Synthesis and bioactivity of readily hydrolysable novel cationic lipids for potential lung delivery application of mRNAs

por Pei, Yihua, Bao, Yanjie, Sacchetti, Cristiano, Brady, Juthamart, Gillard, Kyra, Yu, Hailong, Roberts, Scott, Rajappan, Kumar, Tanis, Steven P., Perez-Garcia, Carlos G., Chivukula, Padmanabh, Karmali, Priya P.
Publicado 2022

Development of an mRNA replacement therapy for phenylketonuria

por Perez-Garcia, Carlos G., Diaz-Trelles, Ramon, Vega, Jerel Boyd, Bao, Yanjie, Sablad, Marciano, Limphong, Patty, Chikamatsu, Simon, Yu, Hailong, Taylor, Wendy, Karmali, Priya P., Tachikawa, Kiyoshi, Chivukula, Padmanabh
Publicado 2022

A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice

por de Alwis, Ruklanthi, Gan, Esther S., Chen, Shiwei, Leong, Yan Shan, Tan, Hwee Cheng, Zhang, Summer L., Yau, Clement, Low, Jenny G.H., Kalimuddin, Shirin, Matsuda, Daiki, Allen, Elizabeth C., Hartman, Paula, Park, Kyoung-Joo Jenny, Alayyoubi, Maher, Bhaskaran, Hari, Dukanovic, Adrian, Bao, Yanjie, Clemente, Brenda, Vega, Jerel, Roberts, Scott, Gonzalez, Jose A., Sablad, Marciano, Yelin, Rodrigo, Taylor, Wendy, Tachikawa, Kiyoshi, Parker, Suezanne, Karmali, Priya, Davis, Jared, Sullivan, Brian M., Sullivan, Sean M., Hughes, Steve G., Chivukula, Pad, Ooi, Eng Eong
Publicado 2021