Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7

por Switonski, Pawel M., Delaney, Joe R., Bartelt, Luke C., Niu, Chenchen, Ramos-Zapatero, Maria, Spann, Nathanael J., Alaghatta, Akshay, Chen, Toby, Griffin, Emily N., Bapat, Jaidev, Sopher, Bryce L., La Spada, Albert R.
Publicado 2021

Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors

por Delaney, Joe R., Patel, Chandni B., Bapat, Jaidev, Jones, Christian M., Ramos-Zapatero, Maria, Ortell, Katherine K., Tanios, Ralph, Haghighiabyaneh, Mina, Axelrod, Joshua, DeStefano, John W., Tancioni, Isabelle, Schlaepfer, David D., Harismendy, Olivier, La Spada, Albert R., Stupack, Dwayne G.
Publicado 2020

Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer

por Delaney, Joe Ryan, Patel, Chandni B., Willis, Katelyn McCabe, Haghighiabyaneh, Mina, Axelrod, Joshua, Tancioni, Isabelle, Lu, Dan, Bapat, Jaidev, Young, Shanique, Cadassou, Octavia, Bartakova, Alena, Sheth, Parthiv, Haft, Carley, Hui, Sandra, Saenz, Cheryl, Schlaepfer, David D., Harismendy, Olivier, Stupack, Dwayne G.
Publicado 2017

Neuronal Ndst1 depletion accelerates prion protein clearance and slows neurodegeneration in prion infection

por Aguilar-Calvo, Patricia, Malik, Adela, Sandoval, Daniel R., Barback, Christopher, Orrù, Christina D., Standke, Heidi G., Thomas, Olivia R., Dwyer, Chrissa A., Pizzo, Donald P., Bapat, Jaidev, Soldau, Katrin, Ogawa, Ryotaro, Riley, Mckenzie B., Nilsson, K. Peter R., Kraus, Allison, Caughey, Byron, Iliff, Jeffrey J., Vera, David R., Esko, Jeffrey D., Sigurdson, Christina J.
Publicado 2023