, Oscar, Baroni, Matteo Libero, Fuster, Jose Luis, Ballerini, Paola, Bueno, Clara, Fernandez-Fuentes, Narcis, Engel, Pablo, Menendez, Pablo
Publicado 2020

Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysis

por Agraz-Doblas, Antonio, Bueno, Clara, Bashford-Rogers, Rachael, Roy, Anindita, Schneider, Pauline, Bardini, Michela, Ballerini, Paola, Cazzaniga, Gianni, Moreno, Thaidy, Revilla, Carlos, Gut, Marta, Valsecchi, Maria G., Roberts, Irene, Pieters, Rob, De Lorenzo, Paola, Varela, Ignacio, Menendez, Pablo, Stam, Ronald W.
Publicado 2019

Germline RUNX1 Intragenic Deletion: Implications for Accurate Diagnosis of FPD/AML

por Duployez, Nicolas, Martin, Jean-Edouard, Khalife-Hachem, Sabine, Benkhelil, Ryane, Saada, Véronique, Marzac, Christophe, Auger, Nathalie, Marceau-Renaut, Alice, Favier, Rémi, Ballerini, Paola, Caron, Olivier, Baruchel, André, de Botton, Stéphane, Preudhomme, Claude, Micol, Jean-Baptiste, Raslova, Hana, Antony-Debré, Iléana
Publicado 2019

Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progression

por Uzan, Benjamin, Poglio, Sandrine, Gerby, Bastien, Wu, Ching-Lien, Gross, Julia, Armstrong, Florence, Calvo, Julien, Cahu, Xavier, Deswarte, Caroline, Dumont, Florent, Passaro, Diana, Besnard-Guérin, Corinne, Leblanc, Thierry, Baruchel, André, Landman-Parker, Judith, Ballerini, Paola, Baud, Véronique, Ghysdael, Jacques, Baleydier, Frédéric, Porteu, Francoise, Pflumio, Francoise
Publicado 2014

Haematological spectrum and genotype-phenotype correlations in nine unrelated families with RUNX1 mutations from the French network on inherited platelet disorders

por Latger-Cannard, Veronique, Philippe, Christophe, Bouquet, Alexandre, Baccini, Veronique, Alessi, Marie-Christine, Ankri, Annick, Bauters, Anne, Bayart, Sophie, Cornillet-Lefebvre, Pascale, Daliphard, Sylvie, Mozziconacci, Marie-Joelle, Renneville, Aline, Ballerini, Paola, Leverger, Guy, Sobol, Hagay, Jonveaux, Philippe, Preudhomme, Claude, Nurden, Paquita, Lecompte, Thomas, Favier, Remi
Publicado 2016

Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture

por Stritt, Simon, Nurden, Paquita, Favier, Remi, Favier, Marie, Ferioli, Silvia, Gotru, Sanjeev K., van Eeuwijk, Judith M M., Schulze, Harald, Nurden, Alan T., Lambert, Michele P., Turro, Ernest, Burger-Stritt, Stephanie, Matsushita, Masayuki, Mittermeier, Lorenz, Ballerini, Paola, Zierler, Susanna, Laffan, Michael A., Chubanov, Vladimir, Gudermann, Thomas, Nieswandt, Bernhard, Braun, Attila
Publicado 2016

A novel and efficient tandem CD19- and CD22-directed CAR for B cell ALL

por Zanetti, Samanta Romina, Velasco-Hernandez, Talia, Gutierrez-Agüera, Francisco, Díaz, Víctor M., Romecín, Paola Alejandra, Roca-Ho, Heleia, Sánchez-Martínez, Diego, Tirado, Néstor, Baroni, Matteo Libero, Petazzi, Paolo, Torres-Ruiz, Raúl, Molina, Oscar, Bataller, Alex, Fuster, José Luis, Ballerini, Paola, Juan, Manel, Jeremias, Irmela, Bueno, Clara, Menéndez, Pablo
Publicado 2022

Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high‐hyperdiploid B‐cell acute lymphoblastic leukemia

por Ramos‐Muntada, Mireia, Trincado, Juan L., Blanco, Joan, Bueno, Clara, Rodríguez‐Cortez, Virginia C., Bataller, Alex, López‐Millán, Belén, Schwab, Claire, Ortega, Margarita, Velasco, Pablo, Blanco, Maria L., Nomdedeu, Josep, Ramírez‐Orellana, Manuel, Minguela, Alfredo, Fuster, Jose L., Cuatrecasas, Esther, Camós, Mireia, Ballerini, Paola, Escherich, Gabriele, Boer, Judith, DenBoer, Monique, Hernández‐Rivas, Jesús M., Calasanz, Maria J., Cazzaniga, Giovanni, Harrison, Christine J., Menéndez, Pablo, Molina, Oscar
Publicado 2022

Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models

por Thiollier, Clarisse, Lopez, Cécile K., Gerby, Bastien, Ignacimouttou, Cathy, Poglio, Sandrine, Duffourd, Yannis, Guégan, Justine, Rivera-Munoz, Paola, Bluteau, Olivier, Mabialah, Vinciane, Diop, M’Boyba, Wen, Qiang, Petit, Arnaud, Bauchet, Anne-Laure, Reinhardt, Dirk, Bornhauser, Beat, Gautheret, Daniel, Lecluse, Yann, Landman-Parker, Judith, Radford, Isabelle, Vainchenker, William, Dastugue, Nicole, de Botton, Stéphane, Dessen, Philippe, Bourquin, Jean-Pierre, Crispino, John D., Ballerini, Paola, Bernard, Olivier A., Pflumio, Françoise, Mercher, Thomas
Publicado 2012