Astrocyte-based cell therapy: new hope for amyotrophic lateral sclerosis patients?

por Barbeito, Luis
Publicado 2018

Phenotypic heterogeneity of astrocytes in motor neuron disease

por Trias, Emiliano, Barbeito, Luis, Yamanaka, Koji
Publicado 2018

Increased blood–brain barrier permeability and alterations in perivascular astrocytes and pericytes induced by intracisternal glutaric acid

por Isasi, Eugenia, Barbeito, Luis, Olivera-Bravo, Silvia
Publicado 2014

Extracellular ATP and the P2X(7 )receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis

por Gandelman, Mandi, Peluffo, Hugo, Beckman, Joseph S, Cassina, Patricia, Barbeito, Luis
Publicado 2010

Neonatal Astrocyte Damage Is Sufficient to Trigger Progressive Striatal Degeneration in a Rat Model of Glutaric Acidemia-I

por Olivera-Bravo, Silvia, Fernández, Anabel, Sarlabós, María Noel, Rosillo, Juan Carlos, Casanova, Gabriela, Jiménez, Marcie, Barbeito, Luis
Publicado 2011

Modulation of Astrocytic Mitochondrial Function by Dichloroacetate Improves Survival and Motor Performance in Inherited Amyotrophic Lateral Sclerosis

por Miquel, Ernesto, Cassina, Adriana, Martínez-Palma, Laura, Bolatto, Carmen, Trías, Emiliano, Gandelman, Mandi, Radi, Rafael, Barbeito, Luis, Cassina, Patricia
Publicado 2012

Emergence of Microglia Bearing Senescence Markers During Paralysis Progression in a Rat Model of Inherited ALS

por Trias, Emiliano, Beilby, Pamela R., Kovacs, Mariángeles, Ibarburu, Sofía, Varela, Valentina, Barreto-Núñez, Romina, Bradford, Samuel C., Beckman, Joseph S., Barbeito, Luis
Publicado 2019

Isolation and Characterization of Ischemia-Derived Astrocytes (IDAs) with Ability to Transactivate Quiescent Astrocytes

por Villarreal, Alejandro, Rosciszewski, Gerardo, Murta, Veronica, Cadena, Vanesa, Usach, Vanina, Dodes-Traian, Martin M., Setton-Avruj, Patricia, Barbeito, Luis H., Ramos, Alberto J.
Publicado 2016

CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS

por Kovacs, Mariángeles, Trias, Emiliano, Varela, Valentina, Ibarburu, Sofia, Beckman, Joseph S., Moura, Ivan C., Hermine, Olivier, King, Peter H., Si, Ying, Kwon, Yuri, Barbeito, Luis
Publicado 2019

Phenotypic transition of microglia into astrocyte-like cells associated with disease onset in a model of inherited ALS

por Trias, Emiliano, Díaz-Amarilla, Pablo, Olivera-Bravo, Silvia, Isasi, Eugenia, Drechsel, Derek A., Lopez, Nathan, Bradford, C. Samuel, Ireton, Kyle E., Beckman, Joseph S., Barbeito, Luis
Publicado 2013

The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS

por Kovacs, Mariángeles, Alamón, Catalina, Maciel, Cecilia, Varela, Valentina, Ibarburu, Sofía, Tarragó, Lucas, King, Peter H., Si, Ying, Kwon, Yuri, Hermine, Olivier, Barbeito, Luis, Trias, Emiliano
Publicado 2021

Sunitinib-Containing Carborane Pharmacophore with the Ability to Inhibit Tyrosine Kinases Receptors FLT3, KIT and PDGFR-β, Exhibits Powerful In Vivo Anti-Glioblastoma Activity

por Alamón, Catalina, Dávila, Belén, García, María Fernanda, Sánchez, Carina, Kovacs, Mariángeles, Trias, Emiliano, Barbeito, Luis, Gabay, Martín, Zeineh, Nidal, Gavish, Moshe, Teixidor, Francesc, Viñas, Clara, Couto, Marcos, Cerecetto, Hugo
Publicado 2020

Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis

por Trias, Emiliano, Ibarburu, Sofía, Barreto-Núñez, Romina, Babdor, Joël, Maciel, Thiago T., Guillo, Matthias, Gros, Laurent, Dubreuil, Patrice, Díaz-Amarilla, Pablo, Cassina, Patricia, Martínez-Palma, Laura, Moura, Ivan C., Beckman, Joseph S., Hermine, Olivier, Barbeito, Luis
Publicado 2016

PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease

por Duhalde Vega, Maite, Olivera, Daniela, Gastão Davanzo, Gustavo, Bertullo, Mauricio, Noya, Verónica, Fabiano de Souza, Gabriela, Primon Muraro, Stéfanie, Castro, Icaro, Arévalo, Ana Paula, Crispo, Martina, Galliussi, Germán, Russo, Sofía, Charbonnier, David, Rammauro, Florencia, Jeldres, Mathías, Alamón, Catalina, Varela, Valentina, Batthyany, Carlos, Bollati-Fogolín, Mariela, Oppezzo, Pablo, Pritsch, Otto, Proença-Módena, José Luiz, Nakaya, Helder I., Trias, Emiliano, Barbeito, Luis, Anegon, Ignacio, Cuturi, María Cristina, Moraes-Vieira, Pedro, Segovia, Mercedes, Hill, Marcelo
Publicado 2022