Dynamic effects of genetic variation on gene expression revealed following hypoxic stress in cardiomyocytes

por Ward, Michelle C, Banovich, Nicholas E, Sarkar, Abhishek, Stephens, Matthew, Gilad, Yoav
Publicado 2021

The case for increasing diversity in tissue-based functional genomics datasets to understand human disease susceptibility

por Long, Erping, García-Closas, Montserrat, Chanock, Stephen J., Camargo, M. Constanza, Banovich, Nicholas E., Choi, Jiyeon
Publicado 2022

Genetic Variation, Not Cell Type of Origin, Underlies the Majority of Identifiable Regulatory Differences in iPSCs

por Burrows, Courtney K., Banovich, Nicholas E., Pavlovic, Bryan J., Patterson, Kristen, Gallego Romero, Irene, Pritchard, Jonathan K., Gilad, Yoav
Publicado 2016

Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels

por Banovich, Nicholas E., Lan, Xun, McVicker, Graham, van de Geijn, Bryce, Degner, Jacob F., Blischak, John D., Roux, Julien, Pritchard, Jonathan K., Gilad, Yoav
Publicado 2014

A comparison of gene expression and DNA methylation patterns across tissues and species

por Blake, Lauren E., Roux, Julien, Hernando-Herraez, Irene, Banovich, Nicholas E., Perez, Raquel Garcia, Hsiao, Chiaowen Joyce, Eres, Ittai, Cuevas, Claudia, Marques-Bonet, Tomas, Gilad, Yoav
Publicado 2020

Genetic architecture of gene regulation in Indonesian populations identifies QTLs associated with global and local ancestries

por Natri, Heini M., Hudjashov, Georgi, Jacobs, Guy, Kusuma, Pradiptajati, Saag, Lauri, Darusallam, Chelzie Crenna, Metspalu, Mait, Sudoyo, Herawati, Cox, Murray P., Gallego Romero, Irene, Banovich, Nicholas E.
Publicado 2022

Genome-wide DNA methylation and gene expression patterns reflect genetic ancestry and environmental differences across the Indonesian archipelago

por Natri, Heini M., Bobowik, Katalina S., Kusuma, Pradiptajati, Crenna Darusallam, Chelzie, Jacobs, Guy S., Hudjashov, Georgi, Lansing, J. Stephen, Sudoyo, Herawati, Banovich, Nicholas E., Cox, Murray P., Gallego Romero, Irene
Publicado 2020

Impact of regulatory variation across human iPSCs and differentiated cells

por Banovich, Nicholas E., Li, Yang I., Raj, Anil, Ward, Michelle C., Greenside, Peyton, Calderon, Diego, Tung, Po Yuan, Burnett, Jonathan E., Myrthil, Marsha, Thomas, Samantha M., Burrows, Courtney K., Romero, Irene Gallego, Pavlovic, Bryan J., Kundaje, Anshul, Pritchard, Jonathan K., Gilad, Yoav
Publicado 2018

Age-determined expression of priming protease TMPRSS2 and localization of SARS-CoV-2 infection in the lung epithelium

por Schuler, Bryce A., Christian Habermann, A., Plosa, Erin J., Taylor, Chase J., Jetter, Christopher, Kapp, Meghan E., Benjamin, John T., Gulleman, Peter, Nichols, David S., Braunstein, Lior Z., Hackett, Alice, Koval, Michael, Guttentag, Susan H., Blackwell, Timothy S., Webber, Steven A., Banovich, Nicholas E., Kropski, Jonathan A., Sucre, Jennifer M. S.
Publicado 2020

A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics

por Gallego Romero, Irene, Pavlovic, Bryan J, Hernando-Herraez, Irene, Zhou, Xiang, Ward, Michelle C, Banovich, Nicholas E, Kagan, Courtney L, Burnett, Jonathan E, Huang, Constance H, Mitrano, Amy, Chavarria, Claudia I, Friedrich Ben-Nun, Inbar, Li, Yingchun, Sabatini, Karen, Leonardo, Trevor R, Parast, Mana, Marques-Bonet, Tomas, Laurent, Louise C, Loring, Jeanne F, Gilad, Yoav
Publicado 2015

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

por Bui, Linh T., Winters, Nichelle I., Chung, Mei-I, Joseph, Chitra, Gutierrez, Austin J., Habermann, Arun C., Adams, Taylor S., Schupp, Jonas C., Poli, Sergio, Peter, Lance M., Taylor, Chase J., Blackburn, Jessica B., Richmond, Bradley W., Nicholson, Andrew G., Rassl, Doris, Wallace, William A., Rosas, Ivan O., Jenkins, R. Gisli, Kaminski, Naftali, Kropski, Jonathan A., Banovich, Nicholas E.
Publicado 2021

Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity

por Bui, Linh T., Winters, Nichelle I., Chung, Mei-I, Joseph, Chitra, Gutierrez, Austin J., Habermann, Arun C., Adams, Taylor S., Schupp, Jonas C., Poli, Sergio, Peter, Lance M., Taylor, Chase J., Blackburn, Jessica B., Richmond, Bradley W., Nicholson, Andrew G., Rassl, Doris, Wallace, William A., Rosas, Ivan O., Jenkins, R. Gisli, Kaminski, Naftali, Kropski, Jonathan A., Banovich, Nicholas E.
Publicado 2021

Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis

por Habermann, Arun C., Gutierrez, Austin J., Bui, Linh T., Yahn, Stephanie L., Winters, Nichelle I., Calvi, Carla L., Peter, Lance, Chung, Mei-I, Taylor, Chase J., Jetter, Christopher, Raju, Latha, Roberson, Jamie, Ding, Guixiao, Wood, Lori, Sucre, Jennifer M. S., Richmond, Bradley W., Serezani, Ana P., McDonnell, Wyatt J., Mallal, Simon B., Bacchetta, Matthew J., Loyd, James E., Shaver, Ciara M., Ware, Lorraine B., Bremner, Ross, Walia, Rajat, Blackwell, Timothy S., Banovich, Nicholas E., Kropski, Jonathan A.
Publicado 2020

Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung

por Schupp, Jonas C., Adams, Taylor S., Cosme, Carlos, Raredon, Micha Sam Brickman, Yuan, Yifan, Omote, Norihito, Poli, Sergio, Chioccioli, Maurizio, Rose, Kadi-Ann, Manning, Edward P., Sauler, Maor, DeIuliis, Giuseppe, Ahangari, Farida, Neumark, Nir, Habermann, Arun C., Gutierrez, Austin J., Bui, Linh T., Lafyatis, Robert, Pierce, Richard W., Meyer, Kerstin B., Nawijn, Martijn C., Teichmann, Sarah A., Banovich, Nicholas E., Kropski, Jonathan A., Niklason, Laura E., Pe’er, Dana, Yan, Xiting, Homer, Robert J., Rosas, Ivan O., Kaminski, Naftali
Publicado 2021

PCSK6 and Survival in Idiopathic Pulmonary Fibrosis

por Oldham, Justin M., Allen, Richard J., Lorenzo-Salazar, Jose M., Molyneaux, Philip L., Ma, Shwu-Fan, Joseph, Chitra, Kim, John S., Guillen-Guio, Beatriz, Hernández-Beeftink, Tamara, Kropski, Jonathan A., Huang, Yong, Lee, Cathryn T., Adegunsoye, Ayodeji, Pugashetti, Janelle Vu, Linderholm, Angela L., Vo, Vivian, Strek, Mary E., Jou, Jonathan, Muñoz-Barrera, Adrian, Rubio-Rodriguez, Luis A., Hubbard, Richard, Hirani, Nik, Whyte, Moira K. B., Hart, Simon, Nicholson, Andrew G., Lancaster, Lisa, Parfrey, Helen, Rassl, Doris, Wallace, William, Valenzi, Eleanor, Zhang, Yingze, Mychaleckyj, Josyf, Stockwell, Amy, Kaminski, Naftali, Wolters, Paul J., Molina-Molina, Maria, Banovich, Nicholas E., Fahy, William A., Martinez, Fernando J., Hall, Ian P., Tobin, Martin D., Maher, Toby M., Blackwell, Timothy S., Yaspan, Brian L., Jenkins, R. Gisli, Flores, Carlos, Wain, Louise V., Noth, Imre
Publicado 2023

An integrated cell atlas of the lung in health and disease

por Sikkema, Lisa, Ramírez-Suástegui, Ciro, Strobl, Daniel C., Gillett, Tessa E., Zappia, Luke, Madissoon, Elo, Markov, Nikolay S., Zaragosi, Laure-Emmanuelle, Ji, Yuge, Ansari, Meshal, Arguel, Marie-Jeanne, Apperloo, Leonie, Banchero, Martin, Bécavin, Christophe, Berg, Marijn, Chichelnitskiy, Evgeny, Chung, Mei-i, Collin, Antoine, Gay, Aurore C. A., Gote-Schniering, Janine, Hooshiar Kashani, Baharak, Inecik, Kemal, Jain, Manu, Kapellos, Theodore S., Kole, Tessa M., Leroy, Sylvie, Mayr, Christoph H., Oliver, Amanda J., von Papen, Michael, Peter, Lance, Taylor, Chase J., Walzthoeni, Thomas, Xu, Chuan, Bui, Linh T., De Donno, Carlo, Dony, Leander, Faiz, Alen, Guo, Minzhe, Gutierrez, Austin J., Heumos, Lukas, Huang, Ni, Ibarra, Ignacio L., Jackson, Nathan D., Kadur Lakshminarasimha Murthy, Preetish, Lotfollahi, Mohammad, Tabib, Tracy, Talavera-López, Carlos, Travaglini, Kyle J., Wilbrey-Clark, Anna, Worlock, Kaylee B., Yoshida, Masahiro, van den Berge, Maarten, Bossé, Yohan, Desai, Tushar J., Eickelberg, Oliver, Kaminski, Naftali, Krasnow, Mark A., Lafyatis, Robert, Nikolic, Marko Z., Powell, Joseph E., Rajagopal, Jayaraj, Rojas, Mauricio, Rozenblatt-Rosen, Orit, Seibold, Max A., Sheppard, Dean, Shepherd, Douglas P., Sin, Don D., Timens, Wim, Tsankov, Alexander M., Whitsett, Jeffrey, Xu, Yan, Banovich, Nicholas E., Barbry, Pascal, Duong, Thu Elizabeth, Falk, Christine S., Meyer, Kerstin B., Kropski, Jonathan A., Pe’er, Dana, Schiller, Herbert B., Tata, Purushothama Rao, Schultze, Joachim L., Teichmann, Sara A., Misharin, Alexander V., Nawijn, Martijn C., Luecken, Malte D., Theis, Fabian J.
Publicado 2023