SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy

por Zhou, Li-Na, Xiong, Chaodong, Cheng, Yong-Jun, Song, Shan-Shan, Bao, Xu-Bin, Huan, Xia-Juan, Wang, Tong-Yan, Zhang, Ao, Miao, Ze-Hong, He, Jin-Xue
Publicado 2022

Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer

por Zhang, Ning, Tian, Yu-Nan, Zhou, Li-Na, Li, Meng-Zhu, Chen, Hua-Dong, Song, Shan-Shan, Huan, Xia-Juan, Bao, Xu-Bin, Zhang, Ao, Miao, Ze-Hong, He, Jin-Xue
Publicado 2021

Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance

por Wang, Li‐Min, Wang, Pingyuan, Chen, Xiao‐Min, Yang, Hui, Song, Shan‐Shan, Song, Zilan, Jia, Li, Chen, Hua‐Dong, Bao, Xu‐Bin, Guo, Ne, Huan, Xia‐Juan, Xi, Yong, Shen, Yan‐Yan, Yang, Xin‐Ying, Su, Yi, Sun, Yi‐Ming, Gao, Ying‐Lei, Chen, Yi, Ding, Jian, Lang, Jing‐Yu, Miao, Ze‐Hong, Zhang, Ao, He, Jin‐Xue
Publicado 2023