Editorial: Metabolism of anti-cancer drugs: Interplay involving pharmacology and pharmacokinetics

por Bapiro, Tashinga E., Hayeshi, Rose, Dandara, Collet
Publicado 2022

Understanding the Complexity of Porous Graphitic Carbon (PGC) Chromatography: Modulation of Mobile-Stationary Phase Interactions Overcomes Loss of Retention and Reduces Variability

por Bapiro, Tashinga E., Richards, Frances M., Jodrell, Duncan I.
Publicado 2016

Paclitaxel and CYC3, an aurora kinase A inhibitor, synergise in pancreatic cancer cells but not bone marrow precursor cells

por Lin, Y, Richards, F M, Krippendorff, B-F, Bramhall, J L, Harrington, J A, Bapiro, T E, Robertson, A, Zheleva, D, Jodrell, D I
Publicado 2012

Anti-Tumour Efficacy of Capecitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer

por Courtin, Aurélie, Richards, Frances M., Bapiro, Tashinga E., Bramhall, Jo L., Neesse, Albrecht, Cook, Natalie, Krippendorff, Ben-Fillippo, Tuveson, David A., Jodrell, Duncan I.
Publicado 2013

SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice

por Neesse, Albrecht, Frese, Kristopher K, Chan, Derek S, Bapiro, Tashinga E, Howat, William J, Richards, Frances M, Ellenrieder, Volker, Jodrell, Duncan I, Tuveson, David A
Publicado 2014

Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo

por Bapiro, T E, Frese, K K, Courtin, A, Bramhall, J L, Madhu, B, Cook, N, Neesse, A, Griffiths, J R, Tuveson, D A, Jodrell, D I, Richards, F M
Publicado 2014

Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma

por Cook, Natalie, Frese, Kristopher K., Bapiro, Tashinga E., Jacobetz, Michael A., Gopinathan, Aarthi, Miller, Jodi L., Rao, Sudhir S., Demuth, Tim, Howat, William J., Jodrell, Duncan I., Tuveson, David A.
Publicado 2012

Anti‐stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma

por Carapuça, Elisabete F, Gemenetzidis, Emilios, Feig, Christine, Bapiro, Tashinga E, Williams, Michael D, Wilson, Abigail S, Delvecchio, Francesca R, Arumugam, Prabhu, Grose, Richard P, Lemoine, Nicholas R, Richards, Frances M, Kocher, Hemant M
Publicado 2016

A novel method for quantification of gemcitabine and its metabolites 2′,2′-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC–MS/MS: comparison with (19)F NMR...

por Bapiro, Tashinga E., Richards, Frances M., Goldgraben, Mae A., Olive, Kenneth P., Madhu, Basetti, Frese, Kristopher K., Cook, Natalie, Jacobetz, Michael A., Smith, Donna-Michelle, Tuveson, David A., Griffiths, John R., Jodrell, Duncan I.
Publicado 2011

Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer

por Hessmann, E, Patzak, M S, Klein, L, Chen, N, Kari, V, Ramu, I, Bapiro, T E, Frese, K K, Gopinathan, A, Richards, F M, Jodrell, D I, Verbeke, C, Li, X, Heuchel, R, Löhr, J M, Johnsen, S A, Gress, T M, Ellenrieder, V, Neesse, A
Publicado 2018

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer

por Jacobetz, Michael A, Chan, Derek S, Neesse, Albrecht, Bapiro, Tashinga E, Cook, Natalie, Frese, Kristopher K, Feig, Christine, Nakagawa, Tomoaki, Caldwell, Meredith E, Zecchini, Heather I, Lolkema, Martijn P, Jiang, Ping, Kultti, Anne, Thompson, Curtis B, Maneval, Daniel C, Jodrell, Duncan I, Frost, Gregory I, Shepard, H M, Skepper, Jeremy N, Tuveson, David A
Publicado 2013

T Cell–Mediated Antitumor Immunity Cooperatively Induced By TGFβR1 Antagonism and Gemcitabine Counteracts Reformation of the Stromal Barrier in Pancreatic Cancer

por Li, Dandan, Schaub, Nicholas, Guerin, Theresa M., Bapiro, Tashinga E., Richards, Frances M., Chen, Vicky, Talsania, Keyur, Kumar, Parimal, Gilbert, Debra J., Schlomer, Jerome J., Kim, Seong-Jin, Sorber, Rebecca, Teper, Yaroslav, Bautista, Wendy, Palena, Claudia, Ock, Chan-Young, Jodrell, Duncan I., Pate, Nathan, Mehta, Monika, Zhao, Yongmei, Kozlov, Serguei, Rudloff, Udo
Publicado 2021