Discovery of C—C bond-forming and bond-breaking radical enzymes: enabling transformations for metabolic engineering

por Fu, Beverly, Balskus, Emily P
Publicado 2020

A diversified, widespread microbial gene cluster encodes homologs of methyltransferases involved in methanogenesis

por Kountz, Duncan J., Balskus, Emily P.
Publicado 2023

Shedding light on sunscreen biosynthesis in zebrafish

por Brotherton, Carolyn A, Balskus, Emily P
Publicado 2015

Metabolic functions of the human gut microbiota: the role of metalloenzymes

por Rajakovich, Lauren J., Balskus *, Emily P.
Publicado 2018

Deciphering Human Microbiota–Host Chemical Interactions

por Silpe, Justin E., Balskus, Emily P.
Publicado 2020

Leveraging Microbial Genomes and Genomic Context for Chemical Discovery

por Kountz, Duncan J., Balskus, Emily P.
Publicado 2021

Chemical transformation of xenobiotics by the human gut microbiota

por Koppel, Nitzan, Rekdal, Vayu Maini, Balskus, Emily P.
Publicado 2018

Announcement of 2019 Keystone Symposia Conference: “Microbiome: Chemical Mechanisms and Biological Consequences”

por Balskus, Emily P., Turnbaugh, Peter J., Wolan, Dennis W.
Publicado 2018

Anaerobic 4-hydroxyproline utilization: Discovery of a new glycyl radical enzyme in the human gut microbiome uncovers a widespread microbial metabolic activity

por Huang, Yolanda Y., Martínez-del Campo, Ana, Balskus, Emily P.
Publicado 2018

Elucidation of an anaerobic pathway for metabolism of l-carnitine–derived γ-butyrobetaine to trimethylamine in human gut bacteria

por Rajakovich, Lauren J., Fu, Beverly, Bollenbach, Maud, Balskus, Emily P.
Publicado 2021

Mechanistic insight into digoxin inactivation by Eggerthella lenta augments our understanding of its pharmacokinetics

por Haiser, Henry J, Seim, Kristen L, Balskus, Emily P, Turnbaugh, Peter J
Publicado 2014

An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin

por Ng, Tai L., Rohac, Roman, Mitchell, Andrew, Boal, Amie K., Balskus, Emily P.
Publicado 2019

Discovery and characterization of a prevalent human gut bacterial enzyme sufficient for the inactivation of a family of plant toxins

por Koppel, Nitzan, Bisanz, Jordan E, Pandelia, Maria-Eirini, Turnbaugh, Peter J, Balskus, Emily P
Publicado 2018

A glycyl radical enzyme enables hydrogen sulfide production by the human intestinal bacterium Bilophila wadsworthia

por Peck, Spencer C., Denger, Karin, Burrichter, Anna, Irwin, Stephania M., Balskus, Emily P., Schleheck, David
Publicado 2019

Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism

por Rekdal, Vayu Maini, Bess, Elizabeth N., Bisanz, Jordan E., Turnbaugh, Peter J., Balskus, Emily P.
Publicado 2019

The bacterial toxin colibactin triggers prophage induction

por Silpe, Justin E., Wong, Joel W. H., Owen, Siân V., Baym, Michael, Balskus, Emily P.
Publicado 2022

Mechanistic Studies of a Skatole-Forming Glycyl Radical Enzyme Suggest Reaction Initiation via Hydrogen Atom Transfer

por Fu, Beverly, Nazemi, Azadeh, Levin, Benjamin J., Yang, Zhongyue, Kulik, Heather J., Balskus, Emily P.
Publicado 2022

Distribution and diversity of dimetal-carboxylate halogenases in cyanobacteria

por Eusebio, Nadia, Rego, Adriana, Glasser, Nathaniel R., Castelo-Branco, Raquel, Balskus, Emily P., Leão, Pedro N.
Publicado 2021

Biosynthesis of the Unusual Carbon Skeleton of Nocuolin A

por Martins, Teresa P., Glasser, Nathaniel R., Kountz, Duncan J., Oliveira, Paulo, Balskus, Emily P., Leão, Pedro N.
Publicado 2022

Structural basis of colibactin activation by the ClbP peptidase

por Velilla, José A., Volpe, Matthew R., Kenney, Grace E., Walsh, Richard M., Balskus, Emily P., Gaudet, Rachelle
Publicado 2022