Preclinical In Vivo Modeling of Pediatric Sarcoma—Promises and Limitations

por Imle, Roland, Kommoss, Felix K. F., Banito, Ana
Publicado 2021

Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence

por Aarts, Marieke, Georgilis, Athena, Beniazza, Meryam, Beolchi, Patrizia, Banito, Ana, Carroll, Thomas, Kulisic, Marizela, Kaemena, Daniel F., Dharmalingam, Gopuraja, Martin, Nadine, Reik, Wolf, Zuber, Johannes, Kaji, Keisuke, Chandra, Tamir, Gil, Jesús
Publicado 2017

Aberrant gene activation in synovial sarcoma relies on SSX specificity and increased PRC1.1 stability

por Benabdallah, Nezha S., Dalal, Vineet, Scott, R. Wilder, Marcous, Fady, Sotiriou, Afroditi, Kommoss, Felix K. F., Pejkovska, Anastasija, Gaspar, Ludmila, Wagner, Lena, Sánchez-Rivera, Francisco J., Ta, Monica, Thornton, Shelby, Nielsen, Torsten O., Underhill, T. Michael, Banito, Ana
Publicado 2023

MODL-07. DNA methylation-based biobank of murine models for pediatric tumors

por Zheng, Tuyu, Sill, Martin, Imle, Roland, Shiraishi, Ryo, Wang, Wanchen, Morcavallo, Alaide, Chesler, Louis, Kawauchi, Daisuke, Ayrault, Olivier, Pavlo, Lutsik, Pfister, Stefan M, Kutscher, Lena M, Banito, Ana, Jones, David W, Pajtler, Kristian W, Zuckermann, Marc
Publicado 2022

SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer

por Tordella, Luca, Khan, Sadaf, Hohmeyer, Anja, Banito, Ana, Klotz, Sabrina, Raguz, Selina, Martin, Nadine, Dhamarlingam, Gopuraja, Carroll, Thomas, González Meljem, José Mario, Deswal, Sumit, Martínez-Barbera, Juan Pedro, García-Escudero, Ramón, Zuber, Johannes, Zender, Lars, Gil, Jesús
Publicado 2016

Endometrial stromal sarcomas with BCOR‐rearrangement harbor MDM2 amplifications

por Kommoss, Felix KF, Chang, Kenneth TE, Stichel, Damian, Banito, Ana, Jones, David TW, Heilig, Christoph E, Fröhling, Stefan, Sahm, Felix, Stenzinger, Albrecht, Hartmann, Wolfgang, Mechtersheimer, Gunhild, Sinn, Hans‐Peter, Schmidt, Dietmar, Kommoss, Friedrich, von Deimling, Andreas, Koelsche, Christian
Publicado 2020

A Role for SMARCB1 in Synovial Sarcomagenesis Reveals That SS18–SSX Induces Canonical BAF Destruction

por Li, Jinxiu, Mulvihill, Timothy S., Li, Li, Barrott, Jared J., Nelson, Mary L., Wagner, Lena, Lock, Ian C., Pozner, Amir, Lambert, Sydney Lynn, Ozenberger, Benjamin B., Ward, Michael B., Grossmann, Allie H., Liu, Ting, Banito, Ana, Cairns, Bradley R., Jones, Kevin B.
Publicado 2021

MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer

por Zhu, Changyu, Soto-Feliciano, Yadira M, Morris, John P, Huang, Chun-Hao, Koche, Richard P, Ho, Yu-jui, Banito, Ana, Chen, Chun-Wei, Shroff, Aditya, Tian, Sha, Livshits, Geulah, Chen, Chi-Chao, Fennell, Myles, Armstrong, Scott A, Allis, C David, Tschaharganeh, Darjus F, Lowe, Scott W
Publicado 2023

Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer

por Revia, Steffie, Seretny, Agnieszka, Wendler, Lena, Banito, Ana, Eckert, Christoph, Breuer, Kersten, Mayakonda, Anand, Lutsik, Pavlo, Evert, Matthias, Ribback, Silvia, Gallage, Suchira, Chikh Bakri, Ismaiel, Breuhahn, Kai, Schirmacher, Peter, Heinrich, Stefan, Gaida, Matthias M, Heikenwälder, Mathias, Calvisi, Diego F, Plass, Christoph, Lowe, Scott W, Tschaharganeh, Darjus F
Publicado 2022

MicroRNA Regulation of Cbx7 Mediates a Switch of Polycomb Orthologs during ESC Differentiation

por O'Loghlen, Ana, Muñoz-Cabello, Ana M., Gaspar-Maia, Alexandre, Wu, Hsan-Au, Banito, Ana, Kunowska, Natalia, Racek, Tomas, Pemberton, Helen N., Beolchi, Patrizia, Lavial, Fabrice, Masui, Osamu, Vermeulen, Michiel, Carroll, Thomas, Graumann, Johannes, Heard, Edith, Dillon, Niall, Azuara, Veronique, Snijders, Ambrosius P., Peters, Gordon, Bernstein, Emily, Gil, Jesus
Publicado 2012

