SCF Fbx4/alphaB-crystallin cyclin D1 ubiquitin ligase: a license to destroy

por Barbash, Olena, Lin, Douglas I, Diehl, J Alan
Publicado 2007

Phosphorylation-dependent regulation of SCF(Fbx4) dimerization and activity involves a novel component, 14-3-3ε

por Barbash, Olena, Lee, Eric K., Diehl, J Alan
Publicado 2011

A Chemical Acetylation-Based Mass Spectrometry Platform for Histone Methylation Profiling

por Zappacosta, Francesca, Wagner, Craig D., Della Pietra, Anthony, Gerhart, Sarah V., Keenan, Kathryn, Korenchuck, Susan, Quinn, Chad J., Barbash, Olena, McCabe, Michael T., Annan, Roland S.
Publicado 2021

Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer

por Wyce, Anastasia, Degenhardt, Yan, Bai, Yuchen, Le, BaoChau, Korenchuk, Susan, Crouthamel, Ming-Chih, McHugh, Charles F., Vessella, Robert, Creasy, Caretha L., Tummino, Peter J., Barbash, Olena
Publicado 2013

Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation

por Van Aller, Glenn S., Reynoird, Nicolas, Barbash, Olena, Huddleston, Michael, Liu, Shichong, Zmoos, Anne-Flore, McDevitt, Patrick, Sinnamon, Robert, Le, BaoChau, Mas, Gloria, Annan, Roland, Sage, Julien, Garcia, Benjamin A., Tummino, Peter J., Gozani, Or, Kruger, Ryan G.
Publicado 2012

PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression

por Chiang, Kelly, Zielinska, Agnieszka E., Shaaban, Abeer M., Sanchez-Bailon, Maria Pilar, Jarrold, James, Clarke, Thomas L., Zhang, Jingxian, Francis, Adele, Jones, Louise J., Smith, Sally, Barbash, Olena, Guccione, Ernesto, Farnie, Gillian, Smalley, Matthew J., Davies, Clare C.
Publicado 2017

SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

por Mazur, Pawel K., Reynoird, Nicolas, Khatri, Purvesh, Jansen, Pascal W.T.C., Wilkinson, Alex, Liu, Shichong, Barbash, Olena, Van Aller, Glenn S., Huddleston, Michael, Dhanak, Dashyant, Tummino, Peter J., Kruger, Ryan G., Garcia, Benjamin, Butte, Atul J., Vermeulen, Michiel, Sage, Julien, Gozani, Or
Publicado 2014

Activation of the p53-MDM4 regulatory axis defines the anti-tumour response to PRMT5 inhibition through its role in regulating cellular splicing

por Gerhart, Sarah V., Kellner, Wendy A., Thompson, Christine, Pappalardi, Melissa B., Zhang, Xi-Ping, Montes de Oca, Rocio, Penebre, Elayne, Duncan, Kenneth, Boriack-Sjodin, Ann, Le, BaoChau, Majer, Christina, McCabe, Michael T., Carpenter, Chris, Johnson, Neil, Kruger, Ryan G., Barbash, Olena
Publicado 2018

MEK inhibitors overcome resistance to BET inhibition across a number of solid and hematologic cancers

por Wyce, Anastasia, Matteo, Jeanne J., Foley, Shawn W., Felitsky, Daniel J., Rajapurkar, Satyajit R., Zhang, Xi-Ping, Musso, Melissa C., Korenchuk, Susan, Karpinich, Natalie O., Keenan, Kathryn M., Stern, Melissa, Mathew, Lijoy K., McHugh, Charles F., McCabe, Michael T., Tummino, Peter J., Kruger, Ryan G., Carpenter, Christopher, Barbash, Olena
Publicado 2018

BET Inhibition Silences Expression of MYCN and BCL2 and Induces Cytotoxicity in Neuroblastoma Tumor Models

por Wyce, Anastasia, Ganji, Gopinath, Smitheman, Kimberly N., Chung, Chun-wa, Korenchuk, Susan, Bai, Yuchen, Barbash, Olena, Le, BaoChau, Craggs, Peter D., McCabe, Michael T., Kennedy-Wilson, Karen M., Sanchez, Lydia V., Gosmini, Romain L., Parr, Nigel, McHugh, Charles F., Dhanak, Dashyant, Prinjha, Rab K., Auger, Kurt R., Tummino, Peter J.
Publicado 2013

