C. elegans dkf-1 (Protein Kinase D1) mutants have age-dependent defects in locomotion and neuromuscular transmission

por Johnson, James R., Barclay, Jeff W.
Publicado 2023

A Caenorhabditis elegans model of autosomal dominant adult-onset neuronal ceroid lipofuscinosis identifies ethosuximide as a potential therapeutic

por Barker, Eleanor, Morgan, Alan, Barclay, Jeff W
Publicado 2022

Rab-3 and unc-18 Interactions in Alcohol Sensitivity Are Distinct from Synaptic Transmission

por Johnson, James R., Kashyap, Sudhanva, Rankin, Kim, Barclay, Jeff W.
Publicado 2013

Using C. elegans to discover therapeutic compounds for ageing-associated neurodegenerative diseases

por Chen, Xi, Barclay, Jeff W., Burgoyne, Robert D., Morgan, Alan
Publicado 2015

Expression profile of a Caenorhabditis elegans model of adult neuronal ceroid lipofuscinosis reveals down regulation of ubiquitin E3 ligase components

por McCue, Hannah V., Chen, Xi, Barclay, Jeff W., Morgan, Alan, Burgoyne, Robert D.
Publicado 2015

Small Heat Shock Proteins Are Novel Common Determinants of Alcohol and Nicotine Sensitivity in Caenorhabditis elegans

por Johnson, James R., Rajamanoharan, Dayani, McCue, Hannah V., Rankin, Kim, Barclay, Jeff W.
Publicado 2016

Identification of key structural elements for neuronal calcium sensor-1 function in the regulation of the temperature-dependency of locomotion in C. elegans

por Martin, Victoria M, Johnson, James R, Haynes, Lee P, Barclay, Jeff W, Burgoyne, Robert D
Publicado 2013

Interaction of ARF-1.1 and neuronal calcium sensor-1 in the control of the temperature-dependency of locomotion in Caenorhabditis elegans

por Todd, Paul A. C., McCue, Hannah V., Haynes, Lee P., Barclay, Jeff W., Burgoyne, Robert D.
Publicado 2016

Functional analysis of epilepsy‐associated variants in STXBP1/Munc18‐1 using humanized Caenorhabditis elegans

por Zhu, Bangfu, Mak, Jennifer C. H., Morris, Andrew P., Marson, Anthony G., Barclay, Jeff W., Sills, Graeme J., Morgan, Alan
Publicado 2020

Erratum to: Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression

por Chen, Xi, McCue, Hannah V., Wong, Shi Quan, Kashyap, Sudhanva S., Kraemer, Brian C., Barclay, Jeff W., Burgoyne, Robert D., Morgan, Alan
Publicado 2015

Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression

por Chen, Xi, McCueF, Hannah V., Wong, Shi Quan, Kashyap, Sudhanva S., Kraemer, Brian C., Barclay, Jeff W., Burgoyne, Robert D., Morgan, Alan
Publicado 2015

Structure-Function Study of Mammalian Munc18-1 and C. elegans UNC-18 Implicates Domain 3b in the Regulation of Exocytosis

por Graham, Margaret E., Prescott, Gerald R., Johnson, James R., Jones, Mathew, Walmesley, Alice, Haynes, Lee P., Morgan, Alan, Burgoyne, Robert D., Barclay, Jeff W.
Publicado 2011

Ethanol Stimulates Locomotion via a G(αs)-Signaling Pathway in IL2 Neurons in Caenorhabditis elegans

por Johnson, James R., Edwards, Mark R., Davies, Huw, Newman, Daniel, Holden, Whitney, Jenkins, Rosalind E., Burgoyne, Robert D., Lucas, Robert J., Barclay, Jeff W.
Publicado 2017

A Caenorhabditis elegans assay of seizure-like activity optimised for identifying antiepileptic drugs and their mechanisms of action

por Wong, Shi Quan, Jones, Alistair, Dodd, Steven, Grimes, Douglas, Barclay, Jeff W., Marson, Anthony G., Cunliffe, Vincent T., Burgoyne, Robert D., Sills, Graeme J., Morgan, Alan
Publicado 2018

Proteomic analysis of dietary restriction in yeast reveals a role for Hsp26 in replicative lifespan extension

por Campion, Richard, Bloxam, Leanne, Burrow, Kimberley, Brownridge, Philip J., Pentland, Daniel R., Thomas, Patricia, Gourlay, Campbell W., Eyers, Claire E., Barclay, Jeff W., Morgan, Alan
Publicado 2021

α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy

por Wong, Shi Quan, Pontifex, Matthew G., Phelan, Marie M., Pidathala, Chandra, Kraemer, Brian C., Barclay, Jeff W., Berry, Neil G., O'Neill, Paul M., Burgoyne, Robert D., Morgan, Alan
Publicado 2018

Evidence for involvement of the alcohol consumption WDPCP gene in lipid metabolism, and liver cirrhosis

por O’Farrell, Felix, Aleyakpo, Benjamin, Mustafa, Rima, Jiang, Xiyun, Pinto, Rui Climaco, Elliott, Paul, Tzoulaki, Ioanna, Dehghan, Abbas, Loh, Samantha H. Y., Barclay, Jeff W., Martins, L. Miguel, Pazoki, Raha
Publicado 2023

Caenorhabditis elegans dnj-14, the orthologue of the DNAJC5 gene mutated in adult onset neuronal ceroid lipofuscinosis, provides a new platform for neuroprotective drug screening a...

por Kashyap, Sudhanva S., Johnson, James R., McCue, Hannah V., Chen, Xi, Edmonds, Matthew J., Ayala, Mimieveshiofuo, Graham, Margaret E., Jenn, Robert C., Barclay, Jeff W., Burgoyne, Robert D., Morgan, Alan
Publicado 2014