P007. Inhibition of monoacylglycerol lipase activity modulates the activation of brain structures relevant for migraine pathogenesis

por Greco, Rosaria, Bandiera, Tiziano, Mangione, Antonina S, Demartini, Chiara, Nappi, Giuseppe, Sandrini, Giorgio, Piomelli, Daniele, Tassorelli, Cristina
Publicado 2015

Thermal stabilization of the deglycating enzyme Amadoriase I by rational design

por Rigoldi, Federica, Donini, Stefano, Giacomina, Francesca, Sorana, Federico, Redaelli, Alberto, Bandiera, Tiziano, Parisini, Emilio, Gautieri, Alfonso
Publicado 2018

Distinctive lipid signatures of bronchial epithelial cells associated with cystic fibrosis drugs, including Trikafta

por Liessi, Nara, Pesce, Emanuela, Braccia, Clarissa, Bertozzi, Sine Mandrup, Giraudo, Alessandro, Bandiera, Tiziano, Pedemonte, Nicoletta, Armirotti, Andrea
Publicado 2020

Physiological adaptations affecting drug pharmacokinetics in space: what do we really know? A critical review of the literature

por Dello Russo, Cinzia, Bandiera, Tiziano, Monici, Monica, Surdo, Leonardo, Yip, Vincent Lai Ming, Wotring, Virginia, Morbidelli, Lucia
Publicado 2022

Small Molecules Targeting DNA Polymerase Theta (POLθ) as Promising Synthetic Lethal Agents for Precision Cancer Therapy

por Pismataro, Maria Chiara, Astolfi, Andrea, Barreca, Maria Letizia, Pacetti, Martina, Schenone, Silvia, Bandiera, Tiziano, Carbone, Anna, Massari, Serena
Publicado 2023

A European regulatory perspective on cystic fibrosis: current treatments, trends in drug development and translational challenges for CFTR modulators

por Ponzano, Stefano, Nigrelli, Giulia, Fregonese, Laura, Eichler, Irmgard, Bertozzi, Fabio, Bandiera, Tiziano, Galietta, Luis J.V., Papaluca, Marisa
Publicado 2018

Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity

por Realini, Natalia, Solorzano, Carlos, Pagliuca, Chiara, Pizzirani, Daniela, Armirotti, Andrea, Luciani, Rosaria, Costi, Maria Paola, Bandiera, Tiziano, Piomelli, Daniele
Publicado 2013

Pharmacological potentiators of the calcium signaling cascade identified by high-throughput screening

por Genovese, Michele, Guidone, Daniela, Buccirossi, Martina, Borrelli, Anna, Rodriguez-Gimeno, Alejandra, Bertozzi, Fabio, Bandiera, Tiziano, Galietta, Luis J V
Publicado 2022

Identification of Novel GSK-3β Hits Using Competitive Biophysical Assays

por Balboni, Beatrice, Tripathi, Shailesh Kumar, Veronesi, Marina, Russo, Debora, Penna, Ilaria, Giabbai, Barbara, Bandiera, Tiziano, Storici, Paola, Girotto, Stefania, Cavalli, Andrea
Publicado 2022

A catalytically silent FAAH-1 variant drives anandamide transport in neurons

por Fu, Jin, Bottegoni, Giovanni, Sasso, Oscar, Bertorelli, Rosalia, Rocchia, Walter, Masetti, Matteo, Guijarro, Ana, Lodola, Alessio, Armirotti, Andrea, Garau, Gianpiero, Bandiera, Tiziano, Reggiani, Angelo, Mor, Marco, Cavalli, Andrea, Piomelli, Daniele
Publicado 2011

CFTR Rescue by Lumacaftor (VX-809) Induces an Extensive Reorganization of Mitochondria in the Cystic Fibrosis Bronchial Epithelium

por Braccia, Clarissa, Christopher, Josie A., Crook, Oliver M., Breckels, Lisa M., Queiroz, Rayner M. L., Liessi, Nara, Tomati, Valeria, Capurro, Valeria, Bandiera, Tiziano, Baldassari, Simona, Pedemonte, Nicoletta, Lilley, Kathryn S., Armirotti, Andrea
Publicado 2022