Homologous Recombination Deficiency: Concepts, Definitions, and Assays

por Stewart, Mark D, Merino Vega, Diana, Arend, Rebecca C, Baden, Jonathan F, Barbash, Olena, Beaubier, Nike, Collins, Grace, French, Tim, Ghahramani, Negar, Hinson, Patsy, Jelinic, Petar, Marton, Matthew J, McGregor, Kimberly, Parsons, Jerod, Ramamurthy, Lakshman, Sausen, Mark, Sokol, Ethan S, Stenzinger, Albrecht, Stires, Hillary, Timms, Kirsten M, Turco, Diana, Wang, Iris, Williams, J Andrew, Wong-Ho, Elaine, Allen, Jeff
Publicado 2022

TP53 mutations and RNA-binding protein MUSASHI-2 drive resistance to PRMT5-targeted therapy in B-cell lymphoma

por Erazo, Tatiana, Evans, Chiara M., Zakheim, Daniel, Chu, Karen L., Refermat, Alice Yunsi, Asgari, Zahra, Yang, Xuejing, Da Silva Ferreira, Mariana, Mehta, Sanjoy, Russo, Marco Vincenzo, Knezevic, Andrea, Zhang, Xi-Ping, Chen, Zhengming, Fennell, Myles, Garippa, Ralph, Seshan, Venkatraman, de Stanchina, Elisa, Barbash, Olena, Batlevi, Connie Lee, Leslie, Christina S., Melnick, Ari M., Younes, Anas, Kharas, Michael G.
Publicado 2022

Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors

por Piha-Paul, Sarina A, Hann, Christine L, French, Christopher A, Cousin, Sophie, Braña, Irene, Cassier, Phillippe A, Moreno, Victor, de Bono, Johann S, Harward, Sara Duckworth, Ferron-Brady, Geraldine, Barbash, Olena, Wyce, Anastasia, Wu, Yuehui, Horner, Thierry, Annan, Meg, Parr, Nigel J, Prinjha, Rabinder K, Carpenter, Christopher L, Hilton, John, Hong, David S, Haas, Naomi B, Markowski, Mark C, Dhar, Arindam, O’Dwyer, Peter J, Shapiro, Geoffrey I
Publicado 2019

A Phase I/II Open-Label Study of Molibresib for the Treatment of Relapsed/Refractory Hematologic Malignancies

por Dawson, Mark A., Borthakur, Gautam, Huntly, Brian J.P., Karadimitris, Anastasios, Alegre, Adrian, Chaidos, Aristeidis, Vogl, Dan T., Pollyea, Daniel A., Davies, Faith E., Morgan, Gareth J., Glass, Jacob L., Kamdar, Manali, Mateos, Maria-Victoria, Tovar, Natalia, Yeh, Paul, Delgado, Regina García, Basheer, Faisal, Marando, Ludovica, Gallipoli, Paolo, Wyce, Anastasia, Krishnatry, Anu Shilpa, Barbash, Olena, Bakirtzi, Evi, Ferron-Brady, Geraldine, Karpinich, Natalie O., McCabe, Michael T., Foley, Shawn W., Horner, Thierry, Dhar, Arindam, Kremer, Brandon E., Dickinson, Michael
Publicado 2023

Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia

por Bell, Charles C., Fennell, Katie A., Chan, Yih-Chih, Rambow, Florian, Yeung, Miriam M., Vassiliadis, Dane, Lara, Luis, Yeh, Paul, Martelotto, Luciano G., Rogiers, Aljosja, Kremer, Brandon E., Barbash, Olena, Mohammad, Helai P., Johanson, Timothy M., Burr, Marian L., Dhar, Arindam, Karpinich, Natalie, Tian, Luyi, Tyler, Dean S., MacPherson, Laura, Shi, Junwei, Pinnawala, Nathan, Yew Fong, Chun, Papenfuss, Anthony T., Grimmond, Sean M., Dawson, Sarah-Jane, Allan, Rhys S., Kruger, Ryan G., Vakoc, Christopher R., Goode, David L., Naik, Shalin H., Gilan, Omer, Lam, Enid Y. N., Marine, Jean-Christophe, Prinjha, Rab K., Dawson, Mark A.
Publicado 2019