Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery

por Zhan, Yanai, Kost-Alimova, Maria, Shi, Xi, Leo, Elisabetta, Bardenhagen, Jennifer P., Shepard, Hannah E., Appikonda, Srikanth, Vangamudi, Bhavatarini, Zhao, Shuping, Tieu, Trang N., Jiang, Shiming, Heffernan, Timothy P., Marszalek, Joseph R., Toniatti, Carlo, Draetta, Giulio, Tyler, Jessica, Barton, Michelle, Jones, Philip, Palmer, Wylie S., Geck Do, Mary K., Andersen, Jannik N.
Publicado 2015

NOTUM inhibition increases endocortical bone formation and bone strength

por Brommage, Robert, Liu, Jeff, Vogel, Peter, Mseeh, Faika, Thompson, Andrea Y., Potter, David G., Shadoan, Melanie K., Hansen, Gwenn M., Jeter-Jones, Sabrina, Cui, Jie, Bright, Dawn, Bardenhagen, Jennifer P., Doree, Deon D., Movérare-Skrtic, Sofia, Nilsson, Karin H., Henning, Petra, Lerner, Ulf H., Ohlsson, Claes, Sands, Arthur T., Tarver, James E., Powell, David R., Zambrowicz, Brian, Liu, Qingyun
Publicado 2019

PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma

por Giuliani, Virginia, Miller, Meredith A., Liu, Chiu-Yi, Hartono, Stella R., Class, Caleb A., Bristow, Christopher A., Suzuki, Erika, Sanz, Lionel A., Gao, Guang, Gay, Jason P., Feng, Ningping, Rose, Johnathon L., Tomihara, Hideo, Daniele, Joseph R., Peoples, Michael D., Bardenhagen, Jennifer P., Geck Do, Mary K., Chang, Qing E., Vangamudi, Bhavatarini, Vellano, Christopher, Ying, Haoqiang, Deem, Angela K., Do, Kim-Anh, Genovese, Giannicola, Marszalek, Joseph R., Kovacs, Jeffrey J., Kim, Michael, Fleming, Jason B., Guccione, Ernesto, Viale, Andrea, Maitra, Anirban, Emilia Di Francesco, M., Yap, Timothy A., Jones, Philip, Draetta, Giulio, Carugo, Alessandro, Chedin, Frederic, Heffernan, Timothy P.
Publicado 2021