First Characterization of Human Amniotic Fluid Stem Cell Extracellular Vesicles as a Powerful Paracrine Tool Endowed with Regenerative Potential

por Balbi, Carolina, Piccoli, Martina, Barile, Lucio, Papait, Andrea, Armirotti, Andrea, Principi, Elisa, Reverberi, Daniele, Pascucci, Luisa, Becherini, Pamela, Varesio, Luigi, Mogni, Massimo, Coviello, Domenico, Bandiera, Tiziano, Pozzobon, Michela, Cancedda, Ranieri, Bollini, Sveva
Publicado 2017

Discovery of a picomolar potency pharmacological corrector of the mutant CFTR chloride channel

por Pedemonte, Nicoletta, Bertozzi, Fabio, Caci, Emanuela, Sorana, Federico, Di Fruscia, Paolo, Tomati, Valeria, Ferrera, Loretta, Rodríguez-Gimeno, Alejandra, Berti, Francesco, Pesce, Emanuela, Sondo, Elvira, Gianotti, Ambra, Scudieri, Paolo, Bandiera, Tiziano, Galietta, Luis J. V.
Publicado 2020

Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel

por Renda, Mario, Barreca, Marilia, Borrelli, Anna, Spanò, Virginia, Montalbano, Alessandra, Raimondi, Maria Valeria, Bivacqua, Roberta, Musante, Ilaria, Scudieri, Paolo, Guidone, Daniela, Buccirossi, Martina, Genovese, Michele, Venturini, Arianna, Bandiera, Tiziano, Barraja, Paola, Galietta, Luis J. V.
Publicado 2023

Partial Rescue of F508del-CFTR Stability and Trafficking Defects by Double Corrector Treatment

por Capurro, Valeria, Tomati, Valeria, Sondo, Elvira, Renda, Mario, Borrelli, Anna, Pastorino, Cristina, Guidone, Daniela, Venturini, Arianna, Giraudo, Alessandro, Mandrup Bertozzi, Sine, Musante, Ilaria, Bertozzi, Fabio, Bandiera, Tiziano, Zara, Federico, Galietta, Luis J. V., Pedemonte, Nicoletta
Publicado 2021

The L467F-F508del Complex Allele Hampers Pharmacological Rescue of Mutant CFTR by Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis Patients: The Value of the Ex Vivo Nasal Epith...

por Sondo, Elvira, Cresta, Federico, Pastorino, Cristina, Tomati, Valeria, Capurro, Valeria, Pesce, Emanuela, Lena, Mariateresa, Iacomino, Michele, Baffico, Ave Maria, Coviello, Domenico, Bandiera, Tiziano, Zara, Federico, Galietta, Luis J. V., Bocciardi, Renata, Castellani, Carlo, Pedemonte, Nicoletta
Publicado 2022

Identification, Structure–Activity Relationship, and Biological Characterization of 2,3,4,5-Tetrahydro-1H-pyrido[4,3-b]indoles as a Novel Class of CFTR Potentiators

por Brindani, Nicoletta, Gianotti, Ambra, Giovani, Simone, Giacomina, Francesca, Di Fruscia, Paolo, Sorana, Federico, Bertozzi, Sine Mandrup, Ottonello, Giuliana, Goldoni, Luca, Penna, Ilaria, Russo, Debora, Summa, Maria, Bertorelli, Rosalia, Ferrera, Loretta, Pesce, Emanuela, Sondo, Elvira, Galietta, Luis J. V., Bandiera, Tiziano, Pedemonte, Nicoletta, Bertozzi, Fabio
Publicado 2020

Discovery and SAR Evolution of Pyrazole Azabicyclo[3.2.1]octane Sulfonamides as a Novel Class of Non-Covalent N-Acylethanolamine-Hydrolyzing Acid Amidase (NAAA) Inhibitors for Oral...

por Di Fruscia, Paolo, Carbone, Anna, Bottegoni, Giovanni, Berti, Francesco, Giacomina, Francesca, Ponzano, Stefano, Pagliuca, Chiara, Fiasella, Annalisa, Pizzirani, Daniela, Ortega, Jose Antonio, Nuzzi, Andrea, Tarozzo, Glauco, Mengatto, Luisa, Giampà, Roberta, Penna, Ilaria, Russo, Debora, Romeo, Elisa, Summa, Maria, Bertorelli, Rosalia, Armirotti, Andrea, Bertozzi, Sine Mandrup, Reggiani, Angelo, Bandiera, Tiziano, Bertozzi, Fabio
Publicado 2021