Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

por Mandell, Jeffrey G., Barbas, Carlos F.
Publicado 2006

Synthetic Zinc Finger Proteins: The Advent of Targeted Gene Regulation and Genome Modification Technologies

por Gersbach, Charles A., Gaj, Thomas, Barbas, Carlos F.
Publicado 2014

Redesigning Recombinase Specificity for Safe Harbor Sites in the Human Genome

por Wallen, Mark C., Gaj, Thomas, Barbas, Carlos F.
Publicado 2015

Directed evolution of the TALE N-terminal domain for recognition of all 5′ bases

por Lamb, Brian M., Mercer, Andrew C., Barbas, Carlos F.
Publicado 2013

Improved Cell-Penetrating Zinc-Finger Nuclease Proteins for Precision Genome Engineering

por Liu, Jia, Gaj, Thomas, Wallen, Mark C, Barbas, Carlos F
Publicado 2015

Directed evolution of recombinase specificity by split gene reassembly

por Gersbach, Charles A., Gaj, Thomas, Gordley, Russell M., Barbas, Carlos F.
Publicado 2010

Chimeric TALE recombinases with programmable DNA sequence specificity

por Mercer, Andrew C., Gaj, Thomas, Fuller, Roberta P., Barbas, Carlos F.
Publicado 2012

Improving the Serum Stability of Site-Specific Antibody Conjugates with Sulfone Linkers

por Patterson, James T., Asano, Shigehiro, Li, Xiuling, Rader, Christoph, Barbas, Carlos F.
Publicado 2014

Positive selection of DNA-protein interactions in mammalian cells through phenotypic coupling with retrovirus production

por Tschulena, Ulrich, Peterson, Kenneth R., Gonzalez, Beatriz, Fedosyuk, Halyna, Barbas, Carlos F.
Publicado 2009

Targeted gene knockout by direct delivery of ZFN proteins

por Gaj, Thomas, Guo, Jing, Kato, Yoshio, Sirk, Shannon J., Barbas, Carlos F.
Publicado 2012

Reactivation of Latent HIV-1 Expression by Engineered TALE Transcription Factors

por Perdigão, Pedro, Gaj, Thomas, Santa-Marta, Mariana, Barbas, Carlos F., Goncalves, Joao
Publicado 2016

Expanding the zinc-finger recombinase repertoire: directed evolution and mutational analysis of serine recombinase specificity determinants

por Sirk, Shannon J., Gaj, Thomas, Jonsson, Andreas, Mercer, Andrew C., Barbas, Carlos F.
Publicado 2014

Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase

por Gersbach, Charles A., Gaj, Thomas, Gordley, Russell M., Mercer, Andrew C., Barbas, Carlos F.
Publicado 2011

A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells

por Gaj, Thomas, Mercer, Andrew C., Sirk, Shannon J., Smith, Heather L., Barbas, Carlos F.
Publicado 2013

Regulation of Endogenous Human Gene Expression by Ligand-Inducible TALE Transcription Factors

por Mercer, Andrew C., Gaj, Thomas, Sirk, Shannon J., Lamb, Brian M., Barbas, Carlos F.
Publicado 2013

Protein Delivery of Cell-Penetrating Zinc-Finger Activators Stimulates Latent HIV-1-Infected Cells

por Perdigão, Pedro R.L., Cunha-Santos, Catarina, Barbas, Carlos F., Santa-Marta, Mariana, Goncalves, Joao
Publicado 2020

Episomal vectors based on S/MAR and the β-globin Replicator, encoding a synthetic transcriptional activator, mediate efficient γ-globin activation in haematopoietic cells

por Stavrou, Eleana F., Simantirakis, Emannuouil, Verras, Meletios, Barbas, Carlos, Vassilopoulos, George, Peterson, Kenneth R., Athanassiadou, Aglaia
Publicado 2019

Enhancing the Specificity of Recombinase-Mediated Genome Engineering through Dimer Interface Redesign

por Gaj, Thomas, Sirk, Shannon J., Tingle, Ryan D., Mercer, Andrew C., Wallen, Mark C., Barbas, Carlos F.
Publicado 2014

Induction of Fetal Hemoglobin In Vivo Mediated by a Synthetic γ-Globin Zinc Finger Activator

por Costa, Flávia C., Fedosyuk, Halyna, Neades, Renee, de Los Rios, Johana Bravo, Barbas, Carlos F., Peterson, Kenneth R.
Publicado 2012

Highly Specific Blood-Brain Barrier Transmigrating Single-Domain Antibodies Selected by an In Vivo Phage Display Screening

por Aguiar, Sandra Isabel, Dias, Joana N. R., André, Ana Santos, Silva, Marta Lisete, Martins, Diana, Carrapiço, Belmira, Castanho, Miguel, Carriço, João, Cavaco, Marco, Gaspar, Maria Manuela, Nobre, Rui Jorge, Pereira de Almeida, Luís, Oliveira, Soraia, Gano, Lurdes, Correia, João D. G., Barbas, Carlos, Gonçalves, João, Neves, Vera, Aires-da-Silva, Frederico
Publicado 2021