A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets

por Li, Xiang, Huang, Chun-Hao, Sánchez-Rivera, Francisco J., Kennedy, Margaret C., Tschaharganeh, Darjus F., Morris, John P., Montinaro, Antonella, O'Rourke, Kevin P., Banito, Ana, Wilkinson, John E., Chen, Chi-Chao, Ho, Yu-Jui, Dow, Lukas E., Tian, Sha, Luan, Wei, de Stanchina, Elisa, Zhang, Tinghu, Gray, Nathanael S., Walczak, Henning, Lowe, Scott W.
Publicado 2022

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

por Acosta, Juan Carlos, Banito, Ana, Wuestefeld, Torsten, Georgilis, Athena, Janich, Peggy, Morton, Jennifer P, Athineos, Dimitris, Kang, Tae-Won, Lasitschka, Felix, Andrulis, Mindaugas, Pascual, Gloria, Morris, Kelly J., Khan, Sadaf, Jin, Hong, Dharmalingam, Gopuraja, Snijders, Ambrosius P., Carroll, Thomas, Capper, David, Pritchard, Catrin, Inman, Gareth J., Longerich, Thomas, Sansom, Owen J., Benitah, Salvador Aznar, Zender, Lars, Gil, Jesús
Publicado 2013

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

por Herranz, Nicolás, Gallage, Suchira, Mellone, Massimiliano, Wuestefeld, Torsten, Klotz, Sabrina, Hanley, Christopher J., Raguz, Selina, Acosta, Juan Carlos, Innes, Andrew J, Banito, Ana, Georgilis, Athena, Montoya, Alex, Wolter, Katharina, Dharmalingam, Gopuraja, Faull, Peter, Carroll, Thomas, Martínez-Barbera, Juan Pedro, Cutillas, Pedro, Reisinger, Florian, Heikenwalder, Mathias, Miller, Richard A., Withers, Dominic, Zender, Lars, Thomas, Gareth J., Gil, Jesús
Publicado 2015

Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer

por Li, Jing, Ohmura, Shunya, Marchetto, Aruna, Orth, Martin F., Imle, Roland, Dallmayer, Marlene, Musa, Julian, Knott, Maximilian M. L., Hölting, Tilman L. B., Stein, Stefanie, Funk, Cornelius M., Sastre, Ana, Alonso, Javier, Bestvater, Felix, Kasan, Merve, Romero-Pérez, Laura, Hartmann, Wolfgang, Ranft, Andreas, Banito, Ana, Dirksen, Uta, Kirchner, Thomas, Cidre-Aranaz, Florencia, Grünewald, Thomas G. P.
Publicado 2021

Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models

por Gatzweiler, Charlotte, Ridinger, Johannes, Herter, Sonja, Gerloff, Xenia F., ElHarouni, Dina, Berker, Yannick, Imle, Roland, Schmitt, Lukas, Kreth, Sina, Stainczyk, Sabine, Ayhan, Simay, Najafi, Sara, Krunic, Damir, Frese, Karen, Meder, Benjamin, Reuss, David, Fiesel, Petra, Schramm, Kathrin, Blattner-Johnson, Mirjam, Jones, David T. W., Banito, Ana, Westermann, Frank, Oppermann, Sina, Milde, Till, Peterziel, Heike, Witt, Olaf, Oehme, Ina
Publicado 2022

Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma

por Cidre-Aranaz, Florencia, Li, Jing, Hölting, Tilman L. B., Orth, Martin F., Imle, Roland, Kutschmann, Stefanie, Ammirati, Giulia, Ceranski, Katharina, Carreño-Gonzalez, Martha Julia, Kasan, Merve, Marchetto, Aruna, Funk, Cornelius M., Bestvater, Felix, Bersini, Simone, Arrigoni, Chiara, Moretti, Matteo, Thiel, Uwe, Baumhoer, Daniel, Sahm, Felix, Pfister, Stefan M., Hartmann, Wolfgang, Dirksen, Uta, Romero-Pérez, Laura, Banito, Ana, Ohmura, Shunya, Musa, Julian, Kirchner, Thomas, Knott, Maximilian M. L., Grünewald, Thomas G. P.
Publicado 2022

Sarcoma treatment in the era of molecular medicine

por Grünewald, Thomas GP, Alonso, Marta, Avnet, Sofia, Banito, Ana, Burdach, Stefan, Cidre‐Aranaz, Florencia, Di Pompo, Gemma, Distel, Martin, Dorado‐Garcia, Heathcliff, Garcia‐Castro, Javier, González‐González, Laura, Grigoriadis, Agamemnon E, Kasan, Merve, Koelsche, Christian, Krumbholz, Manuela, Lecanda, Fernando, Lemma, Silvia, Longo, Dario L, Madrigal‐Esquivel, Claudia, Morales‐Molina, Álvaro, Musa, Julian, Ohmura, Shunya, Ory, Benjamin, Pereira‐Silva, Miguel, Perut, Francesca, Rodriguez, Rene, Seeling, Carolin, Al Shaaili, Nada, Shaabani, Shabnam, Shiavone, Kristina, Sinha, Snehadri, Tomazou, Eleni M, Trautmann, Marcel, Vela, Maria, Versleijen‐Jonkers, Yvonne MH, Visgauss, Julia, Zalacain, Marta, Schober, Sebastian J, Lissat, Andrej, English, William R, Baldini, Nicola, Heymann, Dominique
Publicado 2020